A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity

Acta Crystallographica Section D: Biological Crystallography

Volumn 65, Issue 10, 2009, Pages 1118-1125

  Breustedt, Daniel A ^a,b   Chatwell, Lorenz ^a   Skerra, Arne ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

barrel; 1,4 butanediol; Apolipoprotein D; Induced fit; Tear lipocalin; Von Ebners gland protein

Indexed keywords

1,4 BUTANEDIOL; 1,4-BUTANEDIOL; BUTANEDIOL; LCN1 PROTEIN, HUMAN; LIGAND; LIPOCALIN 1;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BUTYLENE GLYCOLS; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; LIPOCALIN 1; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 70349596306     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444909031011     Document Type: Article

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