Kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH

Biotechnology and Bioengineering

Volumn 67, Issue 6, 2000, Pages 853-871

  Miller, W M ^a,b   Blanch, H W ^a   Wilke, C R ^a  

^a University of California   (United States)

^b Northwestern University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BATCH CELL CULTURE; CELLS; CONCENTRATION (PROCESS); GLUCOSE; METABOLISM; MONOCLONAL ANTIBODIES; PH EFFECTS;

CONTINUOUS SUSPENSION CULTURE; DILUTION RATE; GLUTAMINE; HYBRIDOMA; NUTRIENT CONCENTRATION;

GROWTH KINETICS;

GLUCOSE; GLUTAMINE; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BIOSYNTHESIS; CULTURE MEDIUM; CYTOLOGY; HISTORY; HYBRIDOMA; KINETICS; METABOLISM; MOUSE; PH; PHYSIOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; CULTURE MEDIA; GLUCOSE; GLUTAMINE; HISTORY, 20TH CENTURY; HYBRIDOMAS; HYDROGEN-ION CONCENTRATION; KINETICS; MICE;

EID: 0034688709     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(20000320)67:6<853::AID-BIT20>3.0.CO;2-4     Document Type: Article

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