Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Gα Proteins and its downstream PKA and PLC-β modulators by IGF-II

Chinese Journal of Physiology

Volumn 52, Issue 1, 2009, Pages 31-37

  Chu, Chun Hsien ^a   Huang, Chih Yang ^b,c   Lu, Ming Chin ^b   Lin, James A ^b   Tsai, Fuu Jen ^b   Tsai, Chang Hai ^c   Chu, Chia Yih ^a   Kuo, Wu Hsien ^d   Chen, Li Mien ^d   Chen, Ling Yun ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c ASIA UNIVERSITY   (Taiwan)

^d TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

Apoptosis; G ; IGF II; IGF2R

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; CASPASE 3; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C BETA; PROTEIN KINASE B; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN C RECEPTOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; IMMUNOPRECIPITATION; MYOBLAST; NICK END LABELING; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS; HEART DISEASES; HUMANS; INSULIN-LIKE GROWTH FACTOR II; MYOBLASTS, CARDIAC; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, IGF TYPE 1; RECEPTOR, IGF TYPE 2; SIGNAL TRANSDUCTION; TYRPHOSTINS;

EID: 70349546275     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: 10.4077/CJP.2009.AMH004     Document Type: Article

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