-
1
-
-
33748652419
-
What is the right dose? The elusive optimal biologic dose in phase I clinical trials
-
Adjei AA. 2006. What is the right dose? The elusive optimal biologic dose in phase I clinical trials. Journal of Clinical Oncology 24(25):4054-4055.
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.25
, pp. 4054-4055
-
-
Adjei, A.A.1
-
2
-
-
34247159023
-
Cell mechanics and stress: From molecular details to the "universal cell reaction" and hormesis
-
Agutter PS. 2007. Cell mechanics and stress: from molecular details to the "universal cell reaction" and hormesis. BioEssays 29:324-333.
-
(2007)
BioEssays
, vol.29
, pp. 324-333
-
-
Agutter, P.S.1
-
3
-
-
33745791335
-
Low-dose metronomic chemotherapy: Myth or truth?
-
Baruchel S and Stempak D, 2006. Low-dose metronomic chemotherapy: Myth or Truth? Onkologie. 29:305-307.
-
(2006)
Onkologie
, vol.29
, pp. 305-307
-
-
Baruchel, S.1
Stempak, D.2
-
4
-
-
33645000934
-
A dual and opposite effect of calendula officinalis flower extract:chemoprotector and promoter in rat hepatocarcinogenesis model
-
Barajas-Farias LM, Pérez-Carreón JI, Arce-Popoca E, Fattel-Fazenda S, Alemán-Lazarini L, Hernández-García S, Salcido-Neyoy M, Cruz-Jiménez FG, Camacho J, Villa-Treviño S. 2006. A dual and opposite effect of calendula officinalis flower extract: chemoprotector and promoter in rat hepatocarcinogenesis model, Planta Med;72:217-221.
-
(2006)
Planta Med
, vol.72
, pp. 217-221
-
-
Barajas-Farias, L.M.1
Pérez-Carreón, J.I.2
Arce-Popoca, E.3
Fattel-Fazenda, S.4
Alemán-Lazarini, L.5
Hernández-García, S.6
Salcido-Neyoy, M.7
Cruz-Jiménez, F.G.8
Camacho, J.9
Villa-Treviño, S.10
-
5
-
-
0041589524
-
Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells
-
Bertolini F, Paul S, Mancuso P, Monestiroli S, Gobbi A, Shaked Y, Kerbel RS. 2003. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells. Cancer Research 63:4342-4346.
-
(2003)
Cancer Research
, vol.63
, pp. 4342-4346
-
-
Bertolini, F.1
Paul, S.2
Mancuso, P.3
Monestiroli, S.4
Gobbi, A.5
Shaked, Y.6
Kerbel, R.S.7
-
6
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
-
Bocci G, Nicolaou KC, Kerbel RS. 2002. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Research 62:6938-6943.
-
(2002)
Cancer Research
, vol.62
, pp. 6938-6943
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.S.3
-
7
-
-
23844483271
-
Cyclophosphamide-methotrexate "metronomic" chemotherapy for the palliative treatment of metastatic cancer. A comparative pharmacoeconomic evaluation
-
Bocci G, Tuccori M, Emmenegger U, Liguori V, Falcone A, Kerbel RS, and Del Tacca M. 2005. Cyclophosphamide-methotrexate "metronomic" chemotherapy for the palliative treatment of metastatic cancer. A comparative pharmacoeconomic evaluation. Ann Oncol 16:1243-1252.
-
(2005)
Ann Oncol
, vol.16
, pp. 1243-1252
-
-
Bocci, G.1
Tuccori, M.2
Emmenegger, U.3
Liguori, V.4
Falcone, A.5
Kerbel, R.S.6
Del Tacca, M.7
-
8
-
-
4444383982
-
The economics of cancer care in the UK
-
Bosanquet N, Sikora K. 2004. The economics of cancer care in the UK. Lancet Oncol 5:568-574.
-
(2004)
Lancet Oncol
, vol.5
, pp. 568-574
-
-
Bosanquet, N.1
Sikora, K.2
-
9
-
-
2342565251
-
Less is more
-
Brower V. 2003. Less is more. EMBO 4(9):831-834.
-
(2003)
EMBO
, vol.4
, Issue.9
, pp. 831-834
-
-
Brower, V.1
-
10
-
-
0031956731
-
Hormesis as a biological hypothesis
-
Calabrese EJ, Baldwin LA. 1998. Hormesis as a biological hypothesis. Environ Health Perspect 106(Suppl 1):357-362.
