Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long-term iodine prophylaxis and abundant iodine intake

Clinical Endocrinology

Volumn 47, Issue 1, 1997, Pages 87-92

  Szabolcs, István ^a   Podoba, Jan ^b   Feldkamp, Joachim ^c   Dohán, Orsolya ^a   Farkas, Ildikó ^d   Sajgó, Mihályné ^d   Takáts, Krisztina I ^a   Góth, Miklós ^a   Kovács, László ^a   Kressinszky, Katalin ^a   Hnilica, Peter ^b   Szilágyi, Géza ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d Dept of Human Genet/Teratology   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HYPOTHYROIDISM; IODINE DEFICIENCY; MAJOR CLINICAL STUDY; MALE; NURSING HOME; PREVALENCE; PRIORITY JOURNAL; PROPHYLAXIS; THYROID DISEASE;

EID: 8544249896     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1997.2271040.x     Document Type: Article

References (34)

1. Berghout, A., Wiersinga, W.M., Smits, N.J. & Touber, J.L. (1990) Interrelationships between age, thyroid volume, thyroid nodularity, and thyroid function in patients with sporadic nontoxic goitre. American Journal of Medicine, 89, 602-608.
2. Bornet, H., Madec, A.M. & Rodien, P. (1990) Evaluation of anti-TPO antibody determination in various clinical situations. In Thyroperoxidase and Thyroid Autoimmunity (ed. P. Carayon & J. Ruf), pp. 315-320. INSERM/John Libbey Eurotext Ltd.
3. Braverman, L.E., Ingbar, S.H., Vagenakis, A.G., Adams, L. & Maloof, F. (1971) Enhanced susceptibility to iodide myxedema in patients with Hashimoto's disease. The Journal of Clinical Endocrinology & Metabolism, 32, 51-55.
4. Brochmann, H., Bjoro, T., Gaarder, P.I., Hanson, F. & Frey, H.M. (1988) Prevalence of thyroid dysfunction in elderly subjects. A randomized study in a Norwegian rural community (Naeroy). Acta Endocrinologica (Copenhagen), 117, 7-12.
5. Brunn, J., Block, U., Ruf, G., Bos, I., Kunze, W.P. & Scriba, P.C. (1981) Volumetrie der Schilddrüsenlappen mittels Real-time-Sonography. Deutsche Medizinische Wochenschrift, 106, 1338-1340.
6. Drinka, P.J. & Nolten, W.E. (1990) Prevalence of previously undiagnosed hypothyroidism in residents of a midwestern nursing home. Southern Medical Journal, 83, 1259-1261.
7. Gönczi, J., Szabolcs, I., Kovács, Zs., Kakosy, T., Goth, M. & Szilagyi, G. (1994) Ultrasonography of the thyroid gland in hospitalized, chronically ill geriatric patients: thyroid volume, its relationship to age and disease, and the prevalence of diffuse and nodular goitre. Journal of Clinical Ultrasound, 22, 257-261.
8. Gutekunst, R., Smolarek, H., Hasenpusch, H., Stubbe, P., Friedrich, H.J., Wood, W.G. & Scriba, P.C. (1986) Goiter epidemiology: thyroid volume, iodine excretion, thyroglobulin and thyrotropin in Germany and Sweden. Acta Endocrinologica (Copenhagen), 112, 494-501.
9. Hegedus, L., Perrild, H., Poulsen, L.R., Andersen, J.R., Holm, B., Schnohn, P., Jensen, G. & Hansen, J.M. (1983) The determination of thyroid volume by ultrasound and its relationship to body weight, age, and sex in normal subjects. The Journal of Clinical Endocrinology & Metabolism, 56, 260-263.
10. Heikoff, L.E., Luxenberg, J. & Feigenbaum, L.Z. (1984) Low yield of screening for hypothyroidism in healthy elderly. Journal of the American Geriatrics Society, 32, 616-617.
11. Helfand, M. & Crapo, L.M. (1990) Screening for thyroid disease. Annals of Internal Medicine, 112, 840-849.
12. Herrmann, J. (1981) Prevalence of hypothyroidism in the elderly in Germany: a pilot study. Journal of Endocrinological Investigation, 4, 327-330.
13. Hintze, G., Burghardt, U., Baumert, J., Winderler, J. & Köbberling, J. (1991) Prevalence of thyroid dysfunction in elderly subjects from the general population in an iodine deficiency area. Aging, 3, 325-331.
14. Inada, M., Nishikawa, M. & Kawai, I. (1983) Hypothyroidism associated with positive results of the perchlorate discharge test in elderly patients. American Journal of Medicine, 74, 1010-1015.
15. Laurberg, P., Hreidarsson, A.B., Pedersen, K.B., Sigfusson, N. & Iversen, E. (1995) High frequency of goitre and subclinical hyperthyroidism in a low iodine intake area versus high frequency of subclinical hypothyroidism in a high iodine intake area. A comparative epidemiological study in elderly subjects. Thyroid, 5 (Suppl. 1), Abstract 273.
16. Mariotti, S., Sansoni, P., Barbesino, G., Caturegli, P., Monti, D., Cossarizza, A., Giacomelli, T., Passeri, G., Fagiolo, U., Pinchera, A. & Franceschi, C. (1992) Thyroid and other organ-specific autoantibodies in healthy centenarians. Lancet, 339, 1506-1508.
