Site-related white adipose tissue lipid-handling response to oleoyl-estrone treatment in overweight male rats

European Journal of Nutrition

Volumn 48, Issue 5, 2009, Pages 291-299

  Del Mar Romero, María ^a,b   Fernández López, José Antonio ^a,b   Esteve, Montserrat ^a,b   Alemany, Marià ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Lipogenesis; Obesity; Oleoyl estrone; Visceral fat; White adipose tissue

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ANTIOBESITY AGENT; CARNITINE PALMITOYLTRANSFERASE; CD36 ANTIGEN; DNA; ESTRONE OLEATE; FATTY ACID BINDING PROTEIN 4; FATTY ACID SYNTHASE; FATTY ACID TRANSPORTER; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HORMONE SENSITIVE LIPASE; LIPID; LIPOPROTEIN LIPASE; MESSENGER RNA; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ESTRONE; OLEIC ACID; OLEOYL-ESTRONE;

ABDOMINAL SUBCUTANEOUS FAT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL COUNT; CELL LOSS; CELL VOLUME; CONTROLLED STUDY; DNA CONTENT; DNA DETERMINATION; DRUG EFFECT; EPIDIDYMIS; FOOD INTAKE; GENE EXPRESSION; INGUINAL REGION; INTRAABDOMINAL FAT; LIPID ANALYSIS; LIPID STORAGE; LIPID TRANSPORT; LIPOATROPHY; LIPOGENESIS; LIPOLYSIS; MALE; MESENTERY; NONHUMAN; OBESITY; PROTEIN EXPRESSION; RAT; RETROPERITONEUM; RNA ANALYSIS; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE; ANIMAL; BODY COMPOSITION; CALORIC INTAKE; CYTOLOGY; LIPID METABOLISM; METABOLISM; RANDOMIZATION; WISTAR RAT;

RATTUS;

ADIPOSE TISSUE; ANIMALS; ANTI-OBESITY AGENTS; BODY COMPOSITION; ENERGY INTAKE; ESTRONE; GENE EXPRESSION; LIPID METABOLISM; LIPID MOBILIZATION; MALE; OLEIC ACIDS; OVERWEIGHT; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 70349581479     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-009-0013-2     Document Type: Article

References (46)