-
(1998)
Environ Health Perspect
, vol.106
, Issue.SUPPL. 1
, pp. 357-362
-
-
Calabrese, E.J.1
Baldwin, L.A.2
-
11
-
-
22544476468
-
Paradigm lost, paradigm found: The re-emergence of hormesis as a fundamental dose response model in the toxicological sciences
-
Calabrese EJ, 2004. Paradigm lost, paradigm found: The re-emergence of hormesis as a fundamental dose response model in the toxicological sciences. Environmental Pollution. 138:378-411
-
(2004)
Environmental Pollution
, vol.138
, pp. 378-411
-
-
Calabrese, E.J.1
-
12
-
-
12844251475
-
The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: An overview
-
Calabrese EJ, and Blain R. 2005. The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview, Toxicology and Applied Pharmacology 202:289-301.
-
(2005)
Toxicology and Applied Pharmacology
, vol.202
, pp. 289-301
-
-
Calabrese, E.J.1
Blain, R.2
-
13
-
-
34250844410
-
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework
-
Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC, Clarkson TW, Cook RR, Diamond DD, Doolittle DJ, Dorato MA, Duke SO, Feinendegen L, Gardner DE, Hart RW, Hastings KL, Hayes AW, Hoffmann GR, Ives JA, Jaworowski Z, Johnson TE, Jonas WB, Kaminski NE, Keller JG, Klaunig JE, Knudsen TB, Kozumbo WJ, Lettieri T, Liu S-Z, Maisseu A, Maynard KI, Masoro EJ, McClellan RO, Mehendale HM, Mothersill C, Newlin D, Nigg HN, Oehme FW, Phalen RF, Philbert MA, Rattan SIS, Riviere JE, Rodricks J, Sapolsky RM, Scott BR, Seymour C, Sinclair DA, Smith-Sonneborn J, Snow ET, Spear L, Stevenson DE, Thomas Y, Tubiana M, Williams GM, Mattson MP. 2007. Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl. Pharmacol. 222(1):122-128.
-
(2007)
Toxicol. Appl. Pharmacol
, vol.222
, Issue.1
, pp. 122-128
-
-
Calabrese, E.J.1
Bachmann, K.A.2
Bailer, A.J.3
Bolger, P.M.4
Borak, J.5
Cai, L.6
Cedergreen, N.7
Cherian, M.G.8
Chiueh, C.C.9
Clarkson, T.W.10
Cook, R.R.11
Diamond, D.D.12
Doolittle, D.J.13
Dorato, M.A.14
Duke, S.O.15
Feinendegen, L.16
Gardner, D.E.17
Hart, R.W.18
Hastings, K.L.19
Hayes, A.W.20
Hoffmann, G.R.21
Ives, J.A.22
Jaworowski, Z.23
Johnson, T.E.24
Jonas, W.B.25
Kaminski, N.E.26
Keller, J.G.27
Klaunig, J.E.28
Knudsen, T.B.29
Kozumbo, W.J.30
Lettieri, T.31
Liu, S.-Z.32
Maisseu, A.33
Maynard, K.I.34
Masoro, E.J.35
McClellan, R.O.36
Mehendale, H.M.37
Mothersill, C.38
Newlin, D.39
Nigg, H.N.40
Oehme, F.W.41
Phalen, R.F.42
Philbert, M.A.43
Rattan, S.I.S.44
Riviere, J.E.45
Rodricks, J.46
Sapolsky, R.M.47
Scott, B.R.48
Seymour, C.49
Sinclair, D.A.50
Smith-Sonneborn, J.51
Snow, E.T.52
Spear, L.53
Stevenson, D.E.54
Thomas, Y.55
Tubiana, M.56
Williams, G.M.57
Mattson, M.P.58
more..
-
14
-
-
34447330451
-
Threshold-dose-response model-RIP: 1911 to 2006
-
Calabrese EJ. 2007. Threshold-dose-response model-RIP: 1911 to 2006. Bioessays 29:686-688.
-
(2007)
Bioessays
, vol.29
, pp. 686-688
-
-
Calabrese, E.J.1
-
15
-
-
7344247122
-
Proposition: Radiation hormesis should be elevated to a position of scientific respectability
-
Cameron JR and Moulder JE, 1998. Proposition: Radiation hormesis should be elevated to a position of scientific respectability. Medical Physics. 25(8).1407-1410.
-
(1998)
Medical Physics
, vol.25
, Issue.8
, pp. 1407-1410
-
-
Cameron, J.R.1
Moulder, J.E.2
-
16
-
-
70349318947
-
Effects of cobalt-60 exposure on the health of Taiwan residents suggest new approach needed in radiation protection
-
Chen WL, Luan YC, Shieh MC, Chen ST, Kung HT, Soong KL, Yeh YC, Chou TS, Mong SH, Wu JT, Sun CP, Deng WP, Wu MF, Shen ML. 2006. Effects of cobalt-60 exposure on the health of Taiwan residents suggest new approach needed in radiation protection. Dose Response. 5(1):63-75.
