The isolation and identification of a secreted biomarker associated with cell stress in serum-free CHO cell culture

Biotechnology and Bioengineering

Volumn 104, Issue 3, 2009, Pages 590-600

  Woolley, John F ^a   Al Rubeai, Mohamed ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cell culture; Cell stress; CHO; Monitoring; Proteomics; SELDI

Indexed keywords

CELL STRESS; CHO; CHO CELL; CULTURE MEDIA; GALECTIN-1; GROWTH PHASE; IN-CELL; ISOLATION AND IDENTIFICATION; MAMMALIAN CELL CULTURE; NUTRIENT DEPLETION; PEAK HEIGHT; PROTEIN COMPONENTS; PROTEOMICS; RELATIVE INTENSITY; SELDI; SIGNAL/NOISE RATIO; TOF MASS SPECTROMETRY; TOXIC METABOLITES;

AMINO ACIDS; ANIMAL CELL CULTURE; BIOMARKERS; CELL DEATH; CELL MEMBRANES; MAMMALS; MASS SPECTROMETRY; MOLECULAR BIOLOGY; PRODUCTIVITY; PROTEINS;

CELL CULTURE;

BIOLOGICAL MARKER; GALECTIN 1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRESS; CELL VIABILITY; CHO CELL; CULTURE MEDIUM; MAMMAL CELL; NONHUMAN; PROTEIN ISOLATION; PROTEIN SYNTHESIS; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA, SERUM-FREE; GALECTIN 1; MASS SPECTROMETRY; MOLECULAR WEIGHT; STRESS, PHYSIOLOGICAL;

MAMMALIA;

EID: 70349333750     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22408     Document Type: Article

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