Polymorphisms in the promoter region of the interleukin-10 (IL-10) gene in women with cervical insufficiency

American Journal of Obstetrics and Gynecology

Volumn 201, Issue 4, 2009, Pages 372.e1-372.e5

  Warren, Jennifer E ^a   Nelson, Lesa M ^c   Stoddard, Gregory J ^b   Esplin, M Sean ^a   Varner, Michael W ^a   Silver, Robert M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^c Taueret Laboratories   (United States)

Author keywords

cervical insufficiency; IL 10; inflammation; polymorphisms

Indexed keywords

INTERLEUKIN 10; MICROSATELLITE DNA;

ALLELE; ARTICLE; BLOOD SAMPLING; CASE CONTROL STUDY; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; DNA EXTRACTION; DOWN REGULATION; FEMALE; GENE; GENETIC POLYMORPHISM; HUMAN; INFLAMMATION; INTERLEUKIN 10 GENE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; UTERINE CERVIX INCOMPETENCE;

EID: 70349318045     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2009.05.022     Document Type: Article

References (21)

1. Parisi V.N. Cervical incompetence and preterm labor. Clinical Obstet Gynecol 31 (1988) 585-598
2. Rechberger T., Uldbjerg N., and Oxlund H. Connective tissue changes during normal pregnancy and pregnancy complicated by cervical incompetence. Obstet Gynecol 71 (1988) 563-567
3. Iams J.D., Goldenberg R.L., Meis P.J., et al. The length of the cervix and the risk of spontaneous preterm delivery. N Engl J Med 334 (1996) 567-572
4. Berghella V., Odibo A.O., and Tolosa J.E. Cerclage for prevention of preterm birth in women with a short cervix found on transvaginal ultrasound examination: a randomized trial. Am J Obstet Gynecol 191 (2004) 1311-1317
5. Rust O.A., Atlas R.O., Reed J., van Gaalen J., and Balducci J. Revisiting the short cervix found by transvaginal ultrasound in the second trimester: why cerclage therapy may not help. Am J Obstet Gynecol 185 (2001) 1098-1105
6. Pretolani M., and Goldman M. IL-10: a potential therapy for allergic inflammation?. Immunology Today 18 (1997) 277-280
7. Eskdale J., and Gallagher G. A polymorphic dinucleotide repeat in the human IL-10 promoter. Immunogenetics 42 (1995) 444-445
8. Huizinga T.W.J., Keijsers V., Yanni G., et al. Are differences in interleukin 10 production associated with joint damage?. Rheumatology 39 (2000) 1180-1188
9. D'Alfonso S., Giordano M., Mellai M., et al. Association tests with systemic lupus erythematosus (SLE) of IL10 markers indicate a direct involvement of a CA repeat in the 5' regulatory region. Genes Immun 3 (2002) 454-463
10. Shu Q., Shi C.C., Zhang X.H., et al. Interleukin 10.G microsatellite in the promoter region of the interleukin-10 gene in severe sepsis. Chin Med J (Engl) 119 (2006) 197-201
11. Lewis C.M. Genetic association studies: design, analysis, and interpretation. Brief Bioinform 3 (2002) 146-153
12. Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc, Series B (Methodological) 57 (1995) 289-300
13. Warren J.E., Silver R.M., Dalton J., Nelson L.T., Branch D.W., and Porter T.F. Collagen 1A1 and transforming growth factor-β polymorphisms in women with cervical insufficiency. Obstet Gynecol 110 (2007) 619-624
14. Romero R., Espinoza J., Erez O., and Hassan S. The role of cervical cerclage in obstetric practice: can the patient who could benefit from this procedure be identified?. Am J Obstet Gynecol 194 (2006) 1-9
15. Lee K.Y., Jun H.A., Kim H.B., and Kang S.W. Interleukin-6, but not relaxin, predicts outcome of rescue cerclage in women with cervical incompetence. Am J Obstet Gynecol 191 (2004) 784-789
16. Weiner C.P., Lee K.Y., Buhimschi C.S., Christner R., and Buhimschi I.A. Proteomic biomarkers that predict the clinical success of rescue cerclage. Am J Obstet Gynecol 192 (2005) 710-718
17. Goldenberg R.L., Culhane J.F., Iams J.D., and Romero R. Epidemiology and causes of preterm birth. Lancet 371 (2008) 75-84
18. Park J.S., Park C.W., Lockwood C.J., and Norwitz E.R. Role of cytokines in preterm labor and birth. Minerva Ginecol 57 (2005) 349-366
19. Rees L.E., Wood N.A., Gillespie K.M., Lai K.N., Gaston K., and Mathieson P.W. The IL-10-1082 G/A polymorphism: allele frequencies in different populations and functional significance. Cell Mol Life Sci 59 (2002) 560-569
20. Rosner B. Fundamentals of biostatistics. 6th ed. (2006), Thomson Brooks/Cole, Belmont, CA
21. Moyé L.A. The multiple comparison issue in health care research. In: Rao C.R., Miller J.P., and Rao D.C. (Eds). Handbook of statistics 27: epidemiology and medical statistics (2008), Elsevier, New York 616-665