1. C Adán C Cabot M Esteve MM Grasa R Masanés R Vilà J Estruch JA Fernández-López X Remesar M Alemany 1999 Oleoyl-estrone treatment affects the ponderostat setting differently in lean and obese Zucker rats Int J Obesity 22 366 373 10.1038/sj.ijo.0800828
2. M Alemany JA Fernández-López 2006 Adipose tissue: something more than just adipocytes Curr Nutr Food Sci 2 141 150 10.2174/ 157340106776818817 1:CAS:528:DC%2BD28XkvVWqt7k%3D (Pubitemid 44027821)
3. M Alemany JA Fernández-López A Petrobelli M Granada M Foz X Remesar 2003 Pérdida de peso en un paciente con obesidad mórbida en tratamiento con oleoil-estrona Med Clin (Barc) 121 496 499 10.1157/13053142 (Pubitemid 37411800)
4. M Blay J Peinado-Onsurbe MM Grasa M Díaz-Silva JA Fernández-López X Remesar M Alemany 2002 Effect of oral oleoyl-estrone treatment on plasma lipoproteins and tissue lipase and lipase activities of Zucker lean and obese female rats Int J Obes 26 618 626 10.1038/sj.ijo.0801985 1:CAS:528:DC%2BD38XktlOntb8%3D (Pubitemid 34499280)
5. A Boivin G Brochu S Marceau P Marceau FS Hould A Tchernof 2007 Regional differences in adipose tissue metabolism in obese men Metabolism 56 533 540 10.1016/j.metabol.2006.11.015 1:CAS:528:DC%2BD2sXjsVCjt7w%3D (Pubitemid 46427852)
6. O Bosello M Zamboni 2000 Visceral obesity and metabolic syndrome Obes Rev 1 47 56 10.1046/j.1467-789x.2000.00008.x 1:STN:280:DC%2BD38znsVCqsg%3D%3D
7. C Cabot MM Grasa JA Fernández-López X Remesar M Alemany 2001 Effect of oleoyl-estrone treatment on the expression of β1- β2- and β3-adrenoreceptors in rat adipose tissues Mol Cell Biochem 221 109 115 10.1023/A:1010965527221 1:CAS:528:DC%2BD3MXlvFels7Y%3D (Pubitemid 33640566)
8. Díaz M, Grasa MM, Fernández-López JA, Remesar X, Alemany M (2002) Short-term effects of oleoyl-estrone on insulin sensitivity and glucose disposal in the rat. Int J Obes 26(Suppl 1):S204 (abstract)
9. C Farnier S Krief M Blache F Diot-Dupuy G Mory P Ferre R Bazin 2003 Adipocyte functions are modulated by cell size change: potential involvement of an integrin/ERK signalling pathway Int J Obes 27 1178 1186 10.1038/sj.ijo. 0802399 1:CAS:528:DC%2BD3sXnsF2msrw%3D (Pubitemid 37281665)
10. R Ferrer-Lorente C Cabot JA Fernández-López X Remesar M Alemany 2005 Effects of oleoyl-estrone with dexfenfluramine, sibutramine or phentermine on overweight rats Eur J Pharmacol 513 243 248 10.1016/j.ejphar. 2005.02.044 1:CAS:528:DC%2BD2MXjvVOhsLw%3D (Pubitemid 40616069)
11. M Foretz C Guichard P Ferré F Foufelle 1999 Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis related genes Proc Natl Acad Sci USA 96 1274 12737 10.1073/pnas.96.22.12737 (Pubitemid 29513572)
12. M Guerre-Millo 2002 Adipose tissue hormones J Endocrinol Invest 25 855 861 1:CAS:528:DC%2BD3sXmsFOrsQ%3D%3D
13. MM Grasa C Cabot M Esteve P Yubero RM Masanés M Blay R Vilà J López-Martí JA Fernández-López X Remesar M Alemany 2001 Daily oral oleoyl-estrone gavage induces a dose-dependent loss of fat in Wistar rats Obes Res 9 202 209 10.1038/oby.2001.22 1:CAS:528: DC%2BD3MXktVShur0%3D
14. AS Greenberg WJ Shen K Muliro S Patel SC Souza RA Roth FB Kraemer 2001 Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway J Biol Chem 276 45456 45461 10.1074/jbc. M104436200 1:CAS:528:DC%2BD3MXovFent7k%3D
15. TJ Guzik PJ Marvar M Czesnikiewicz-Guzik R Korbut 2007 Perivascular adipose tissue as a messenger of the brain-vessel axis: role in vascular inflammation and dysfunction J Physiol Pharmacol 58 591 610 1:CAS:528: DC%2BD1cXhtFKkt74%3D
