Cytolysins, superantigens, and pneumonia due to community-associated methicillin-resistant staphylococcus aureus

Journal of Infectious Diseases

Volumn 200, Issue 5, 2009, Pages 676-678

  Schlievert, Patrick M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOXIN; BIOLOGICAL MARKER; CYTOLYSIN; METICILLIN; PANTON VALENTINE LEUKOCIDIN; STAPHYLOCOCCUS ENTEROTOXIN B; STAPHYLOCOCCUS ENTEROTOXIN C; SUPERANTIGEN; TOXIC SHOCK SYNDROME TOXIN 1; VIRULENCE FACTOR; BACTERIAL PROTEIN; CYTOTOXIN;

BACTERIAL STRAIN; BACTERIAL VIRULENCE; COMMUNITY ACQUIRED PNEUMONIA; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN FUNCTION; COMMUNICABLE DISEASE; IMMUNOLOGY; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; STAPHYLOCOCCAL PNEUMONIA; UNITED STATES; VIRULENCE;

BACTERIAL PROTEINS; COMMUNITY-ACQUIRED INFECTIONS; CYTOTOXINS; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PNEUMONIA, STAPHYLOCOCCAL; SUPERANTIGENS; UNITED STATES; VIRULENCE; VIRULENCE FACTORS;

EID: 70349326554     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/605333     Document Type: Note

References (31)

1. Klevens RM, Morrison MA, Nadle J, et al. Invasive methicillin-resistant Staphylococcus aureus infections in the United States, JAMA 2007;298:1763-1771
2. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus- Minnesota and North Dakota, 1997-1999. JAMA 1999; 282:1123-1125
3. Methicillin-resistant Staphylococcus aureus infections in correctional facilities-Georgia, California, and Texas, 2001-2003, MMWR Morb Mortal Wkly Rep 2003;52:992-996
4. Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk, JAMA 1998; 279:593-598
5. Assimacopoulos AP, Strandberg KL, Rotschafer JH, Schlievert PM, Extreme pyrexia and rapid death due to Staphylococcus aureus infection: analysis of 2 cases, Clin Infect Dis 2009;48:612-614
6. Adem PV, Montgomery CP, Husain AN, et al. Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children, N Engl J Med 2005; 353:1245-1251
7. Kravitz G, Dries, DJ, Peterson, ML, Schlievert, PM, Purpura fulminans due to Staphylococcus aureus. Clin Infect Dis 2005;40:941-947,
8. MacDonald KL, Osterholm MT, Hedberg CW, et al. Toxic shock syndrome: a newly recognized complication of influenza and influenzalike illness. JAMA 1987;257:1053-1058
9. Hongo I, Baba T, Oishi K, Morimoto Y, Ito T, Hiramatsu K, Phenol-soluble modulin α3 enhances the human neutrophil lysis mediated by Panton-Valentine leukocidin, J Infect Dis 2009;200:715-723 (in this issue).
10. Dufour P, Gillet Y, Bes M, et al. Communityacquired methicillin-resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin Infect Dis 2002;35:819-824
11. Vandenesch F, Naimi T, Enright MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence, Emerg Infect Dis 2003; 9:978-984
12. Voyich JM, Otto M, Mathema B, et al. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis 2006; 194:1761-1770
13. Labandeira-Rey M, Couzon F, Boisset S, et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia, Science 2007;315:1130-1133
14. Bubeck Wardenburg J, Bae T, Otto M, Deleo FR, Schrieewind O, Poring over pores: alphahemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia, Nat Med 2007; 13:1405-1406
15. Bubeck Wardenburg J, Schrieewind O, Vaccine protection against Staphylococcus aureus pneumonia. J Exp Med 2008;205:287-294
16. 16. Wang R, Braughton KR, Kretschmer D, et al. Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med 2007; 13:1510-1514 (Pubitemid 350224240)
17. Kaneko J, Kamio Y. Bacterial two-component and hetero-heptameric pore-forming cytolytic toxins: structures, pore-forming mechanism, and organization of the genes, Biosci Biotechnol Biochem 2004;68:981-1003.
18. Gouaux JE, Braha O, Hobaugh MR, et al. Subunit stoichiometry of staphylococcal alpha-hemolysin in crystals and on membranes: a heptameric transmembrane porc, Proc Natl Acad Sci U S A 1994; 91:12828-12831
19. 19. Sriskandan S, Unnikrishnan M, Krausz T, Cohen J, Molecular analysis of the role of streptococcal pyrogenic Exotoxin A (SPEA) in invasive soft-tissue infection resulting from Streptococcus pyogenes. Mol Microbiol 1999; 33:778-790 (Pubitemid 29392658)
20. Unnikrishnan M, Cohen J, Sriskandan S. Complementation of a speA negative Streptococcus pyogenes with speA: effects on virulence and production of streptococcal pyrogenic exotoxin A. Microb Pathog 2001; 31: 109-114
21. Dinges MM, Jessurun J, Schlievert PM. Comparisons of mouse and rabbit models of toxic shock syndrome, International Congress and Symposium Series 1998;229:167-168
22. 22. McCormick JK, Yarwood JM, Schlievert PM, Toxic shock syndrome and bacterial superantigens: an update, Annu Rev Microbiol 2001;55:77-104. (Pubitemid 32978101)
23. Schlievert PM, Tripp TJ, Peterson ML. Reemergence of staphylococcal toxic shock syndrome in Minneapolis-St. Paul, Minnesota, during the 2000-2003 surveillance period. J Clin Microbiol 2004;42:2875-2876
24. Schlievert PM. Staphylococcal enterotoxin B and toxic-shock syndrome toxin-1 are significantly associated with non-menstrual TSS. Lancet 1986;1:1149-1150
25. 25. Giantonio BJ, Alpaugh RK, Schultz J, et al. Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody- staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer, J Clin Oncol 1997; 15: 1994-2007. (Pubitemid 27209530)
26. Diep BA, Gill SR, Chang RF, et al. Complete genome sequence of USA300, an epidemic clone of community-acquired methicillinresistant Staphylococcus aureus. Lancet 2006; 367:731-739
27. Orwin PM, Leung DY, Tripp TJ, et al. Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins, Biochemistry 2002; 41:14033-14040
28. Melish ME, Murata S, Fukunaga C, Frogner K, McKissick C. Vaginal tampon model for toxic shock syndrome, Rev Infect Dis 1989; 11(Suppl 1):S238-46.
29. Parsonnet J, Gillis ZA, Richter AG, Pier GB, A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1, Infect Immun 1987;55:1070-1076
30. Lee PK, Deringer JR, Kreiswirth BN, Novick RP, Schlievert PM, Fluid replacement protection of rabbits challenged subcutaneous with toxic shock syndrome toxins, Infect Immun 1991;59:879-884
31. Strandberg KL, Schlievert PM, Staphylococcal superantigens contribute to necrotizing pneumonia in rabbits [abstract B-055]. In: Program and abstracts of the 108th General Meeting of the American Society for Microbiology. 2008:41.