-
(2006)
Dose Response
, vol.5
, Issue.1
, pp. 63-75
-
-
Chen, W.L.1
Luan, Y.C.2
Shieh, M.C.3
Chen, S.T.4
Kung, H.T.5
Soong, K.L.6
Yeh, Y.C.7
Chou, T.S.8
Mong, S.H.9
Wu, J.T.10
Sun, C.P.11
Deng, W.P.12
Wu, M.F.13
Shen, M.L.14
-
17
-
-
0036194583
-
Cancer economics: On variations in the costs of treating cancer
-
Chirikos TN. 2002. Cancer economics: on variations in the costs of treating cancer. Cancer Control 9:59-66.
-
(2002)
Cancer Control
, vol.9
, pp. 59-66
-
-
Chirikos, T.N.1
-
18
-
-
23844503953
-
Treatment of advanced breast cancer: The good, the bad and the ugly
-
Colleoni M, Gelber S, and Goldhirsch A. 2005. Treatment of advanced breast cancer: the good, the bad and the ugly. Ann Oncol 16:1219-1221.
-
(2005)
Ann Oncol
, vol.16
, pp. 1219-1221
-
-
Colleoni, M.1
Gelber, S.2
Goldhirsch, A.3
-
19
-
-
31544441697
-
Metronomic low-dose oral cyclophos-phamide and methotrexate plus or minus thalidomide in metastatic breast cancer: Antitumor activity and biological effects
-
Colleoni M, Orlando L, Sanna G, Rocca A, Maisonneuve P, Peruzzotti G, Ghisini R, Sandri MT, Zorzino L, Nole F, Viale G and Goldhirsch A. 2006. Metronomic low-dose oral cyclophos-phamide and methotrexate plus or minus thalidomide in metastatic breast cancer: antitumor activity and biological effects, Annals of Oncology 17:232-238.
-
(2006)
Annals of Oncology
, vol.17
, pp. 232-238
-
-
Colleoni, M.1
Orlando, L.2
Sanna, G.3
Rocca, A.4
Maisonneuve, P.5
Peruzzotti, G.6
Ghisini, R.7
Sandri, M.T.8
Zorzino, L.9
Nole, F.10
Viale, G.11
Goldhirsch, A.12
-
21
-
-
70349305925
-
Health effects of low level radiation: When will we acknowledge the reality?
-
Cuttler JM. 2007. Health effects of low level radiation: when will we acknowledge the reality? Dose-Response 5:292-298.
-
(2007)
Dose-Response
, vol.5
, pp. 292-298
-
-
Cuttler, J.M.1
-
23
-
-
85184375885
-
Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity
-
2005. V. R. Rozados et al.
-
De Pas T, Colleoni M, Orlando L, Masci G, Rocca A, Catania C, Curigliano G, Manzoni S, Goldhirsch A, and de Braud F. 2005. Reply to the article "Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity" by V. R. Rozados et al. Ann Oncol 2004;15: 543-1550)
-
(2004)
Ann Oncol
, vol.15
, pp. 543-1550
-
-
De Pas, T.1
Colleoni, M.2
Orlando, L.3
Masci, G.4
Rocca, A.5
Catania, C.6
Curigliano, G.7
Manzoni, S.8
Goldhirsch, A.9
De Braud, F.10
-
24
-
-
85184360776
-
... and in humans?
-
... and in humans? Annals of Oncology 16: 673-677.
-
Annals of Oncology
, vol.16
, pp. 673-677
-
-
-
25
-
-
32944458087
-
Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts
-
duManoir JM, Francia G, Man S, Mossoba M, Medin JA, Viloria-Petit A, Hicklin DJ, Emmenegger U, Kerbel RS. 2006. Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. Clin Cancer Res 12(3):904-916.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.3
, pp. 904-916
-
-
Du Manoir, J.M.1
Francia, G.2
Man, S.3
Mossoba, M.4
Medin, J.A.5
Viloria-Petit, A.6
Hicklin, D.J.7
Emmenegger, U.8
Kerbel, R.S.9
-
26
-
-
2542539735
-
A comparative analysis of low-dose metronomic cyclophosphamide reveals absent or low-grade toxicity on tissues highly sensitive to the toxic effects of maximum tolerated dose regimens
-
Emmenegger U, Man S, Shaked Y, Francia G, Wong JW, Hicklin DJ, Kerbel RS. 2004. A comparative analysis of low-dose metronomic cyclophosphamide reveals absent or low-grade toxicity on tissues highly sensitive to the toxic effects of maximum tolerated dose regimens. Cancer Research 64:3994-4000.
