An engineered zinc finger protein reveals a role for the insulin VNTR in the regulation of the insulin and adjacent IGF2 genes

FEBS Letters

Volumn 583, Issue 19, 2009, Pages 3181-3186

  Ferguson, Laura A ^a   Docherty, Hilary M ^a   MacKenzie, Amanda E ^a   Docherty, Kevin ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Chromatin; Diabetes mellitus; Islets of Langerhans; Pancreatic cell; Pdx1; ZFP

Indexed keywords

INSULIN; SOMATOMEDIN; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CHROMOSOME 11P; CONTROLLED STUDY; GENE ACTIVATION; GENETIC REGULATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN FUNCTION; RAT; TRANSCRIPTION INITIATION SITE; VARIABLE NUMBER OF TANDEM REPEAT;

CELL LINE; EPIGENESIS, GENETIC; GENE EXPRESSION; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR II; MINISATELLITE REPEATS; PROTEIN ENGINEERING; PROTEINS; TRANSCRIPTION INITIATION SITE; ZINC FINGERS;

EID: 70349462799     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.08.041     Document Type: Article

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