A quantitatively-based methodology for the evaluation of chemical hormesis

Human and Ecological Risk Assessment (HERA)

Volumn 3, Issue 4, 1997, Pages 545-554

  Calabrese, Edward J ^a   Baldwin, Linda A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Hormesis; Low dose; Stimulation; U shaped; curve

Indexed keywords

EID: 21944439410     PISSN: 10807039     EISSN: None     Source Type: Journal    
DOI: 10.1080/10807039709383710     Document Type: Article

References (8)

1. REFERENCES Calabrese, E.J. 1994. Primer on BELLE. In: Biological Effects of Low Level Exposures: DoseResponse Relationships, pp. 27-42. (Calabrese, E.J., Ed.). Boca Raton, CRC/Lewis Publishers.
2. Calabrese, E.J. and Baldwin, L.A. 1997. The dose determines the stimulation (and poison): development of a chemical hormesis database. Int. J. Toxicol. In Press.
3. Calabrese, E.J., McCarthy, M., and Kenyon, E. 1987. The occurrence of chemical hormesis. Health Physics 57, 531-54.
4. Davis, J.M. and Svensgaard, D.J. 1994. Nonmonotonic dose-response relationships in toxicological studies. In: Biological Effects of Low Level Exposures: Dose-Response Relationships, pp. 67-86. (Calabrese, E.J., Ed.). Boca Raton, CRC/Lewis Publishers.
5. Luckey, T.D. 1975. Suppl. to Vol. 1 of Environmental Quality and Safety. In: Heavy Metal Toxicity, Safety, and Hormology, pp. 83-103. (Luckey, T.D., Venugopal, B., and Hutcheson, D., Eds.). Stuttgart, Georg Thieme.
6. Schulz, H. 1888. Pfugers Atch. Ges. Physiol. 42, 517.
7. Stebbing, A.R.D. 1982. Hormesis-The stimulation of growth by low levels of inhibitors. Sci. Total Environ. 22, 213-234.
8. Townsend, J.F. and Luckey, T.D. 1960. Hormoligosis in pharmacology. J. Am. Med. Assoc. 173, 44-48.