Successful prevention of ventilator-associated pneumonia in an intensive care setting

American Journal of Infection Control

Volumn 37, Issue 8, 2009, Pages 619-625

  Marra, Alexandre R ^a   Cal, Ruy Guilherme Rodrigues ^a   Silva, Cláudia Vallone ^a   Caserta, Raquel Afonso ^a   Paes, Ângela Tavares ^a   Moura Jr , Denis Faria ^a   Pavão dos Santos, Oscar Fernando ^a,b   Edmond, Michael B ^c   Durão, Marcelino Souza ^a,b  

^a HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

critical care prevention; health care associated infection; infection control; Ventilator associated pneumonia; ventilator bundle

Indexed keywords

CHLORHEXIDINE;

ACINETOBACTER BAUMANNII; ARTICLE; DISEASE CONTROL; EVIDENCE BASED PRACTICE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEALTH CARE; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE; MICROBIOLOGY; MORTALITY; PATHOGENESIS; PREVALENCE; PSEUDOMONAS AERUGINOSA; QUASI EXPERIMENTAL STUDY; SECRETION; STAPHYLOCOCCUS; TIME; VENTILATOR ASSOCIATED PNEUMONIA; VOCAL CORD; WASTE MANAGEMENT;

BRAZIL; CRITICAL PATHWAYS; CROSS INFECTION; GUIDELINE ADHERENCE; HUMANS; INCIDENCE; INFECTION CONTROL; INTENSIVE CARE; INTENSIVE CARE UNITS; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDIES;

EID: 70349402064     PISSN: 01966553     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajic.2009.03.009     Document Type: Article

References (22)

1. Richard M.J., Edwards J.R., Culver D.H., and Gaynes R.P. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol 21 (2000) 510-515
2. Garrouste Orgeas M., Timsit J.F., Soufir L., Tafflet M., Adrie C., Philippart F., et al. Impact of adverse events on outcomes in intensive care unit patients. Crit Care Med 36 (2008) 2041-2047
3. Warren D.K., Shukla S.J., Olsen M.A., Kollef M.H., Hollenbeak C.S., Cox M.J., et al. Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med 31 (2003) 1312-1317
4. Centers for Disease Control and Prevention. Guidelines for preventing healthcare-associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC). MMWR Morb Mortal Wkly Rep 2004;53:1-36.
5. Uçkay I., Ahmed Q.A., Sax H., and Pittet D. Ventilator-associated pneumonia as a quality indicator for patient safety?. Clin Infect Dis 46 (2008) 557-563
6. Apisarnthanarak A., Pinitchai U., Thongphubeth K., Yuekyen C., Warren D.K., Zack J.E., et al. Effectiveness of an educational program to reduce ventilator-associated pneumonia in a tertiary care center in Thailand: a 4-year study. Clin Infect Dis 45 (2007) 704-711
7. Youngquist P., Carroll M., Farber M., Macy D., Madrid P., Ronning J., et al. Implementing a ventilator bundle in a community hospital. Jt Comm J Qual Patient Saf 33 (2007) 219-225
8. Babcock H.M., Zack J.E., Garrison T., Trovillion E., Jones M., Fraser V.J., et al. An educational intervention to reduce ventilator-associated pneumonia in an integrated health system: a comparison of effects. Chest 125 (2004) 2224-2231
9. Dodek P., Keenan S., Cook D., Heyland D., Jacka M., Hand L., et al. the Canadian Critical Care Trials Group; Canadian Critical Care Society. Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia. Ann Intern Med 141 (2004) 305-313
10. Garner J.S., Jarvis W.R., Emori T.B., Horan T.C., and Hughes J.M. CDC definitions for nosocomial infections. Am J Infect Control 6 (1988) 128-140
11. Wagner A.K., Soumerai S.B., Zhang F., and Ross-Degnan D. Segmented regression analysis of interrupted time series studies in medication use research. J Clin Pharm Ther 27 (2002) 299-309
12. Edmond M.B. Getting to zero: is it safe?. Infect Control Hosp Epidemiol 30 (2009) 74-76
13. Coffin S.E., Klompas M., Classen D., Arias K.M., Podgorny K., Anderson D.J., et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect Control Hosp Epidemiol 29 (2008) S31-S40
14. Assanasen S., Edmond M.B., and Bearman G. Impact of 2 different levels of performance feedback on compliance with infection control process measures in 2 intensive care units. Am J Infect Control 36 (2008) 407-413
15. Bouza E., Jesús Pérez M., Muñoz P., Rincón C., Barrio J.M., and Hortal J. Continuous aspiration of subglottic secretions (CASS) in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery. Chest 134 (2008) 938-946
16. Vallés J., Artigas A., Rello J., Bonsoms N., Fontanals D., Blanch L., et al. Continuous aspiration of subglottic secretions in preventing ventilator-associated pneumonia. Ann Intern Med 122 (1995) 179-186
17. Kollef M.H., Skubas N.J., and Sundt T.M. A randomized clinical trial of continuous aspiration of subglottic secretions in cardiac surgery patients. Chest 116 (1999) 1339-1346
18. Tantipong H., Morkchareonpong C., Jaiyindee S., and Thamlikitkul V. Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia. Infect Control Hosp Epidemiol 29 (2008) 131-136
19. Chlebicki M.P., and Safdar N. Topical chlorhexidine for prevention of ventilator-associated pneumonia: a meta-analysis. Crit Care Med 35 (2007) 595-602
20. Koeman M., van der Ven A.J., Hak E., Joore J.C., Kaasjager H.A., de Smet A.M., et al. Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med 173 (2006) 1348-1355
21. Klompas M., and Platt R. Ventilator-associated pneumonia: the wrong quality measure for benchmarking. Ann Intern Med 147 (2007) 803-805
22. Klompas M., Kulldorff M., and Platt R. Risk of misleading ventilator-associated pneumonia rates with use of standard clinical and microbiological criteria. Clin Infect Dis 46 (2008) 1443-1446