Abnormality of serum lipids are independently associated with increased serum calcium level in the adult Newfoundland population

Clinical Medicine: Endocrinology and Diabetes

Volumn 2009, Issue 2, 2009, Pages 15-23

  Kennedy, Aaron ^a   Vasdev, Sudesh ^a   Randell, Edward ^a   Xie, Ya Gang ^a   Green, Kristian ^a   Zhang, Hongwei ^a   Sun, Guang ^a,b  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b The General Hospital ^*  (Canada)

Author keywords

Confounding factors; Dyslipidemia,; Newfoundland population; Serum Ca++

Indexed keywords

CALCIUM; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PARATHYROID HORMONE; TRIACYLGLYCEROL; VITAMIN D; 25 HYDROXYVITAMIN D; ALBUMIN; LIPID;

ADULT; AGE; AGE DISTRIBUTION; ARTICLE; BODY COMPOSITION; CALCIUM BLOOD LEVEL; CANADA; CHOLESTEROL BLOOD LEVEL; CONFOUNDING VARIABLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; DRUG USE; DYSLIPIDEMIA; FEMALE; GENE INTERACTION; GENETIC VARIABILITY; HUMAN; HYPERCALCEMIA; LIFESTYLE; LIPID BLOOD LEVEL; MALE; NUTRITIONAL ASSESSMENT; OBESITY; PHYSICAL ACTIVITY; POPULATION RESEARCH; POSTMENOPAUSE; PREMENOPAUSE; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL; AGED; DRUG MONITORING; MENOPAUSE; PARATHYROID HORMONE BLOOD LEVEL; SEX RATIO;

