An introduction to the physics of the bacterial flagellar motor: A nanoscale rotary electric motor

Contemporary Physics

Volumn 50, Issue 6, 2009, Pages 617-632

  Baker, Matthew A B ^a   Berry, Richard M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Biological molecular motors; Nanometre scale devices

Indexed keywords

EID: 70349571983     PISSN: 00107514     EISSN: 13665812     Source Type: Journal    
DOI: 10.1080/00107510903090553     Document Type: Article

References (53)

1. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter, Molecular Biology of the Cell [Book and CD-ROM], Garland Science, London, 2002.
2. S.M. Block, Fifty ways to love your lever: myosin motors, Cell 87 (1996), pp. 151-157.
3. M.A. Geeves and K.C. Holmes, Structural mechanism of muscle contraction, Annu. Rev. Biochem. 68 (1999), pp. 687-728.
4. J.C. Haselgrove, M. Stewart, and H.E. Huxley, Cross-bridge movement during muscle contraction, Nature 261 (1976), pp. 606-608.
5. I.H. Riedel-Kruse, A. Hilfinger, J. Howard, and F. Julicher, How molecular motors shape the flagellar beat, HFSP J. 1 (2007), pp. 192-208.
6. A.I. Tauber, Metchnikoff and the phagocytosis theory, Nat. Rev. Mol. Cell Biol. 4 (2003), pp. 897-901.
7. D.N. Dao, R.H. Kessin, and H.L. Ennis, Developmental cheating and the evolutionary biology of Dictyostelium and Myxococcus, Microbiology 146 (2000), pp. 1505-1512.
8. T.D. Pollard and W.C. Earnshaw, Cell Biology, W.B. Saunders, Kidlington, 2002.
9. D. Cyranoski, Swimming against the tide, Nature 408 (2000), pp. 764-766.
10. C.M. Rosenberger and B.B. Finlay, Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens, Nat. Rev. Mol. Cell Biol. 4 (2003), pp. 385-396.
11. Y. Sowa and R.M. Berry, Bacterial flagellar motor, Q. Rev. Biophys. 41 (2008), pp. 103-132.
12. G.L. Hazelbauer, J.J. Falke, and J.S. Parkinson, Bacterial chemoreceptors: high-performance signaling in networked arrays, Trends Biochem. Sci. 33 (2008), pp. 9-19.
13. V. Sourjik, Receptor clustering and signal processing in E. coli chemotaxis, Trends Microbiol. 12 (2004), pp. 569-576.
14. H.C. Berg, The rotary motor of bacterial flagellar, Annu. Rev. Biochem. 72 (2003), pp. 19-54.
15. S.W. Reid, M.C. Leake, J.H. Chandler, C.L.J.P. Armitage, and R.M. Berry, The maximum number of torque-generating units in the flagellar motor of Escher-ichia coli is at least 11, 103 (2006), pp. 8066-8071.
16. M.C. Leake, J.H. Chandler, G.H. Wadhams, F. Bai, R.M. Berry, and J.P. Armitage, Stoichiometry and turnover in single, functioning membrane protein complexes, Nature 443 (2006), pp. 355-358.
17. R.M. Macnab, How bacteria assemble flagella, Annu. Rev. Microbiol. 57 (2003), pp. 77-100.
18. E.M. Purcell, Life at low Reynolds number, Am. J. Phys. 45 (1977), pp. 3-11.
19. E.M. Sevick, R. Prabhakar, S.R. Williams, and D.J. Searles, Fluctuation theorems, Annu. Rev. Phys. Chem. 59 (2008), pp. 603-633.
20. H. Eyring, The activated complex and the absolute rate of chemical reactions, Chem. Rev. 17 (1935), pp. 65-77.
21. H.A. Kramers, Brownian motion in a field of force and the diffusion model of chemical reactions, Physica 7 (1940), pp. 284-304.
22. A.F. Huxley, Muscle structure and theories of contraction, Prog. Biophys. Biophys. Chem. 7 (1957), pp. 255-318.
23. A.F. Huxley and R.M. Simmons, Proposed mechanism of force generation in striated muscle, Nature 233 (1971), pp. 533-538.
24. H. Noji, R. Yasuda, M. Yoshida, and K. Kinosita, Direct observation of the rotation of F1-ATPase, Nature 386 (1997), pp. 299-302.
25. J.P. Abrahams, A.G.W. Leslie, R. Lutter, and J.E. Walker, Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria, Nature 370 (1994), pp. 621-628.
26. C. Bustamante, D. Keller, and G. Oster, The physics of molecular motors, Acc. Chem. Res. 34 (2001), pp. 412-420.
27. J. Xing, F. Bai, R. Berry, and G. Oster, Torque-speed relationship of the bacterial flagellar motor, Proc. Natl. Acad. Sci. USA 103 (2006), pp. 1260-1265.
28. M. Silverman and M. Simon, Flagellar rotation and the mechanism of bacterial motility, Nature 249 (1974), pp. 73-74.
