Determination of zearalenone by liquid chromatography/tandem mass spectrometry and application to a pharmacokinetic study

Biomedical Chromatography

Volumn 23, Issue 9, 2009, Pages 1014-1021

  Shin, Beom Soo ^a   Hong, Seok Hyun ^b   Hwang, Sang Wook ^b   Kim, Hyoung Jun ^b   Lee, Jong Bong ^b   Yoon, Hae Seong ^c   Kim, Do Jung ^c   Yoo, Sun Dong ^b  

^a Catholic University of Daegu   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c National Institute of Toxicological Research   (South Korea)

Author keywords

Liquid chromatography; Mass spectrometry; Stability; Zearalenone

Indexed keywords

BODY FLUIDS; FUNGI; HIGH PRESSURE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; RATS;

ANIMAL FEED; ASSAY METHODS; FUSARIUM; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; PHARMACOKINETIC STUDIES; RAT SERUM; ZEARALENONE;

MASS SPECTROMETRY;

ZEARALENONE;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; ELUTION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; QUALITY CONTROL; RAT; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANIMALIA; FUNGI; FUSARIUM; RATTUS;

EID: 70349512951     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1217     Document Type: Article

References (26)

1. Bennett JW and Klich M. Mycotoxins. Clinical Microbiology Reviews 2003; 16: 497.
2. Blokland MH, Sterk SS, Stephany RW, Launay EM, Kennedy DG and van Ginkel LA. Determination of resorcylic acid lactones in biological samples by GC-MS. Discrimination between illegal use and contamination with fusarium toxins. Analytical and Bioanalytical Chemistry 2006; 384: 1221.
3. Buhrman DL, Price PI and Rudewicz PJ. Quantitation of SR 27417 in human plasma using electrospray liquid chromatography-tandem mass spectrometry: a study of ion suppression. Journal of the American Society for Mass Spectrometry 1996; 7: 1099.
4. Dänicke S, Swiech E, Buraczewska L and Ueberschär KH. Kinetics and metabolism of zearalenone in young female pigs. Journal of Animal Physiology and Animal Nutrition 2005; 89: 268.
5. D'Mello JPF, Duffus CM and Duffus JH. Toxic Substances in Crop Plants. The Royal Society of Chemistry: Cambridge, 1991; 226.
6. Döll S, Dänicke S and Schnurrbusch U. The effect of increasing concentrations of Fusarium toxins in the diets for piglets on histological parameters of the uterus. Mycotoxin Research 2003; 19: 73.
7. Gimeno A. Rapid thin layer chromatographic determination of zearalenone in corn, sorghum, and wheat. Journal of the Association of Official Agricultural Chemists 1983; 66: 565.
8. Jodlbauer J, Zöllner P and Lindner W. Determination of zeranol, taleranol, zearalenone, α- and β-zearalenol in urine and tissue by high-performance liquid chromatography-tandem mass spectrometry. Chromatographia 2000; 51: 681.
9. Kuiper-Goodman T, Scott PM and Watanabe H. Risk assessment of the mycotoxin zearalenone. Regulatory Toxicology and Pharmacology 1987; 7: 253.
10. Launay FM, Young PB, Sterk SS, Blokland MH and Kennedy DG. Confirmatory assay for zeranol, taleranol and the Fusarium spp. toxins in bovine urine using liquid chromatography-tandem mass spectrometry. Food Additives and Contaminants 2004; 21: 52.
11. Mallis LM, Sarkahian AB, Harris HA, Zhang MY and McConnell OJ. Determination of rat oral bioavailability of soy-derived phytoestrogens using an automated on-column extraction procedure and electrospray tandem mass spectrometry. Journal of Chromatography B 2003; 796: 71.
12. Matuszewski BK, Constanzer ML and Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Analytical Chemistry 2003; 75: 3019.
13. Minervini F, Giannoccaro A, Cavallini A and Visconti A. Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters. Toxicology Letters 2005; 159: 272.
14. Nuryono N, Noviandi CT, Böhm J and Razzazi-Fazeli E. A limited survey of zearalenone in Indonesian maize-based food and feed by ELISA and high performance liquid chromatography. Food Control 2005; 16: 65.
15. Olsen ME, Pettersson HI, Sandholm KA and Kiessling KC. Quantitative liquid chromatographic method using fluorescence detection for determining zearalenone and its metabolites in blood plasma and urine. Journal of the Association of Official Agricultural Chemists 1985; 68: 632.
16. Prelusky DB, Warner RM and Trenholm HL. Sensitive analysis of the mycotoxin zearalenone and its metabolites in biological fluids by high-performance liquid chromatography. Journal of Chromatography 1989; 494: 267.
17. Schmidt K, Stachel C and Gowik P. Development and in-house validation of an LC-MS/MS method for the determination of stilbens and resorcyclic acid lactones in bovine urine. Analytical and Bioanalytical Chemistry 2008; 391: 1199.
18. Songsermsakul P, Sontag G, Cichna-Markl M, Zentek J and Razzazi-Fazeli E. Determination of zearalenone and its metabolites in urine, plasma and faeces of horses by HPLC-APCI-MS. Journal of Chromatography B 2006; 843: 252.
19. Sørensen LK and Elbæk TH. Determination of mycotoxins in bovine milk by liquid chromatography tandem mass spectrometry. Journal of Chromatography B 2005; 820: 183.
20. Tanaka T, Yoneda A, Inoue S, Sugiura Y and Ueno Y. Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography - mass spectrometry. Journal of Chromatography A 2000; 882: 23.
21. Trenholm HL, Warner RM and Farnworth ER. High performance liquid chromatographic method using fluorescence detection for quantitative analysis of zearalenone and α-zearalenone in blood plasma. Journal of the Association of Official Agricultural Chemists 1981; 64: 302.
22. Turner GV, Phillips TD, Heidelbaugh ND and Russell LH. High pressure liquid chromatographic determination of zearalenone in chicken tissues. Journal of the Association of Official Agricultural Chemists 1983; 66: 102.
23. van Bennekom EO, Brouwer L, Laurant EHM, Hooijerink H and Nielen MWF. Confirmatory analysis method for zeranol, its metabolites and related mycotoxins in urine by liquid chromatography-negative ion electrospray tandem mass spectrometry. Analytica Chimica Acta 2002; 473: 151.
24. Warner R, Ram BP, Hart LP and Pestka JJ. Screening of zearalenone in corn by competitive direct enzyme-linked immunosorbent assay. Journal of Agricultural and Food Chemistry 1986; 34: 714.
25. Zinedine A, Soriano JM, Moltó JC and Maňes J. Review on the toxicity, occurrence, metabolism, detoxification, regulation and intake of zearalenone: an oestrogenic mycotoxin. Food and Chemical Toxicology 2007; 45: 1.
26. Zöllinger P, Jodlbauer J, Kleinova M, Kahlbacher H, Kuhn T, Hochsteiner W and Linder W. Concentration levels of zearalenone and its metabolites in urine, muscle tissue, and liver samples of pigs fed with mycotoxin-contaminated oats. Journal of Agricultural and Food Chemistry 2002; 50: 2494.