Macroprolactinaemia: Prevalence and aetiologies in a large group of hospital workers

Clinical Endocrinology

Volumn 71, Issue 5, 2009, Pages 702-708

  Hattori, Naoki ^a   Ishihara, Takashi ^b   Saiki, Yasuhiko ^b  

^a Ritsumeikan University   (Japan)

^b KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; MACROGOL; PROLACTIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; COVALENT BOND; ENDOCRINE DISEASE; FEMALE; GLYCOSYLATION; HEPATITIS B VIRUS; HUMAN; HYPERPROLACTINEMIA; MACROPROLACTINAEMIA; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROTEIN AGGREGATION; SCREENING TEST;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; FEMALE; HOSPITALS; HUMANS; HYPERPROLACTINEMIA; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PREVALENCE; PROLACTIN; YOUNG ADULT;

EID: 70349678935     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03570.x     Document Type: Article

References (38)

1. Münster, K., Helm, P. Schmidt, L. (1992) Secondary amenorrhoea: prevalence and medical contact - a cross-sectional study from a Danish county. British Journal of Obstetrics and Gynaecology, 99, 430 433.
2. The ESHRE Capri Workshop. European Society for Human Reproduction and Embryology (1996) Infertility revisited: the state of the art today and tomorrow. Human Reproduction, 11, 1779 1807.
3. Freeman, M.E., Kanyicska, B., Lerant, A. et al. (2000) Prolactin: structure, function, and regulation of secretion. Physiological Review, 80, 1523 1631.
4. Cook, C.B., Nippoldt, T.B., Kletter, G.B. et al. (1991) Naloxone increases the frequency of pulsatile lutenizing hormone secretion in women with hyperprolactinemia. The Journal of Clinical Endocrinology and Metabolism, 73, 1099 1105.
5. Molitch, M.E. (1992) Pathologic hyperprolactinemia. Endocrinology and Metabolism Clinics of North America, 21, 877 901.
6. Melmed, S. Kleinberg, D. (2008) Anterior pituitary. In : H.M. Kronenberg, S. Melmed, K.S. Polonsky P.R. Larsen ed. Williams Textbook of Endocrinology (11th Edition). Saunders Elsevier, Philadelphia, pp. 155 261.
7. Hattori, N., Ikekubo, K., Ishihara, T. et al. (1994) Correlation of the antibody titers with serum prolactin levels and their clinical course in patients with anti-prolactin autoantibody. European Journal of Endocrinology, 130, 438 445.
8. Bjøro, T., Mørkrid, L., Wergeland, R. et al. (1995) Frequency of hyperprolactinaemia due to large molecular weight prolactin (150-170 kD PRL). Scandinavian Journal of Clinical and Laboratory Investigation, 55, 139 147.
9. Fahie-Wilson, M.N. Soule, S.G. (1997) Macroprolactinaemia: contribution to hyperprolactinaemia in a district general hospital and evaluation of a screening test based on precipitation with polyethylene glycol. Annals of Clinical Biochemistry, 34, 252 258.
10. Olukoga, A.O. Kane, J.W. (1999) Macroprolactinaemia: validation and application of the polyethylene glycol precipitation test and clinical characterization of the condition. Clinical Endocrinology, 51, 119 126.
11. Leslie, H., Courtney, C.H., Bell, P.M. et al. (2001) Laboratory and clinical experience in 55 patients with macroprolactinemia identified by a simple polyethylene glycol precipitation method. Journal of Clinical Endocrinology and Metababolism, 86, 2743 2746.
12. Vallette-Kasic, S., Morange-Ramos, I., Selim, A. et al. (2002) Macroprolactinemia revisited: a study on 106 patients. The Journal of Clinical Endocrinology and Metabolism, 87, 581 588.
13. Gibney, J., Smith, T.P. McKenna, T.J. (2005) The impact on clinical practice of routine screening for macroprolactin. The Journal of Clinical Endocrinology and Metabolism, 90, 3927 3932. (Pubitemid 41058153)
14. Toldy, E., Löcsei, Z., Szabolcs, I. et al. (2003) Macroprolactinemia: the consequences of a laboratory pitfall. Endocrine, 22, 267 273.
15. Strachan, M.W., Teoh, W.L., Don-Wauchope, A.C. et al. (2003) Clinical and radiological features of patients with macroprolactinaemia. Clinical Endocrinology, 59, 339 346.
16. Ellis, M.J., Livesey, J.H. Soule, S.G. (2006) Macroprolactin, big-prolactin and potential effects on the misdiagnosis of hyperprolactinemia using the Beckman Coulter Access Prolactin assay. Clinical Biochemistry, 39, 1028 1034.
17. Hattori, N., Ishihara, T., Ikekubo, K. et al. (1992) Autoantibody to human prolactin in patients with idiopathic hyperprolactinemia. The Journal of Clinical Endocrinology and Metabolism, 75, 1226 1229.
