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Volumn 57, Issue 10, 2009, Pages 1040-1044
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Improvement of dissolution property of poorly water-soluble drug by supercritical freeze granulation
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Author keywords
Dissolution rate; Micronization; Poorly water soluble drug; Supercritical freeze granulation
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Indexed keywords
CARBON DIOXIDE;
EXCIPIENT;
FLURBIPROFEN;
LACTOSE;
SOLVENT;
WATER;
ARTICLE;
ATMOSPHERIC PRESSURE;
CONTROLLED STUDY;
CRYSTALLIZATION;
DISPERSION;
DRUG DESIGN;
DRUG SOLUBILITY;
FLOW RATE;
NEBULIZATION;
PARTICLE SIZE;
PRESSURE;
RAPID EXPANSION OF SUPERCRITICAL SOLUTION;
SUPERCRITICAL FREEZE GRANULATION;
SURFACE PROPERTY;
TECHNIQUE;
TEMPERATURE;
CARBON DIOXIDE;
FLURBIPROFEN;
FREEZING;
LACTOSE;
PARTICLE SIZE;
SOLUBILITY;
WATER;
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EID: 70349682573
PISSN: 00092363
EISSN: 13475223
Source Type: Journal
DOI: 10.1248/cpb.57.1040 Document Type: Article |
Times cited : (11)
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References (7)
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