-
(2004)
Cancer Research
, vol.64
, pp. 3994-4000
-
-
Emmenegger, U.1
Man, S.2
Shaked, Y.3
Francia, G.4
Wong, J.W.5
Hicklin, D.J.6
Kerbel, R.S.7
-
27
-
-
0141988568
-
Fundamental concepts of the angiogenic process
-
Folkman J. 2003. Fundamental concepts of the angiogenic process. Current Molecular Medicine 3:643-651.
-
(2003)
Current Molecular Medicine
, vol.3
, pp. 643-651
-
-
Folkman, J.1
-
28
-
-
34248562373
-
Antiangiogenic metronomic chemotherapy and hyperthermia in the palliation of advanced cancer
-
Franchi F, Grassi P, Ferro D, Pigliucci G, De Chicchis M, Castigliani G, Pastore C, and Seminara P. 2007. Antiangiogenic metronomic chemotherapy and hyperthermia in the palliation of advanced cancer. European Journal of Cancer Care 16:258-262.
-
(2007)
European Journal of Cancer Care
, vol.16
, pp. 258-262
-
-
Franchi, F.1
Grassi, P.2
Ferro, D.3
Pigliucci, G.4
De Chicchis, M.5
Castigliani, G.6
Pastore, C.7
Seminara, P.8
-
29
-
-
33646447206
-
Clinical pharmacokinetic study of arsenic trioxide in an acute promyelocytic leukemia (APL) patient: Speciation of arsenic metabolites in serum and urine
-
May
-
Fukai Y, Hirata M, Ueno M, Ichikawa N, Kobayashi H, Saitoh H, Sakurai T, Kinoshita K, Kaise T, Ohta S., 2006. Clinical pharmacokinetic study of arsenic trioxide in an acute promyelocytic leukemia (APL) patient: speciation of arsenic metabolites in serum and urine. Biol Pharm Bull. May;29(5):1022-1027.
-
(2006)
Biol Pharm Bull.
, vol.29
, Issue.5
, pp. 1022-1027
-
-
Fukai, Y.1
Hirata, M.2
Ueno, M.3
Ichikawa, N.4
Kobayashi, H.5
Saitoh, H.6
Sakurai, T.7
Kinoshita, K.8
Kaise, T.9
Ohta, S.10
-
30
-
-
37849035249
-
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital Phase II Consortia
-
Garcia AA, Hirte H, Fleming G, Yang D, Tsao-Wei DD, Roman L, Groshen S, Swenson S, Markland F, Gandara D, Scudder S, Morgan R, Chen H, Lenz HJ, Oza AM. 2008. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital Phase II Consortia, J Clin Oncol 26:76-82.
-
(2008)
J Clin Oncol
, vol.26
, pp. 76-82
-
-
Garcia, A.A.1
Hirte, H.2
Fleming, G.3
Yang, D.4
Tsao-Wei, D.D.5
Roman, L.6
Groshen, S.7
Swenson, S.8
Markland, F.9
Gandara, D.10
Scudder, S.11
Morgan, R.12
Chen, H.13
Lenz, H.J.14
Oza, A.M.15
-
31
-
-
0031406307
-
Antiangiogenic drugs as a novel anticancer therapeutic strategy Which are the more promising agents? What are the clinical developments and indications?
-
Gasparini G. 1997. Antiangiogenic drugs as a novel anticancer therapeutic strategy Which are the more promising agents? What are the clinical developments and indications? Critical Reviews in Oncology: Hematology 26:147-162.
-
(1997)
Critical Reviews in Oncology: Hematology
, vol.26
, pp. 147-162
-
-
Gasparini, G.1
-
32
-
-
0035214416
-
Metronomic scheduling: The future of chemotherapy?
-
Gasparini G. 2001. Metronomic scheduling: the future of chemotherapy? Lancet Oncol; 2:733-740.
-
(2001)
Lancet Oncol
, vol.2
, pp. 733-740
-
-
Gasparini, G.1
-
33
-
-
0034048358
-
Less is more, regularly: Metronomic dosing of cyto-toxic drugs can target tumor angiogenesis in mice
-
Hanahan D, Bergers G, and Bergsland E. 2000. Less is more, regularly: metronomic dosing of cyto-toxic drugs can target tumor angiogenesis in mice. The Journal of Clinical Investigation 105(8):1045-1047.