16. RL Hood DC Beitz DJ Best ML Trankina 1983 Relationship between adipocyte size and lipid-synthesis in the Zucker rat Nutr Rep Int 27 791 797 1:CAS:528:DyaL3sXhslOhs7s%3D
17. S Kim N Moustaid-Moussa 2000 Secretory, endocrine and autocrine/paracrine function of the adipocyte J Nutr 130 3110S 3115S 1:CAS:528:DC%2BD3cXptVKlsro%3D
18. GF Lewis M Naples K Uffelman N Leung L Szeto K Adeli 2004 Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian Golden hamsters Endocrinology 145 5006 5012 10.1210/en.2003-1559 1:CAS:528:DC%2BD2cXptVyhtbs%3D (Pubitemid 39551119)
19. YM Liu M Moldes JP Bastard E Bruckert N Viguerie B Hainque A Basdevant D Langin J Pairault K Clement 2004 Adiponutrin: a new gene regulated by energy balance in human adipose tissue J Clin Endocrinol Metab 89 2684 2689 10.1210/jc.2003-031978 1:CAS:528:DC%2BD2cXmtlGqtbs%3D (Pubitemid 38766350)
20. M Palou T Priego J Sánchez E Villegas AM Rodríguez A Palou C Picó 2008 Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting Pflügers Arch Eur J Physiol 456 825 836 10.1007/s00424-008-0461-1 1:CAS:528:DC%2BD1cXnt1alsrg%3D
21. SD Phinney JS Stern KE Burke AB Tang G Miller RT Holman 1994 Human subcutaneous adipose-tissue shows site-specific differences in fatty-acid composition Am J Clin Nutr 60 725 729 1:CAS:528:DyaK2MXitFCnt70%3D
22. CM Pond 2005 Adipose tissue and the immune system Prost Leukotr Essent Fatty Acids 73 17 30 10.1016/j.plefa.2005.04.005 1:CAS:528:DC%2BD2MXlt1Srt70%3D (Pubitemid 40826924)
23. CM Pond CA Mattacks D Sadler 1984 The effects of food restriction and exercise on site-specific differences in adipocyte volume and adipose-tissue cellularity in the guinea-pig 1. Superficial and intra-abdominal sites Br J Nutr 51 415 424 10.1079/BJN19840047 1:STN:280:DyaL2c3gtlCksQ%3D%3D (Pubitemid 14068229)
24. OJ Pykalisto PH Smith JD Brunzell 1975 Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basal- and diet-induced activity J Clin Invest 56 1108 1117 10.1172/JCI108185 1:STN:280:DyaE28%2Fks1Gitw%3D%3D
25. BA Reeder A Senthilselvan JP Després A Angel LY Liu HY Wang SW Rabkin 1997 The association of cardiovascular disease risk factors with abdominal obesity in Canada Can Med Assoc J 157 S39 S45
26. Rat Genome Sequencing Project Consortium 2004 Genome sequence of the Brown Norway rat yields insights into mammalian evolution Nature 428 493 521 10.1038/nature02426 (Pubitemid 38480529)
27. AM Rodriguez C Elabd EZ Amri G Ailhaud C Dani 2005 The human adipose tissue is a source of multipotent stem cells Biochimie 87 125 128 10.1016/j.biochi.2004.11.007 1:CAS:528:DC%2BD2MXhslCntb4%3D (Pubitemid 40298775)
28. X Remesar JA Fernández-López MT Blay P Savall A Salas M Díaz-Silva M Esteve MM Grasa M Alemany 2002 Effect of oral oleoyl-estrone on adipose tissue composition in male rats Int J Obesity 26 1092 1102 10.1038/sj.ijo.0802056 1:CAS:528:DC%2BD38Xmt1Gntb8%3D (Pubitemid 34886292)
29. X Remesar P Guijarro C Torregrosa MM Grasa J López JA Fernández-López M Alemany 2000 Oral oleoyl-estrone induces the rapid loss of body fat in Zucker lean rats fed a hyperlipidic diet Int J Obesity 24 1405 1412 10.1038/sj.ijo.0801393 1:CAS:528:DC%2BD3cXosFymsrw%3D (Pubitemid 30835271)
30. J Ribot MP Portillo C Picó MT Macarulla A Palou 2007 Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet Br J Nutr 97 1074 1082 10.1017/S0007114507682932 1:CAS:528:DC%2BD2sXnt1Gisrg%3D (Pubitemid 46925359)
