Light chain-deficient mice produce novel multimeric heavy-chain-only IgA by faulty class switching

International Immunology

Volumn 21, Issue 8, 2009, Pages 957-966

  Matheson, Louise S ^a   Osborn, Michael J ^a   Smith, Jennifer A ^a   Corcos, Daniel ^a   Hamon, Maureen ^a   Chaouaf, Rima ^a   Coadwell, John ^a   Morgan, Geoff ^a   Oxley, David ^a   Brüggemann, Marianne ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

B cell receptor; Class switch recombination; Heavy chain disease; Heavy chain only antibodies; Lymphocyte development

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN J CHAIN;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; C57BL 6 MOUSE; CELL DIFFERENTIATION; CELL MATURATION; CELL TRANSPORT; CONTROLLED STUDY; COVALENT BOND; DNA DETERMINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; FECES; GENE AMPLIFICATION; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; HEAVY CHAIN DISEASE; IMMUNOGLOBULIN A DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOGLOBULIN LIGHT CHAIN GENE; MASS SPECTROMETRY; MILK; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVA; SPLEEN CELL; URINE;

ANIMALS; B-LYMPHOCYTES; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; MICE; MICE, KNOCKOUT; MILK; SALIVA; SPLEEN;

EID: 70349481762     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxp062     Document Type: Article

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