-
(2000)
The Journal of Clinical Investigation
, vol.105
, Issue.8
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
34
-
-
33746336530
-
A new extract of the plant Calendula officinalis produces a dual in vitro effect: Cytotoxic anti-tumor activity and lymphocyte activation
-
Jiménez-Medina E, Garcia-Lora A, Paco L, Algarra I, Collado A, Garrido F. 2006. A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation. BMC Cancer. 5:1-14.
-
(2006)
BMC Cancer
, vol.5
, pp. 1-14
-
-
Jiménez-Medina, E.1
Garcia-Lora, A.2
Paco, L.3
Algarra, I.4
Collado, A.5
Garrido, F.6
-
35
-
-
33846441659
-
Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer
-
Kamat AA, Kim TJ, Landen CN Jr., Lu C, Han LY, Lin YG, Merritt WM, Thaker PH, Gershenson DM, Bischoff FZ, Heymach JV, Jaffe RB, Coleman RL, Sood AK. 2007. Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer. Cancer Res. 67(1):281-288.
-
(2007)
Cancer Res.
, vol.67
, Issue.1
, pp. 281-288
-
-
Kamat, A.A.1
Kim, T.J.2
Landen Jr., C.N.3
Lu, C.4
Han, L.Y.5
Lin, Y.G.6
Merritt, W.M.7
Thaker, P.H.8
Gershenson, D.M.9
Bischoff, F.Z.10
Heymach, J.V.11
Jaffe, R.B.12
Coleman, R.L.13
Sood, A.K.14
-
36
-
-
33745651419
-
Metronomic therapy from a pharmacologist's view
-
Kamen BA, Glod J, Cole PD. 2006. Metronomic therapy from a pharmacologist's view. J Pediatr Hematol Oncol 28(6):325-327.
-
(2006)
J Pediatr Hematol Oncol
, vol.28
, Issue.6
, pp. 325-327
-
-
Kamen, B.A.1
Glod, J.2
Cole, P.D.3
-
37
-
-
0034243694
-
High-time chemotherapy or high time for low dose
-
Kamen BA, Rubin E, Aisner J, and Glatstein E. 2000. High-time chemotherapy or high time for low dose. Journal of Clinical Oncology 18(16):2935-2937.
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.16
, pp. 2935-2937
-
-
Kamen, B.A.1
Rubin, E.2
Aisner, J.3
Glatstein, E.4
-
38
-
-
28144461113
-
Metronomic therapy it makes sense and is patient friendly
-
Kamen BA. 2005. Metronomic therapy it makes sense and is patient friendly. J Pediatr Hematol Oncol. 27:571-572.
-
(2005)
J Pediatr Hematol Oncol
, vol.27
, pp. 571-572
-
-
Kamen, B.A.1
-
39
-
-
0036225444
-
Continuous low-dose antiangiogenic metronomic chemotherapy: From the research laboratory into the oncology clinic
-
Kerbel RS, Klement G, Prithard KI and Kamen B. 2002. Continuous low-dose antiangiogenic metronomic chemotherapy: from the research laboratory into the oncology clinic. Annals of Oncology 13:12-15.
-
(2002)
Annals of Oncology
, vol.13
, pp. 12-15
-
-
Kerbel, R.S.1
Klement, G.2
Prithard, K.I.3
Kamen, B.4
-
41
-
-
33646267928
-
From total empiricism to a rational design of metronomic chemotherapy phase I dosing trials
-
Lam T, Hetherington JW, Greenman J, and Maraveyas A. 2006. From total empiricism to a rational design of metronomic chemotherapy phase I dosing trials, Anti-Cancer Drugs 17:113-121.
-
(2006)
Anti-Cancer Drugs
, vol.17
, pp. 113-121
-
-
Lam, T.1
Hetherington, J.W.2
Greenman, J.3
Maraveyas, A.4
-
42
-
-
33745936962
-
Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice
-
Liu B, Pan S, Dong X, Qiao H, Jiang H, Krissansen GW and Sun X. 2006. Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice. Cancer Sci. 97:675-681.
-
(2006)
Cancer Sci.
, vol.97
, pp. 675-681
-
-
Liu, B.1
Pan, S.2
Dong, X.3
Qiao, H.4
Jiang, H.5
Krissansen, G.W.6
Sun, X.7
-
43
-
-
24644524733
-
Nonlinearity and thresholds in dose-response relationships for carcinogenicity due to sampling variation, logarithmic dose scaling, or small differences in individual susceptibility
-
Lutz WK, Gaylor DW, Conolly RB, Lutz RW. 2005. Nonlinearity and thresholds in dose-response relationships for carcinogenicity due to sampling variation, logarithmic dose scaling, or small differences in individual susceptibility. Toxicology and Applied Pharmacology 207:S565 - S569.
