Human papillomavirus typing and viral gene expression analysis for the triage of women with abnormal results from papanicolaou test smears to colposcopy

Archives of Pathology and Laboratory Medicine

Volumn 133, Issue 10, 2009, Pages 1577-1586

  Antonishyn, Nick A ^a,b   Horsman, Greg B ^b   Kelln, Rod A ^a   Severini, Alberto ^c  

^a UNIVERSITY OF REGINA   (Canada)

^b Saskatchewan Disease Control Laboratory   (Canada)

^c PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN E6; VIRUS DNA; VIRUS RNA;

ARTICLE; COLPOSCOPY; DIAGNOSTIC TEST; FEMALE; GENE EXPRESSION; GENOTYPE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 31; HUMAN TISSUE; MAJOR CLINICAL STUDY; PAPANICOLAOU TEST; PREVALENCE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; UTERINE CERVIX CARCINOMA IN SITU; VIRUS GENE; VIRUS LOAD; VIRUS TYPING; WART VIRUS;

CERVICAL INTRAEPITHELIAL NEOPLASIA; COLPOSCOPY; DNA, VIRAL; FEMALE; GENE EXPRESSION REGULATION, VIRAL; GENES, VIRAL; HUMAN PAPILLOMAVIRUS 16; HUMANS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS INFECTIONS; PREDICTIVE VALUE OF TESTS; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, VIRAL; TRIAGE; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 70349637954     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Munoz N, Bosch F, De Sanjose S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med. 2003;348(6):518-527. (Pubitemid 36159887)
2. Severson J, Evans TY, Lee P, Chan T, Arany I, Tyring S. Human papillomavirus infections: epidemiology, pathogenesis, and therapy. J Cutan Med Surg. 2001;5(1):43-60. (Pubitemid 32588331)
3. Koutsky L. Epidemiology of genital human papillomavirus infection. Am J Med. 1997;102(5A):3-8. (Pubitemid 127695953)
4. Parkin D, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55(2):74-108.
5. Rydstrom C, Tornberg S. Cervical cancer incidence and mortality in the best and worst of worlds. Scand J Public Health. 2006;34(3):295-303.
6. Sasieni P, Cuzick J, Lynch-Farmery E. Estimating the efficacy of screening by auditing smear histories of women with and without cervical cancer: the national co-ordinating network for cervical screening working group. Br J Cancer. 1996;73(8):1001-1005.
7. Clavel C, Masure M, Bory JP, et al. Human papillomavirus testing in primary screening for the detection of high-grade cervical lesions: a study of 7932women. Br J Cancer. 2001;84(12):1616-1623. (Pubitemid 32612492)
8. Santoso J, Coleman R, Voet RL, Bernstein S, Lifshitz S, Miller D. Pathology slide review in gynecologic oncology. Obstet Gynecol. 1998;91(5, pt 1):730-734. (Pubitemid 28208865)
9. Creagh T, Bridger J, Kupek E, Fish DE, Martin-Bates E, Wilkins M. Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia. J Clin Pathol. 1995;48(1):59-60.
10. Nelson G, Duggan M, Nation J. Controversy in colposcopic management: a Canadian survey. J Obstet Gynaecol Can. 2006;28(1):36-40.
11. Walboomers J, Jacobs M, Manos M, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189(1):12-19. (Pubitemid 29406813)
12. Cuschieri K, Cubie HA, Whitley M, et al. Persistent high risk HPV infection associated with development of cervical neoplasia in a prospective population study. J Clin Pathol. 2005;58(9):946-950. (Pubitemid 41265279)
13. Syrjanen S, Syrjanen K. New concepts on the role of human papillomavirus in cell cycle regulation. Ann Med. 1999;31(3):175-187. (Pubitemid 29304455)
14. zur Hausen H. Papillomavirus infections - a major cause of human cancers. Biochim Biophys Acta. 1996;1288(2):F55-F78.
15. Graham SV. Late events in the life cycle of human papillomaviruses. In: Campo MS, ed. Papillomavirus Research: From Natural History to Vaccines and Beyond. Norfolk, England: Caister Academic Press; 2006:193-211.
16. McCance D, Kopan R, Fuchs E, Laimins L. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc Natl Acad Sci USA. 1988;85(19):7169-7173. (Pubitemid 18241846)
17. Stoler M, Wolinsky S, Whitbeck A, Broker T, Chow L. Differentiation- linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes. Virology. 1989;172(1):331-340. (Pubitemid 19221458)
18. Stoler M, Rhodes C, Whitbeck A, Wolinsky S, Chow LT, Broker T. Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum Pathol. 1992;23(2):117-128.
19. Demers G, Halbert C, Galloway D. Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene. Virology. 1994;198(1):169-174. (Pubitemid 124018772)
20. Nauenburg S, Zwerschke W, Jansen-Durr P. Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein. FASEB J. 2001;15(3):592-594.
21. Park J, Hwang E, Park S. et al. Physical status and expression of HPV genes in cervical cancers. Gynecol Oncol. 1997;65(1):121-129. (Pubitemid 27171562)
