Screening of high shear mixer melt granulation process variables using an asymmetrical factorial design

International Journal of Pharmaceutics

Volumn 190, Issue 1, 1999, Pages 73-81

  Voinovich, D ^a   Campisi, B ^a   Moneghini, M ^a   Vincenzi, C ^a   Phan Tan Luu, R ^b  

^a UNIVERSITY OF TRIESTE   (Italy)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Asymmetrical factorial design; Factor level screening; High shear mixer; Melt granulation

Indexed keywords

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG GRANULATION; DRUG SYNTHESIS; METHODOLOGY; NONHUMAN; POWDER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; LACTOSE; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; MULTIVARIATE ANALYSIS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POWDERS; RESEARCH DESIGN;

EID: 0032850380     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00278-1     Document Type: Article

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