-
(2005)
Toxicology and Applied Pharmacology
, vol.207
-
-
Lutz, W.K.1
Gaylor, D.W.2
Conolly, R.B.3
Lutz, R.W.4
-
44
-
-
20444433198
-
In vitro proco-agulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: Modulation by lower-dose chemotherapy
-
Ma L, Francia G, Viloria-Petit A, Hicklin DJ, du Manoir J, Rak J, Kerbel RS. 2005. In vitro proco-agulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: modulation by lower-dose chemotherapy. Cancer Res 65(12):5365-5373.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5365-5373
-
-
Ma, L.1
Francia, G.2
Viloria-Petit, A.3
Hicklin, D.J.4
Du Manoir, J.5
Rak, J.6
Kerbel, R.S.7
-
46
-
-
0037093209
-
Antitumor effects in mice of low-dose (Metronomic) cyclophosphamide administered continuously through the drinking water
-
Man S, Bocci G, Francia G, Green SK, Jothy S, Hanahan D, Bohlen P, Hicklin DJ, Bergers G, Kerbel RS. 2002. Antitumor effects in mice of low-dose (Metronomic) cyclophosphamide administered continuously through the drinking water. Cancer Research. 62:2731-2735.
-
(2002)
Cancer Research
, vol.62
, pp. 2731-2735
-
-
Man, S.1
Bocci, G.2
Francia, G.3
Green, S.K.4
Jothy, S.5
Hanahan, D.6
Bohlen, P.7
Hicklin, D.J.8
Bergers, G.9
Kerbel, R.S.10
-
47
-
-
33745939679
-
Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy
-
Mancuso P, Colleoni M, Calleri A, Orlando L, Maisonneuve P, Pruneri G, Agliano A, Goldhirsch A, Shaked Y, Kerbel RS, and Bertolini F. 2006. Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy, Blood 108:452-459.
-
(2006)
Blood
, vol.108
, pp. 452-459
-
-
Mancuso, P.1
Colleoni, M.2
Calleri, A.3
Orlando, L.4
Maisonneuve, P.5
Pruneri, G.6
Agliano, A.7
Goldhirsch, A.8
Shaked, Y.9
Kerbel, R.S.10
Bertolini, F.11
-
48
-
-
18944379083
-
Letter to the Editor: Can a rational design for metronomic chemotherapy dosing be devised?
-
Maraveyas A, Lam T, Hetherington JW, and Greenman J. 2005. Letter to the Editor: Can a rational design for metronomic chemotherapy dosing be devised? British Journal of Cancer 92:1588-1590.
-
(2005)
British Journal of Cancer
, vol.92
, pp. 1588-1590
-
-
Maraveyas, A.1
Lam, T.2
Hetherington, J.W.3
Greenman, J.4
-
49
-
-
33750159449
-
Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses
-
Mattson MP, and Cheng A. 2006. Neurohormetic phytochemicals: low-dose toxins that induce adaptive neuronal stress responses. Trends in Neurosciences 29(11):632-639.
-
(2006)
Trends in Neurosciences
, vol.29
, Issue.11
, pp. 632-639
-
-
Mattson, M.P.1
Cheng, A.2
-
50
-
-
2342492396
-
Commentary: Recent translational research: Antiangiogenic therapy for breast cancer - Where do we stand?
-
Miller KD. 2004. Commentary: Recent translational research: antiangiogenic therapy for breast cancer - where do we stand? Breast Cancer Res 6:128-132.
-
(2004)
Breast Cancer Res
, vol.6
, pp. 128-132
-
-
Miller, K.D.1
-
51
-
-
33645744835
-
Highly efficacious non-toxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT cyclophosphamide metronomic chemotherapy
-
Munoz R, Man S, Shaked Y, Lee CR, Wong J, Francia G, Kerbel RS. 2006 Highly efficacious non-toxic preclinical treatment for advanced metastatic breast cancer using combination oral UFT cyclophosphamide metronomic chemotherapy. Cancer Res 66(7):3386-3391.
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3386-3391
-
-
Munoz, R.1
Man, S.2
Shaked, Y.3
Lee, C.R.4
Wong, J.5
Francia, G.6
Kerbel, R.S.7
-
52
-
-
28044436491
-
Anti-angiogenic treatment of breast cancer using metronomic low-dose chemotherapy
-
Munoz R, Shakeda Y, Bertolinic F, Emmeneggera U, Mana S, Kerbel RS. 2005. Anti-angiogenic treatment of breast cancer using metronomic low-dose chemotherapy, The Breast. 14:466-479.