EID: 70349480809     PISSN: None     EISSN: 11781173     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science. 1986;232:34-47.
2. Garcia CK, Wilund K, Arca M, et al. Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. Science. 2001;292:1394-8. Epub 2001 Apr 26.
3. Hegele R. Monogenic dyslipidemias: Window on determinants of plasma lipoprotein metabolism. Am J Hum Genet. 2001;69:1161-77.
4. Hu D, Hannah J, Gray RS, et al. Effects of obesity and body fat distribution on lipids and lipoproteins in nondiabetic American Indians: The Strong Heart Study. Obes Res. 2000;8:411-21.
5. Rexrode KM, Buring JE, Manson JE. Abdominal and total adiposity and risk of coronary heart disease in men. Int J Obes Relat Metab Disord. 2001;25:1047-56.
6. Ettinger WH, Wahl PW, Kuller LH, et al. Lipoprotein lipids in older people. Results from the Cardiovascular Health Study. The CHS Collaborative Research Group. Circulation. 1992;86:858-69.
7. Burchfiel CM, Abbott RD, Sharp DS, Curb JD, Rodriguez BL, Yano K. Distribution and correlates of lipids and lipoproteins in elderly Japanese- American men. The Honolulu Heart Program. Arterioscler Thromb Vasc Biol. 1996;16:1356-64.
8. Wilson P, D'Agostino R, Levy D, Belanger A, Silbershatz H, Kannel W. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97:1837-47.
9. Rodriguez C, Pablos-Méndez A, Palmas W, Lantigua R, Mayeux R, Berglund L. Comparison of modifiable determinants of lipids and lipoprotein levels among African-Americans, Hispanics, and Non-Hispanic Caucasians > or = 65 years of age living in New York City. Am J Cardiol. 2002;89:178-83. Diabetes. 1995;44:369-74.
10. Stern MP. Diabetes and cardiovascular disease: the "common soil" hypothesis.
11. DeFronzo RA, Ferrannini E. Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 1991;14:173-94.
12. McLaughlin T, Reaven G. Insulin resistance and hypertension. Patients in double jeopardy for cardiovascular disease. Geriatrics. 2000;55:28-32, 35.
13. Reaven GM. Multiple CHD risk factors in type 2 diabetes: beyond hyperglycaemia. Diabetes Obes Metab. 2002;4 Suppl 1:S13-8. Review.
14. Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation. 2007;116:39-48. Epub 2007 Jun 18.
15. Lind L, Jakobsson S, Lithell H, Wengle B, Ljunghall S. Relation of serum calcium concentration to metabolic risk factors for cardiovascular disease. BMJ. 1988;297(6654):960-3.
16. Berridge MJ, Lipp P, Bootman MD. The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol. 2000;1:11-21.
17. Resnick LM: Hypertension and abnormal glucose homeostasis: possible role of divalent ion metabolism. Am J Med. 1989;87:17S-22.
18. Stern MP. Do non-insulin-dependent diabetes mellitus and cardiovascular disease share common antecedents? Ann Intern Med. 1996;124:110-6.
19. Vanhala MJ, Kumpusalo EA, Pitkajarvi TK, Notkola IL, Takala JK: Hyperinsulinemia and clustering of cardiovascular risk factors in middle-aged hypertensive Finnish men and women. J Hypertens. 1997;15:475-81.
20. Fernandez-Real JM, Ricart W: Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev. 2003;24:278-301.
21. Sun G, Vasdev S, Martin G, Gadag V, Zhang HW. Altered calcium homeostasis is correlated with abnormalities of fasting serum glucose, insulin resistance and β-cell function in the Newfoundland population. Diabetes. 2005;54:3336-9.
22. Hagström E, Hellman P, Lundgren E, Lind L, Arnlöv J. Serum calcium is independently associated with insulin sensitivity measured with euglycaemic-hyperinsulinaemic clamp in a community-based cohort. Diabetologia. 2007;50:317-24. Epub 2006 Dec 20.
23. Wilson PW, Garrison RJ, Abbott RD, Castelli WP. Factors associated with lipoprotein cholesterol levels: The Framingham study. Arteriosclerosis. 1983;3:273-81.
24. Rychewaert A, Richet G, Lemaire V, Begue MC, Fenelon JP. Serum calcium levels in a population of 6048 men; variations with age and correlation with other biological data. Rev Rhum Mal Osteoartic. 1974; 41:473-8.
25. Kennedy A, Shea J, Sun G. Comparison of the classification of obesity by BMI versus dual-energy x-ray absorptiometry in the Newfoundland population. Obesity. 2009 Apr 9. [Epub ahead of print].
26. Randell E, Mathews M, Gadag V, Sun G. Relationship between serum magnesium values, lipids and anthropometric risk factors. Atherosclerosis. 2008;196(1):413-9.
27. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and betacell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-9.
28. Sun G, French C, Martin G, et al. Comparison of multifrequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of percentage body fat in a large, healthy population. Am J Clin Nutr. 2005;81:74-8.
29. Altura BM, Altura BT. Magnesium and cardiovascular biology: an important link between cardiovascular risk factors and atherogenesis. Cell Mol Biol Res. 1995;41:347-59.
30. Chakraborti S, Chakraborti T, Mandal M, et al. Protective role of magnesium in cardiovascular diseases: a review. Mol Cell Biochem. 2002; 238:163-79.
31. Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, Liu S. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005;28:1438-44.
32. Olatunji LA, Soladoye AO. Increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats. Pathophysiology. 2007;14:11-5. Epub 2006 Dec 21.
33. Pietiläinen KH, Sysi-Aho M, Rissanen A, et al. Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects - a monozygotic twin study. PLoS ONE. 2007;2(2):e218.
34. Schubert CM, Rogers NL, Remsberg KE, et al. Lipids, lipoproteins, lifestyle, adiposity and fat-free mass during middle age: the Fels Longitudinal Study. Int J Obes (Lond). 2006;30:251-60.
35. Erem C, Hacihasanoglu A, Deger O, Kocak M, Topbas M. Prevalence of dyslipidemia and associated risk factors among Turkish adults: Trabzon lipid study. Endocrine. 2008;34:36-51. Epub 2008 Nov 12.
36. McPherson R, Frohlich J, Fodor G, Genest J. Canadian Cardiovascular Society position statement- Recommendations for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease. Can J Cardiol. 2006;22:913-27.
37. Hildrum B, Mykletun A, Hole T, Midthjell K, Dahl AA. Age-specific prevalence of the metabolic syndrome defined by the International Diabetes Federation and the National Cholesterol Education Program: the Norwegian HUNT 2 study. BMC Public Health. 2007;7:220.
38. Feng Y, Hong X, Li Z, et al. Prevalence of metabolic syndrome and its relation to body composition in a Chinese rural population. Obesity. 2006;14:2089-98.
39. Clodfelter KH, Holloway MG, Hodor P, Park SH, Ray WJ, Waxman DJ. Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol Endocrinol. 2006;20:1333-51.
40. Ellegren H, Parsch J. The evolution of sex-biased genes and sex-biased gene expression. Nat Rev Genet. 2007;8:689-98.
41. Welle S, Tawil R, Thornton CA. Sex-related differences in gene expression in human skeletal muscle. PLoS ONE. 2008;3:e1385.
42. Stevenson JC, Crook D, Godsland IF. Influence of age and menopause on serum lipids and lipoproteins in healthy women. Atherosclerosis. 1993; 98:83-90.
43. De Bacquer D, De Henauw S, De Backer G, Kornitzer M. Epidemiological evidence for an association between serum calcium and serum lipids. Atherosclerosis. 1994;108:193-200.
44. Sullivan PW, Ghushchyan VH, Ben-Joseph R. The impact of obesity on diabetes, hyperlipidemia and hypertension in the United States. Qual Life Res. 2008;17:1063-71.
45. Grundy S. Metabolic Syndrome Pandemic. Arterioscler Thromb Vasc Biol. 2008;28;629-36.
46. Ford ES, Kohl HW, Mokdad AH, Ajani UA. Sedentary behavior, physical activity, and the metabolic syndrome among U.S. adults. Obes Res. 2005;13:608-14.
47. Vatanparast H, Chilibeck PD, Cornish SM, et al. DXA-derived abdominal fat mass, waist Circumference, and blood lipids in postmenopausal women. Obesity (Silver Spring). 2009 Apr 2. [Epub ahead of print].
48. Churilla J, Zoeller R. Physical Activity: Physical Activity and the Metabolic Syndrome: A Review of the Evidence. Am J Lifestyle Medicine. 2008;2:118-25.
49. Bullano MF, Wertz DA, Yang GW, et al. Effect of rosuvastatin compared with other statins on lipid levels and National Cholesterol Education Program goal attainment for low-density lipoprotein cholesterol in a usual care setting. Pharmacotherapy. 2006;26:469-78.
50. Elisaf M. Effects of fibrates on serum metabolic parameters. Curr Med Res Opin. 2002;18:269-76.
51. Stone NJ. Secondary causes of hyperlipidemia. Med Clin North Am. 1994; 78:117-41.
52. Bieglmayer C, Prager G, Niederle B. Kinetic analyses of parathyroid hormone clearance as measured by three rapid immunoassays during parathyroidectomy. Clin Chem. 2002;48:1731-8.