Rats treated with oleoyl-oestrone maintain glucidic homeostasis: Comparisons with a pair-fed model

British Journal of Nutrition

Volumn 94, Issue 5, 2005, Pages 738-745

  Salas, Anna ^a   Esteve, Montserrat ^a   Grasa, M Mar ^a   Remesar, Xavier ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Body weight; Oleoyl oestrone; Pair fed

Indexed keywords

ANTIOBESITY AGENT; ESTRONE OLEATE; GLYCOGEN; SACCHARIN; SUNFLOWER OIL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG MECHANISM; ENERGY CONSUMPTION; FEMALE; FOOD INTAKE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; NONHUMAN; OBESITY; RAT; STARVATION; WEIGHT REDUCTION;

3-HYDROXYBUTYRIC ACID; ADIPONECTIN; ADMINISTRATION, ORAL; ANIMALS; ANTI-OBESITY AGENTS; BLOOD GLUCOSE; CHOLESTEROL; DIETARY FATS, UNSATURATED; EATING; ESTRONE; FEMALE; HOMEOSTASIS; INSULIN; LEPTIN; OLEIC ACIDS; ORGAN SIZE; PLANT OILS; RATS; RATS, WISTAR; TRIGLYCERIDES; WEIGHT LOSS;

ANIMALIA; HELIANTHUS;

EID: 27944507330     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1079/BJN20051547     Document Type: Article

References (24)

1. Adán C, Cabot C, Vilà R, Grasa MM, Masanés RM, Esteve M, Estruch J, Fernández-López JA, Remesar X & Alemany M (1999) Oleoyl-oestrone treatment affects the ponderostat setting differently in lean and obese Zucker rats. Int J Obes 23, 366-373.
2. Ardévol A, Virgili J, Sanchis D, Adán C, Fernández-Real JM, Fernández-López JA, Remesar X & Alemany M (1997) A method for the measurement of plasma oestrone fatty ester levels. Anal Biochem 249, 247-250.
3. Baranowska B, Chmielowska M, Wolinska-Witort E, Roguski K & Wasilewska-Dziubinska E (2001) The relationship between neuropeptides and hormones in starvation. Neuro Endocrinol Let 22, 249-355.
4. Belda X, Ons S, Carrasco J & Armario A (2005) The effects of chronic food restriction on hypothalamic-pituitary-adrenal activity depend on morning versus evening availability of food. Pharmacol Biochem Behav 81, 41-46.
5. Blay M, Peinado-Onsurbe J, Grasa MM, Díaz-Silva M, Fernández-López JA, Remesar X & Alemany M (2002) Effect of oral oleoyl-oestrone treatment on plasma lipoproteins and tissue lipase activities of Zucker lean and obese female rats. Int J Obes 26, 618-626.
6. Cabot C, Grasa MM, Masanés RM, de Matteis R, Cinti S, Fernández-López JA, Remesar X & Alemany M (2001) Oleoyl-oestrone does not have direct estrogenic effects on rats. Life Sci 69, 749-761.
7. Cabot C, Masanés R, Bulló M, García-Lorda P, Fernández-López JA, Salas-Salvadó J & Alemany M (2000) Plasma acyl-oestrone levels are altered in obese women. Endocr Res 26, 465-476.
8. Comizio R, Pietrobelli A, Tan YX, Wang Z, Withers RT, Heymsfield SB & Boozer CN (1998) Total lipid and triglyceride response to energy deficit: relevance to body composition models. Am J Physiol 274, E860-E866.
9. Esteve M, Savall P, Virgili J, Fernández-López JA, Remesar X & Alemany M (2001) Modulation by leptin, insulin and corticosterone of oleoyl-oestrone synthesis in cultured 3T3L1 cells. Biosci Rep 21, 755-763.
10. Fernández-Real JM, Sanchis D, Ricart W, Casamitjana R, Balada F, Remesar X & Alemany M (1999) Plasma ooestrone-fatty acid ester levels are correlated with body fat mass in humans. Clin Endocrinol 50, 253-260.
11. Folch J, Lees M & Sloane-Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226, 497-509.
12. Grasa MM, Cabot C, Esteve M, Yubero P, Masanés RM, Blay MT, Vilà R, López-Martí J, Fernández-López JA, Remesar X & Alemany M (2001) Daily oral oleoyl-oestrone gavage induces a dose-dependent loss of fat in Wistar rats. Obes Res 9, 202-209.
13. Her PA, Hammond RP & Homolsky MW (1973) Sodium pump activity during norepinephrine-stimulated respiration in brown adipocytes. Am J Physiol 224, 1300-1304.
14. Koopman SJ, Sips HC, Bosman J, Radder JK & Krans HM (1989) Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations. Endocrinology 125, 3044-3050.
15. Palou A, Remesar X, Arola L, Herrera E & Alemany M (1981) Metabolic effects of short-term food deprivation in the rat. Hormone Metab Res 13, 326-330.
16. Porter MH, Fine JB, Cutchings AG, Bai Y & DiGirolamo M (2004) Sexual dimorphism in the response of adipose mass and cellularity to graded caloric restriction. Obesity Res 12, 131-140.
17. Rabinovitch A, Grill V, Renold AE & Cerasi E (1976) Insulin release and cyclic AMP accumulation in response to glucose in pancreatic islets of fed and starved rats. J Clin Invest 58, 1209-1216.
18. Remesar X, Fernández-López JA, Blay MT, Savall P, Salas A, Díaz-Silva M, Esteve M, Grasa MM & Alemany M (2002) Effect of oleoyl-oestrone on adipose tissue composition in male rats. Int J Obes 26, 1092-1102.
19. Sanchis D, Adán C, Ardévol A, Grasa MM, Cabot C, Balada F, Vilá R, Estruch J, Puerta M, Fernández-López JA, Remesar X & Alemany M (1997a) Short-term treatment with oleoyl-oestrone in liposomes (Merlin-2) strongly reduces the expression of the ob gene in young rats. Biochem J 326, 357-360.
20. Sanchis D, Balada F, Grasa MM, Virgili J, Peinado J, Monserrat C, Fernández-López JA, Remesar X & Alemany M (1996) Oleoyl-oestrone induces the loss of body fat in rats. Int J Obes 20, 588-594.
21. Sanchis D, Balada F, Picó C, Grasa MM, Virgili J, Farrerons C, Palou A, Fernández-López JA, Remesar X & Alemany M (1997b) Rats receiving the slimming agent Oleoyl-oestrone in liposomes (Merlin-2) decrease food intake but maintain thermogenesis. Archiv Physiol Biochem 105, 663-672.
22. Serafini MT & Alemany M (1987) A micro method for the enzymatic estimation of the degree of glycogen ramification. J Biochem Biophys Meth 15, 33-39.
23. Troyer D & Fernandes G (1996) Nutrition and apoptosis. Nutr Res 16, 1959-1987.
24. Zhang Y, Matheny M, Zolokutukhin S, Tumer N & Scarpace PJ (2002) Regulation of adiponectin and leptin expression in white and brown adipose tissues: influence of beta-3-adrenergic agonists, retinoic acid, leptin and fasting. Biochem Biophys Acta 1584, 115-122.