-
(2005)
The Breast
, vol.14
, pp. 466-479
-
-
Munoz, R.1
Shakeda, Y.2
Bertolinic, F.3
Emmeneggera, U.4
Mana, S.5
Kerbel, R.S.6
-
53
-
-
34247136838
-
Hormesis and its place in non monotonic dose-response relationship: Some scientific reality checks
-
Mushak P. 2007. Hormesis and its place in non monotonic dose-response relationship: some scientific reality checks. Environ Health Prespect. 115:500-506.
-
(2007)
Environ Health Prespect
, vol.115
, pp. 500-506
-
-
Mushak, P.1
-
54
-
-
0037842185
-
Mathematics and oncology: A match for life?
-
Piccart-Gebhart MJ. 2003. Mathematics and oncology: A match for life? Journal of Clinical Oncology 21(8):1425-1428.
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.8
, pp. 1425-1428
-
-
Piccart-Gebhart, M.J.1
-
55
-
-
85184355402
-
The medical community must investigate broader use of positron emission tomography to maximize its treatment-planning capabilities
-
Rost EC., 2008. The medical community must investigate broader use of positron emission tomography to maximize its treatment-planning capabilities. Enterprise Imaging and Therapeutic Radiology Management 18(3):44-47.
-
(2008)
Enterprise Imaging and Therapeutic Radiology Management
, vol.18
, Issue.3
, pp. 44-47
-
-
Rost, E.C.1
-
56
-
-
6944241246
-
Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity
-
Rozados VR, Sanchez AM, Gervasoni SI, Berra HH, Matar P, Scharovsky OG. 2004. Metronomic therapy with cyclophosphamide induces rat lymphoma and sarcoma regression, and is devoid of toxicity. Annals of Oncology 15:1543-1550.
-
(2004)
Annals of Oncology
, vol.15
, pp. 1543-1550
-
-
Rozados, V.R.1
Sanchez, A.M.2
Gervasoni, S.I.3
Berra, H.H.4
Matar, P.5
Scharovsky, O.G.6
-
57
-
-
4444376000
-
Noise, stress and annoyance
-
Rylander R. 2004. Noise, stress and annoyance. J Sound Vibr 277:471-478.
-
(2004)
J Sound Vibr
, vol.277
, pp. 471-478
-
-
Rylander, R.1
-
58
-
-
33745590419
-
Homeopathic drug standardization
-
Satti, JA. 2005. Homeopathic Drug Standardization. Semin Integr Med 3(4):113-122.
-
(2005)
Semin Integr Med
, vol.3
, Issue.4
, pp. 113-122
-
-
Satti, J.A.1
-
59
-
-
23844538059
-
Low-dose metronomic combined with intermittent bolus dose cyclophos-phamide is an effective long-term chemotherapy treatment strategy
-
Shaked Y, Emmenegger U, Francia G, Chen L, Lee CR, Man S, Paraghamian A, Ben-David Y, Kerbel RS. 2005a. Low-dose metronomic combined with intermittent bolus dose cyclophos-phamide is an effective long-term chemotherapy treatment strategy. Cancer Res 65(16):7045-7051.
-
(2005)
Cancer Res
, vol.65
, Issue.16
, pp. 7045-7051
-
-
Shaked, Y.1
Emmenegger, U.2
Francia, G.3
Chen, L.4
Lee, C.R.5
Man, S.6
Paraghamian, A.7
Ben-David, Y.8
Kerbel, R.S.9
-
60
-
-
27644436870
-
Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangio-genic activity
-
Shaked Y, Emmenegger U, Man S, Cervi D, Bertolini F, Ben-David Y, Kerbel RS. 2005b. Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangio-genic activity. Blood 106:3058-3061.
-
(2005)
Blood
, vol.106
, pp. 3058-3061
-
-
Shaked, Y.1
Emmenegger, U.2
Man, S.3
Cervi, D.4
Bertolini, F.5
Ben-David, Y.6
Kerbel, R.S.7
-
61
-
-
11444266441
-
Cancer anti-angiogenic therapy
-
Shimizu K and Oku N. 2004. Cancer anti-angiogenic therapy. Biol. Pharm. Bull. 27(5):599-605.
-
(2004)
Biol. Pharm. Bull.
, vol.27
, Issue.5
, pp. 599-605
-
-
Shimizu, K.1
Oku, N.2
-
62
-
-
24644459501
-
Arsenic, mode of action at biologically plausible low doses: What are the implications for low dose cancer risk?
-
Snow ET, Sykora P, Durham TR, Klein CB. 2005. Arsenic, mode of action at biologically plausible low doses: What are the implications for low dose cancer risk? Toxicology and Applied Pharmacology 207:S557 - S564.
