Optimization of melt pelletization in a high shear mixer

International Journal of Pharmaceutics

Volumn 381, Issue 2, 2009, Pages 192-198

  Bukovec, P ^a   Kroselj V ^a   Turk, S ^a   Vrecer F ^a,b  

^a KRKA D D   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Gelucire 50 13; High shear mixer; Lansoprazole; Lutrol F68; Melt pelletization; Process parameters

Indexed keywords

GELUCIRE; LANSOPRAZOLE; POLOXAMER;

ANALYSIS OF VARIANCE; ARTICLE; CONCENTRATION PROCESS; DRUG PELLET; EXPERIMENTAL DESIGN; MELTING POINT; MIXER; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUALITATIVE ANALYSIS; VISCOSITY;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANALYSIS OF VARIANCE; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG COMPOUNDING; EXCIPIENTS; FATS; HOT TEMPERATURE; MAGNESIUM; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; OILS; PARTICLE SIZE; PHASE TRANSITION; POLYETHYLENE GLYCOLS; QUALITY CONTROL; RHEOLOGY; SOLUBILITY; SURFACE PROPERTIES; TABLETS; TIME FACTORS; TRANSITION TEMPERATURE; VISCOSITY;

EID: 70349269074     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.06.036     Document Type: Article

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