Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression

Molecular Human Reproduction

Volumn 15, Issue 10, 2009, Pages 693-701

  Shimizu, Yutaka ^a   Takeuchi, Takashi ^a   Mita, Shizuka ^a   Mizuguchi, Kiyoshi ^a   Kiyono, Tohru ^b   Inoue, Masaki ^c   Kyo, Satoru ^c  

^a MOCHIDA PHARMACEUTICAL CO   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

Cell proliferation; Cyclin D1; Dienogest; Endometrial epithelial cells; Progesterone

Indexed keywords

BROXURIDINE; CYCLIN D1; CYCLIN E; CYCLIN E1; DIENOGEST; MESSENGER RNA; PROGESTERONE; PROTEIN P21; PROTEIN P27; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE REGULATION; CELL IMMORTALIZATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ENDOMETRIUM CELL; FEMALE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CYCLIN D1; CYCLIN E; ENDOMETRIUM; FEMALE; GENE EXPRESSION REGULATION; HORMONE ANTAGONISTS; HUMANS; IMMUNOHISTOCHEMISTRY; NANDROLONE; ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 70349423534     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gap042     Document Type: Article

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