-
(2005)
Toxicology and Applied Pharmacology
, vol.207
-
-
Snow, E.T.1
Sykora, P.2
Durham, T.R.3
Klein, C.B.4
-
63
-
-
0347660925
-
Arsenic stimulates angiogenesis and tumorigenesis in vivo
-
Soucy NV, Ihnat MA, Kamat CD, Hess L, Post MJ, Klei LR, Clark C, and Barchowsky A. 2003. Arsenic stimulates angiogenesis and tumorigenesis in vivo. Toxicological Sciences 76:271-279.
-
(2003)
Toxicological Sciences
, vol.76
, pp. 271-279
-
-
Soucy, N.V.1
Ihnat, M.A.2
Kamat, C.D.3
Hess, L.4
Post, M.J.5
Klei, L.R.6
Clark, C.7
Barchowsky, A.8
-
64
-
-
33646501518
-
The dose makes the medicine
-
Stumpf WE. 2006. The dose makes the medicine. Drug Discoy Today 11(11-12):550-555.
-
(2006)
Drug Discoy Today
, vol.11
, Issue.11-12
, pp. 550-555
-
-
Stumpf, W.E.1
-
65
-
-
33646178390
-
Cost- opportunity analysis in clinical oncology: From the "wild far-west" to a correct integration of the disciplines, avoiding the "war of the worlds
-
Tassinari D, Poggi B, Fantini M, Tamburini E, Nicoletti S and Sartori S. 2006. Cost- opportunity analysis in clinical oncology: from the "wild far-west" to a correct integration of the disciplines, avoiding the "war of the worlds" letters to the editor 17(5):876-877.
-
(2006)
Letters to the Editor
, vol.17
, Issue.5
, pp. 876-877
-
-
Tassinari, D.1
Poggi, B.2
Fantini, M.3
Tamburini, E.4
Nicoletti, S.5
Sartori, S.6
-
66
-
-
27244440565
-
Fundamental flaws of hormesis for public health decisions
-
Thayer KA, Melnick R, Burns K, Davis D, and Huff J. 2005. Fundamental flaws of hormesis for public health decisions. Environ Health Perspect 113:1271-1276.
-
(2005)
Environ Health Perspect
, vol.113
, pp. 1271-1276
-
-
Thayer, K.A.1
Melnick, R.2
Burns, K.3
Davis, D.4
Huff, J.5
-
67
-
-
33745953353
-
Effects of low doses and high homeopathic potencies in normal and cancerous human lymphocytes: An in vitro isopathic study
-
Walchli D, Baumgartner S, and Bastide M. 2006. Effects of low doses and high homeopathic potencies in normal and cancerous human lymphocytes: An in vitro isopathic study. The Journal of Alternative and Complementary Medicine 12(5):421-427.
-
(2006)
The Journal of Alternative and Complementary Medicine
, vol.12
, Issue.5
, pp. 421-427
-
-
Walchli, D.1
Baumgartner, S.2
Bastide, M.3
-
68
-
-
85184359663
-
-
WHO, accessed on June 17, 2008
-
WHO 2008. http://www.who.int/dietphysicalactivity/publications/facts/ chronic/en/ (accessed on June 17, 2008)
-
(2008)
-
-
-
69
-
-
25144488561
-
Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy
-
Yap R, Veliceasa D, Emmenegger U, Kerbel RS, McKay LM, Henkin J, Volpert OV. 2005. Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy. Clin Cancer Res 11(18):6678-6685.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.18
, pp. 6678-6685
-
-
Yap, R.1
Veliceasa, D.2
Emmenegger, U.3
Kerbel, R.S.4
McKay, L.M.5
Henkin, J.6
Volpert, O.V.7
-
70
-
-
33744799963
-
Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors
-
Young SD, Whissell M, Noble JCS, Cano PO, Lopez PG, Germond CJ. 2006. Phase II clinical trial results involving treatment with low-dose daily oral cyclophosphamide, weekly vinblastine, and rofecoxib in patients with advanced solid tumors. Clin Cancer Res 12(10):3090-3098.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.10
, pp. 3090-3098
-
-
Young, S.D.1
Whissell, M.2
Noble, J.C.S.3
Cano, P.O.4
Lopez, P.G.5
Germond, C.J.6
-
71
-
-
15244342776
-
Paradoxical strategy for treating chronic diseases where the therapeutic effect is derived from compensatory response rather than drug effect
-
Yun AJ, Lee PY, Bazar KA. 2005. Paradoxical strategy for treating chronic diseases where the therapeutic effect is derived from compensatory response rather than drug effect. Medical Hypotheses 64:1050-1059.
-
(2005)
Medical Hypotheses
, vol.64
, pp. 1050-1059
-
-
Yun, A.J.1
Lee, P.Y.2
Bazar, K.A.3
|