Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 35, 2009, Pages 14808-14813

  Spektor, Tanya M ^a   Rice, Judd C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

53BP1; G9a; Histone; JMJD2A; Methylation

Indexed keywords

HETEROCHROMATIN PROTEIN 1; HISTONE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METHYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN PURIFICATION;

ANIMALS; BIOCATALYSIS; BIOCHEMISTRY; CELL LINE; CERCOPITHECUS AETHIOPS; CHROMOSOMAL PROTEINS, NON-HISTONE; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; METHYLATION; OXIDOREDUCTASES, N-DEMETHYLATING; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 70349283086     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907799106     Document Type: Article

References (26)

1. Guo D, et al. (2004) A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications. Nat Biotechnol 22:888-892. (Pubitemid 38886610)
2. Jenuwein T, Allis CD (2001) Translating the histone code. Science 293:1074-1080.
3. Tachibana M, Sugimoto K, Fukushima T, Shinkai Y (2001) Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J Biol Chem 276:25309-25317. (Pubitemid 37413016)
4. Tachibana M, et al. (2002) G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 16:1779-1791. (Pubitemid 34803894)
5. Peters AH, et al. (2003) Partitioning and plasticity of repressive histone methylation States in Mammalian chromatin. Mol Cell 12:1577-1589.
6. Rice JC, et al. (2003) Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell 12:1591-1598.
7. Collins RE, et al. (2005) In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases. J Biol Chem 280:5563-5570.
8. Bannister AJ, et al. (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410:120-124. (Pubitemid 32225848)
9. Jacobs SA, Khorasanizadeh S (2002) Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail. Science 295:2080-2083. (Pubitemid 34229471)
10. Jacobs SA, et al. (2001) Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J 20:5232-5241. (Pubitemid 32910917)
11. Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120. (Pubitemid 32225847)
12. Peters AH, et al. (2002) Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin. Nat Genet 30:77-80. (Pubitemid 34886693)
13. Peters AH, et al. (2001) Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107:323-337.
14. Couture JF, Collazo E, Brunzelle JS, Trievel RC (2005) Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase. Genes Dev 19:1455-1465. (Pubitemid 41003012)
15. Schotta G, et al. (2004) A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18:1251-1262. (Pubitemid 38720593)
16. Xiao B, et al. (2005) Specificity and mechanism of the histone methyltransferase Pr-Set7. Genes Dev 19:1444-1454. (Pubitemid 41003011)
17. Kim J, et al. (2006) Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Rep 7:397-403.
18. Maurer-Stroh S, et al. (2003) The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends Biochem Sci 28:69-74. (Pubitemid 36165134)
19. Lee J, Thompson JR, Botuyan MV, Mer G (2008) Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat Struct Mol Biol 15:109-111.
20. Botuyan MV, et al. (2006) Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127:1361-1373.
21. Tachibana M, et al. (2005) Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev 19:815-826. (Pubitemid 40502984)
22. Collins RE, et al. (2008) The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules. Nat Struct Mol Biol 15:245-250.
23. Sampath SC, et al. (2007) Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell 27:596-608.
24. Sutherland BW, Toews J, Kast J (2008) Utility of formaldehyde cross-linking and mass spectrometry in the study of protein-protein interactions. J Mass Spectrom 43:699-715. (Pubitemid 351954805)
25. Trinkle-Mulcahy L, et al. (2008) Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol 183:223-239.
26. Sims JK, Houston SI, Magazinnik T, Rice JC (2006) A trans-tail histone code defined by monomethylated H4 Lys-20 and H3 Lys-9 demarcates distinct regions of silent chromatin. J Biol Chem 281:12760-12766. (Pubitemid 43855367)