29. A. Ashkin, J.M. Dziedzic, J.E. Bjorkholm, and S. Chu, Observation of a single-beam gradient force optical trap for dielectric particles, Opt. Lett. 11 (1986), p. 288.
30. F. Gittes and C.F. Schmidt, Interference model for back-focal-plane displacement detection in optical tweezers, Opt. Lett. 23 (1998), pp. 7-9.
31. H. Wang and G. Oster, The Stokes efficiency for molecular motors and its applications, Europhys. Lett. 57 (2002), p. 140.
32. Y. Sowa, A.D. Rowe, M.C. Leake, T. Yakushi, M. Homma, A. Ishijima, and R.M. Berry, Direct observation of steps in rotation of the bacterial flagellar motor, Nature 437 (2005), pp. 916-919.
33. R. Yasuda, H. Noji, M. Yoshida, K. Kinosita, and H. Itoh, Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase, Nature 410 (2001), pp. 898-904.
34. W.S. Ryu, R.M. Berry, and H.C. Berg, Torque-generating units of the flagellar motor of Escherichia coli have a high duty ratio, Nature 403 (2000), pp. 444-447.
35. T. Yorimitsu and M. Homma, Na-driven flagellar motor of Vibrio, Biochim. Biophys. Acta (BBA)-Bioenergetics 1505 (2001), pp. 82-93.
36. Y. Asai, T. Yakushi, I. Kawagishi, and M. Homma, Ion-coupling determinants of Na-driven and H-driven flagellar motors, J. Molec. Biol. 327 (2003), pp. 453-463.
37. C. Lo, M.C. Leake, T. Pilizota, and R.M. Berry, Nonequivalence of membrane voltage and ion-gradient as driving forces for the bacterial flagellar motor at low load, Biophys. J. 93 (2007), pp. 294-302.
38. X. Chen and H.C. Berg, Torque-speed relationship of the flagellar rotary motor of Escherichia coli, Biophys. J. 78 (2000), pp. 1036-1041.
39. Y. Inoue, C. Lo, H. Fukuoka, H. Takahashi, Y. Sowa, T. Pilizota, G.H. Wadhams, M. Homma, R.M. Berry, and A. Ishijima, Torque-Speed relationships of Na-driven chimeric flagellar motors in Escherichia coli, J. Molec. Biol. 376 (2008), pp. 1251-1259.
40. H.C. Berg and L. Turner, Torque generated by the flagellar motor of Escherichia coli, Biophys. J. 65 (1993), pp. 2201-2216.
41. R.M. Berry and H.C. Berg, Torque generated by the flagellar motor of Escherichia coli while driven backward, Biophys. J. 76 (1999), pp. 580-587.
42. X. Chen and H.C. Berg, Solvent-isotope and pH effects on flagellar rotation in Escherichia coli, Biophys. J. 78 (2000), pp. 2280-2284.
43. C.V. Gabel and H.C. Berg, The speed of the flagellar rotary motor of Escherichia coli varies linearly with protonmotive force, Proc. Natl. Acad. Sci. USA 100 (2003), pp. 8748-8751.
44. R.M. Berry and H.C. Berg, Torque generated by the flagellar motor of Escherichia coli while driven backward, Biophys. J. 76 (1999), pp. 580-587.
45. F. Bai, C. Lo, R.M. Berry, and J. Xing, Model studies of the dynamics of bacterial flagellar motors, Biophys. J. 96 (2009), pp. 3154-3167.
46. J. Yuan and H.C. Berg, Resurrection of the flagellar rotary motor near zero load, Proc. Natl. Acad. Sci. 105 (2008), pp. 1182-1185.
47. K. Svoboda, C.F. Schmidt, B.J. Schnapp, and S.M. Block, Direct observation of kinesin stepping by optical trapping interferometry, Nature 365 (1993), pp. 721-727.
48. M.J. Schnitzer, K. Visscher, and S.M. Block, Force production by single kinesin motors, Nat. Cell Biol. 2 (2000), pp. 718-723.
49. T. Pilizota, Y. Sowa, and R.M. Berry, Single molecule studies of rotary molecular motors, in Handbook of Single-Molecule Biophysics, A.M. van Oijen and P. Hinterdorfer, eds., Springer, Berlin, 2009.
50. D.R. Thomas, N.R. Francis, C. Xu, and D.J. DeRosier, The three-dimensional structure of the flagellar rotor from a clockwise-locked mutant of Salmonella enterica Serovar typhimurium, J. Bacteriol. 188 (2006), pp. 7039-7048.
51. A.D. Samuel and H.C. Berg, Fluctuation analysis of rotational speeds of the bacterial flagellar motor, Proc. Natl. Acad. Sci. USA 92 (1995), pp. 3502-3506.
52. A.D. Samuel and H.C. Berg, Torque-generating units of the bacterial flagellar motor step independently, Biophys J. 71 (1996), pp. 918-923.
53. S.M. Block, D.F. Blair, and H.C. Berg, Compliance of bacterial flagella measured with optical tweezers, Nature 338 (1989), pp. 514-518.