18. Schiettecatte, J., De Schepper, J., Velkeniers, B. et al. (2001) Rapid detection of macroprolactin in the form of prolactin-immunoglobulin G complexes by immunoprecipitation with anti-human IgG-agarose. Clinical Chemistry and Laboratory Medicine, 39, 1244 1248.
19. Pascoe-Lira, D., Duran-Reyes, G., Contreras-Hernández, I. et al. (2001) Frequency of macroprolactinemia due to autoantibodies against prolactin in pregnant women. The Journal of Clinical Endocrinology and Metabolism, 86, 924 929.
20. Sapin, R. Kertesz, G. (2003) Macroprolactin detection by precipitation with protein A-sepharose: a rapid screening method compared with polyethylene glycol precipitation. Clinical Chemistry, 49, 502 505.
21. De Schepper, J., Schiettecatte, J., Velkeniers, B. et al. (2003) Clinical and biological characterization of macroprolactinemia with and without prolactin-IgG complexes. European Journal of Endocrinology, 149, 201 207.
22. Hattori, N. Inagaki, C. (1997) Anti-prolactin (PRL) autoantibodies cause asymptomatic hyperprolactinemia: bioassay and clearance studies of PRL-immunoglobulin G complex. The Journal of Clinical Endocrinology and Metabolism, 82, 3107 3110.
23. Glezer, A., Soares, C.R., Vieira, J.G. et al. (2006) Human macroprolactin displays low biological activity via its homologous receptor in a new sensitive bioassay. The Journal of Clinical Endocrinology and Metabolism, 91, 1048 1055.
24. Leaños-Miranda, A., Cárdenas-Mondragón, G., Rivera-Leaños, R. et al. (2006) Application of new homologous in vitro bioassays for human lactogens to assess the actual bioactivity of human prolactin isoforms in hyperprolactinaemic patients. Clinical Endocrinology, 65, 146 153.
25. Hattori, N., Nakayama, Y., Kitagawa, K. et al. (2008) Anti-prolactin (PRL) autoantibodies suppress PRL bioactivity in patients with macroprolactinemia. Clinical Endocrinology, 68, 72 76.
26. Kavanagh, L., Smith, T.P. McKenna, T.J. (2007) Bioactivity of macroprolactin in the Nb2 bioassay may be explained by dissociation yielding bioactive monomeric prolactin. Clinical Endocrinology, 67, 954.
27. Sluijmer, A.V. Lappöhn, R.E. (1992) Clinical history and outcome of 59 patients with idiopathic hyperprolactinemia. Fertility and Sterility, 58, 72 77.
28. Cattaneo, F.A. Fahie-Wilson, M.N. (2001) Concomitant occurrence of macroprolactin, exercise-induced amenorrhea, and a pituitary lesion: a diagnostic pitfall. Case report. Journal of Neurosurgery, 95, 334 337.
29. Hattori, N. (1996) The frequency of macroprolactinemia in pregnant women and the heterogeneity of its etiologies. The Journal of Clinical Endocrinology and Metabolism, 81, 586 590.
30. Josimovich, J.B., Lavenhar, M.A., Devanesan, M.M. et al. (1987) Heterogeneous distribution of serum prolactin values in apparently healthy young women, and the effects of oral contraceptive medication. Fertility and Sterility 47, 785 791.
31. Vieira, J.G., Tachibana, T.T., Obara, L.H. et al. (1998) Extensive experience and validation of polyethylene glycol precipitation as a screening method for macroprolactinemia. Clinical Chemistry, 44, 1758 1759.
32. Fahie-Wilson, M.N. (1999) Polyethylene glycol precipitation as a screening method for macroprolactinemia. Clinical Chemistry, 45, 436 437.
33. Beltran, L., Fahie-Wilson, M.N., McKenna, T.J. et al. (2008) Serum total prolactin and monomeric prolactin reference intervals determined by precipitation with polyethylene glycol: evaluation and validation on common immunoassay platforms. Clinical Chemistry, 54, 1673 1681.
34. Fineberg, S.E., Biegel, A.A., Durr, K.L. et al. (1991) Presence of insulin autoantibodies as regular feature of nondiabetic repertoire of immunity. Diabetes, 40, 1187 1193.
35. Benvenga, S., Bartolone, L., Squadrito, S. et al. (1997) Thyroid hormone autoantibodies elicited by diagnostic fine needle biopsy. The Journal of Clinical Endocrinology and Metabolism, 82, 4217 4223.
36. Leon, M.A. (1967) Concanavalin A reaction with human normal immunoglobulin G and myeloma immunoglobulin G. Science, 158, 1325 1326.
37. Bonhoff, A., Vuille, J.C., Gomez, F. et al. (1995) Identification of macroprolactin in a patient with asymptomatic hyperprolactinemia as a stable PRL-IgG complex. Experimental and Clinical Endocrinology and Diabetes, 103, 252 255.
38. Walker, A.M., Montgomery, D.W., Saraiya, S. et al. (1995) Prolactin-immunoglobulin G complexes from human serum act as costimulatory ligands causing proliferation of malignant B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 92, 3278 3282.