22. Hsu E, McNicol P, Guijon F, Paraskevas M. Quantification of HPV-16 E6-E7 transcription in cervical intraepithelial neoplasia by reverse transcriptase polymerase chain reaction. Int J Cancer. 1993;55(3):397-401. (Pubitemid 23300587)
23. Czeglédy J, Evander M, Hernádi Z, Gergely L, Wadell G. Human papillomavirus type 18 E6* mRNA in primary tumors and pelvic lymph nodes of Hungarian patients with squamous cervical cancer. Int J Cancer. 1994;56(2):182-186. (Pubitemid 24076115)
24. Daniel B, Mukherjee G, Seshadri L, Vallikad E, Krishna S. Changes in the physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analysed by PCR. J Gen Virol. 1995;76(pt 10):2589-2593.
25. Selinka H, Sotlar K, Klingel K, Sauter M, Kandolf R, Bultmann B. Detection of human papillomavirus 16 transcriptional activity in cervical intraepithelial neoplasia grade III lesions and cervical carcinomas by nested reverse transcriptionpolymerase chain reaction and in situ hybridization. Lab Invest. 1998;78(1):9-18. (Pubitemid 28074305)
26. Sotlar K, Selinka H, Menton M, Kandolf R, Bultmann B. Detection of human papillomavirus type 16 E6/E7 oncogene transcripts in dysplastic and nondysplastic cervical scrapes by nested RT-PCR. Gynecol Oncol. 1998;69(2):114-121. (Pubitemid 28246996)
27. Ke L, Adler-Storthz K, Mitchell M, Clayman G, Chen Z. Expression of human papillomavirus E7 mRNA in human oral and cervical neoplasia and cell lines. Oral Oncol. 1999;35(4):415-420. (Pubitemid 29276978)
28. Wang-Johanning F, Lu D, Wang Y, Johnson M, Johanning G. Quantitation of human papillomavirus 16 E6 and E7 DNA and RNA in residual material from thinprep Papanicolaou tests using real-time polymerase chain reaction analysis. Cancer. 2002;94(8):2199-2210. (Pubitemid 34411978)
29. Sotlar K, Stubner A, Diemer D, et al. Detection of high-risk human papillomavirus E6 and E7 oncogene transcripts in cervical scrapes by nested RTpolymerase chain reaction. J Med Virol. 2004;74(1):107-116. (Pubitemid 38988867)
30. Ciotti M, Sesti F, Paba P, et al. Human papillomavirus (HPV) testing in the management of women with abnormal Pap smears: experience of a colposcopy referral clinic. Eur J Gynaecol Oncol. 2004;25(5):577-584. (Pubitemid 39287115)
31. De Roda Husman AM, Walboomers J, Van Den Brule AJ, Meijer C, Snijders P. The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR. J Gen Virol. 1995;76(pt 4):1057-1062.
32. Ylitalo N, Bergstrom T, Gyllensten U. Detection of genital human papil lomavirus by single-tube nested PCR and type-specific oligonucleotide hybridization. J Clin Microbiol. 1995;33(7):1822-1828.
33. Gravitt P, Peyton C, Alessi T, et al. Improved amplification of genital human papillomaviruses. J Clin Microbiol. 2000;38(1):357-361. (Pubitemid 30043317)
34. Goleski V, Dawood M, Smart G, et al. A microsphere based multiplexed assay for genotyping 46 mucosal human Papiloomavirus types. In: Canadian Association of Clinical Microbiologists and Infectious Disease Annual Conference. Hamilton, ON: Canadian Association of Clinical Microbiologists and Infectious Disease; 2007;6. Abstract SP28.
35. Goleski V, Dawood M, Ratnam S, Severini A. Luminex®-based assay for multiplex genotyping of 45 mucosal human papillomavirus types: FC 3a-5. Paper presented at: Eurogin: The 8th International Multidisciplinary Congress - Joining Forces for Cervical Cancer Prevention; November 13, 2008; Nice, France.
36. Bar T, Stahlberg A, Muszta A, Kubista M. Kinetic outlier detection (KOD) in real-time PCR. Nucleic Acids Res. 2003;31(17):e105.
37. Rutledge R, Cote C. Mathematics of quantitative kinetic PCR and the application of standard curves. Nucleic Acids Res. 2003;31(16):e93.
38. Nettleman MD. Receiver operator characteristic (ROC) curves. Infect Control Hosp Epidemiol. 1988;9(8):374-377.
39. Gunnarsson R, Lanke J. The predictive value of microbiologic diagnostic tests if asymptomatic carriers are present. Stat Med. 2002;21(12):1773-1785. (Pubitemid 34678906)
40. Macaskill P, Walter S, Irwig L, Franco E. Assessing the gain in diagnostic performance when combining two diagnostic tests. Stat Med. 2002;21(17):2527-2546. (Pubitemid 34960015)
41. Ostör A. Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol. 1993;12(2):186-192. (Pubitemid 23095196)
42. Andersson S, Hansson B, Norman I, et al. Expression of E6/E7 mRNA from 'high risk' human papillomavirus in relation to CIN grade, viral load and p16INK4a. Int J Oncol. 2006;29(3):705-711.
43. De Boer MA, Jordanova ES, Kenter GG, et al. High human papillomavirus oncogene mRNA expression and not viral DNA load is associated with poor prognosis in cervical cancer patients. Clin Cancer Res. 2007;13(1):132-138.
44. Srodon M, Parry Dilworth H, Ronnett BM. Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion: diagnostic performance, human papillomavirus testing, and follow-up results. Cancer. 2006;108(1):32-38. (Pubitemid 43291241)