31. J Ribot AM Rodríguez E Rodríguez A Palou 2008 Adiponectin and resistin response in the onset of obesity in male and female rats Obesity 16 723 730 10.1038/oby.2008.113 1:CAS:528:DC%2BD1cXktVWgt74%3D
32. MM Romero M Esteve M Alemany 2006 Combined effects of oral oleoyl-estrone and limited food intake on body composition of young overweight male rats Int J Obes 30 1149 1156 10.1038/sj.ijo.0803224 1:CAS:528:DC%2BD28XmtFyku7w%3D (Pubitemid 43980587)
33. Romero MM, Esteve M, Fernández-López JA. Lukic T, Harris A, Alemany M (2007) Oleoyl-estrone(OE) regulates lipogenesis in the liver of overweight rats through modulation of ChREBP and SREBPc1. Obesity 15(Suppl.):A116 (abstract)
34. MM Romero MM Grasa M Esteve JA Fernández-López M Alemany 2007 Semiquantitative RT-PCR measurement of gene expression in rat tissues including a correction for varying cell size and number Nutr Metab 4 26 10.1186/1743-7075-4-26 (Pubitemid 351191471)
35. Romero MM, Fernández-López JA, Esteve M, Alemany M (2009) Oleoyl-oestrone inhibits lipogenic, but maintains thermogenic, gene expression of brown adipose tissue in overweight rats. Biosci Rep 29. doi: 10.1042/BSR20080182
36. T Ronti G Lupattelli E Mannarino 2006 The endocrine function of adipose tissue: an update Clin Endocrinol 64 355 365 1:CAS:528:DC%2BD28XkslSrtbc%3D
37. M Rydén J Jocken V van Harmelen A Dicker J Hoffstedt M Wirén L Blomqvist A Mairal D Langin E Blaak P Arner 2007 Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis Am J Physiol 292 E1847 E1855
38. A Salas M Esteve MM Grasa X Remesar 2005 Rats treated with oleoyl-oestrone maintain glucidic homeostasis: comparisons with a pair-fed model Br J Nutr 94 738 745 10.1079/BJN20051547 1:CAS:528:DC%2BD2MXht1yksrzL (Pubitemid 41672379)
39. A Salas X Remesar M Esteve 2007 Oleoyl-estrone treatment activates apoptotic mechanisms in white adipose tissue Life Sci 80 293 298 10.1016/j.lfs.2006.09.025 1:CAS:528:DC%2BD2sXht1Gitw%3D%3D (Pubitemid 44958722)
40. D Sanchis F Balada C Picó MM Grasa J Virgili C Farrerons A Palou JA Fernández-López X Remesar M Alemany 1997 Rats receiving the slimming agent oleoyl-estrone in liposomes (Merlin-2) decrease food intake but maintain thermogenesis Arch Physiol Biochem 105 663 672 10.1076/apab.105.7.663. 11391 1:CAS:528:DyaK1cXlt1eiurY%3D (Pubitemid 28373887)
41. D Sanchis F Balada MM Grasa J Virgili J Peinado C Monserrat JA Fernández-López X Remesar M Alemany 1996 Oleoyl-estrone induces the loss of body fat in rats Int J Obesity 20 588 594 1:CAS:528: DyaK28Xks1Snsr8%3D
42. H Shimano 2002 Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism Vitam Horm 65 167 194 10.1016/S0083-6729(02)65064-2 1:CAS:528:DC%2BD3sXhtVWiurs%3D
43. T Skurk C Alberti-Huber C Herder H Hauner 2007 Relationship between adipocyte size and adipokine expression and secretion J Clin Endocrinol Metab 92 1023 1033 10.1210/jc.2006-1055 1:CAS:528:DC%2BD2sXjtlGmsrc%3D (Pubitemid 46465679)
44. H Tilg AR Moschen 2006 Adipocytokines: mediators linking adipose tissue, inflammation and immunity Nat Rev Immunol 6 772 783 10.1038/nri1937 1:CAS:528:DC%2BD28XhtVSgurnN (Pubitemid 44453463)
45. G van Hall J Büllow M Sacchetti N Al Mulla D Lyngso L Simonsen 2002 Regional fat metabolism in human splanchnic and adipose tissues; the effect of exercise J Physiol 543 1033 1046 10.1113/jphysiol.2002.022392
46. RA Vytasek 1982 A sensitive fluorometric assay for the determination of DNA Anal Biochem 120 243 248 10.1016/0003-2697(82)90342-6 1:CAS:528: DyaL38XhslOhur4%3D