Chemical aspects of pharmacological prophylaxis against nerve agent poisoning

Current Medicinal Chemistry

Volumn 16, Issue 23, 2009, Pages 2977-2986

  Bajgar, Jiri ^a   Fusek, Josef ^a   Kassa, Jiri ^a   Kuca, Kamil ^a,b,c   Jun, Daniel ^a,b  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c J E PURKINJE UNIVERSITY   (Czech Republic)

Author keywords

Nerve agents; Other proteins; Present antidotes; Principles; Prophylactics; Scavengers; Simple drugs

Indexed keywords

ACETYLCHOLINESTERASE; ANTICONVULSIVE AGENT; ANTIDOTE; ATROPINE; BENACTYZINE; BIPERIDEN; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CHOLINESTERASE REACTIVATOR; HUPERZINE A; MEMANTINE; MEPTAZINOL; NIMODIPINE; ORGANOPHOSPHATE; PHOSPHOTRIESTERASE; PHYSOSTIGMINE; PRALIDOXIME; PROCYCLIDINE; PYRIDOSTIGMINE; SCOPOLAMINE; TRIHEXYPHENIDYL; TUBOCURARINE CHLORIDE;

BINDING SITE; COGNITIVE DEFECT; COMBINATION CHEMOTHERAPY; DETOXIFICATION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG MEGADOSE; DRUG POTENCY; DRUG POTENTIATION; DRUG SAFETY; DRUG STRUCTURE; HUMAN; INTOXICATION; MAXIMUM PLASMA CONCENTRATION; MONOTHERAPY; NONHUMAN; PROPHYLAXIS; RECOMMENDED DRUG DOSE; REVIEW; TIME TO MAXIMUM PLASMA CONCENTRATION; TOXICOKINETICS; UNSPECIFIED SIDE EFFECT;

ACETYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINERGIC ANTAGONISTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; HUMANS; PHOSPHORIC ACID ESTERS; POISONING;

EID: 70349380002     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709788803088     Document Type: Review

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