17. Oberhofer, R., Ober, A., Oberkofler, F. & Amor, H. (1989) Schilddrüsenvolumen gesunder Erwachsener in einem Strumaendemiegebiet. Acta Medica Austriaca, 16, 38-41.
18. Okamura, K., Ueda, K., Sone, H., Ikenoue, H., Hasuo, Y., Sato, K., Yoshinari, M. & Fujishima, M. (1989) A sensitive thyroid stimulating hormone assay for screening of thyroid functional disorder in elderly Japanese. Journal of the American Geriatrics Society, 37, 317-322.
19. Olbricht, T., Schmitka, T., Mellinghoff, U., Benker, G. & Reinwein, D. (1983) Sonographische Bestimmung von Schilddrüsenvolumina bei Schilddrüsengesunden. Deutsche Medizinische Wochenschrift, 108, 1355-1358.
20. Parle, J.V., Franklyn, A., Cross, K.W., Jones, S.C. & Sheppard, M.C. (1991) Prevalence and follow-up of abnormal thyrotropin (TSH) concentrations in the elderly in the United Kingdom. Clinical Endocrinology, 34, 77-83.
21. Rae, P., Farrar, J., Beckett, G. & Toft, A. (1993) Assessment of thyroid status in elderly people. British Medical Journal, 307, 177-180.
22. Robuschi, G., Safran, M., Braverman, L.E., Gnudi, A. & Roti, E. (1987) Hypothyroidism in the elderly. Endocrine Reviews, 8, 142-153.
23. Rosenthal, M.J., Hunt, W.C., Garry, P.J. & Goodwin, J.S. (1987) Thyroid failure in the elderly. Microsomal antibodies as discriminant for therapy. JAMA, 258, 209-213.
24. Roti, E., Minella, R., Gardini, E., Bianconi, L. & Braverman, L.E. (1990) Iodine-induced hypothyroidism in euthyroid subjects with a previous episode of subacute thyroiditis. The Journal of Clinical Endocrinology & Metabolism, 70, 1581-1585.
25. Roti, E., Minelli, R., Gardini, E., Bianconi, L., Neri, T., Gavaruzzi, G., Ugolotti, G., Salvo, D. & Braverman, L.E. (1991) Impaired intrathyroidal iodine organification and iodine-induced hypothyroidism in euthyroid women with previous episode of postpartum thyroiditis. The Journal of Clinical Endocrinology & Metabolism, 73, 958-963.
26. Roti, E., Gardini, E., Minella, R., Bianconi, L. & Braverman, L.E. (1992) Prevalence of anti-thyroid peroxidase antibodies in serum in the elderly: Comparison with other tests for anti-thyroid antibodies. Clinical Chemistry, 38, 88-92.
27. Roti, E., Gardini, E., Minelli, R., Bianconi, L., Salvi, M., Gavaruzzi, G. & Braverman, L.E. (1993) Effects of chronic iodine administration on thyroid status in euthyroid subjects previously treated with antithyroid drugs for Graves' hyperthyroidism. The Journal of Clinical Endocrinology & Metabolism, 76, 928-932.
28. Saller, B., Höhrmann, R. & Mann, K. (1991) Heterogeneity of autoantibodies against thyroid peroxidase in autoimmune thyroid disease: evidence against antibodies directly inhibiting peroxidase activity as regulatory factors in thyroid hormone metabolism. The Journal of Clinical Endocrinology & Metabolism, 72, 188-195.
29. Sawin, C.T., Castelli, W.P., Hershman, J.M., McNamara, P. & Bacharach, P. (1985) The aging thyroid. Thyroid deficiency in the Framingham study. Archives of Internal Medicine, 145, 1386-1388.
30. Sundbeck, G., Eden, S., Jagenburg, R. & Lindstedt, G. (1991) Thyroid dysfunction in 85-year-old men and women. Influence of nonthyroidal illness and drug treatment. Acta Endocrinologica (Copenhagen), 125, 475-486.
31. Szabolcs, I., Ploenes, Chr., Bernard, W. & Herrmann, J. (1990) Screening of geriatric patients for thyroid dysfunction with thyrotropin-releasing-hormone test, sensitive thyrotropin and free thyroxine estimation. Hormone and Metabolic Research, 22, 298-302.
32. Szabolcs, I., Bernard, W. & Horster, F.A. (1995a) Thyroid autoantibodies in hospitalized chronic geriatric patients: prevalence, effects of age, nonthyroidal clinical state, and thyroid function. Journal of the American Geriatrics Society, 43, 670-673.
33. Szabolcs, I., Kovács, Zs., Gönczi, J., Kákosy, T., Góth, M., Dohán, O., Kovács, L. & Szilágyi, G. (1995b) Prevalence of thyroid dysfunction in different geriatric subpopulations from a moderately iodine-deficient Hungarian region. Comparative clinical and hormonal screening. European Journal of Endocrinology, 133, 294-299.
34. Wawschinek, O., Eber, O., Petek, W., Wakonig, P. & Gürakar, A. (1985) Bestimmung der Harnjodausscheidung mittels einer modifizierten Cer-Arsenitmethode. Berichte der österreichischen Gesellschaft für Klinische Chemie, 8, 13-15.