Detection of protein aggregates by sedimentation velocity analytical ultracentrifugation (SV-AUC): Sources of variability and their relative importance

Journal of Pharmaceutical Sciences

Volumn 98, Issue 10, 2009, Pages 3522-3539

  Arthur, Kelly K ^a   Gabrielson, John P ^a   Kendrick, Brent S ^a   Stoner, Michael R ^b  

^a AMGEN INC   (United States)

^b GENENCOR INTERNATIONAL INC   (United States)

Author keywords

Analytical ultracentrifugation; Protein aggregation; SEDFIT; Sedimentation velocity

Indexed keywords

MONOCLONAL ANTIBODY;

ARTICLE; GEL PERMEATION CHROMATOGRAPHY; KNEE MENISCUS; PROTEIN AGGREGATION; SEDIMENTATION RATE; SEPARATION TECHNIQUE; TEMPERATURE SENSITIVITY; ULTRACENTRIFUGATION;

EID: 70349260206     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21654     Document Type: Article

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