Preterm resuscitation with low oxygen causes less oxidative stress, inflammation, and chronic lung disease

Pediatrics

Volumn 124, Issue 3, 2009, Pages

  Vento, Maximo ^a   Moro, Manuel ^b   Escrig, Raquel ^a   Arruza, Luis ^b   Villar, Gema ^b   Izquierdo, Isabel ^a   Roberts II, L Jackson ^c   Arduini, Alessandro ^d   Escobar, Justo Javier ^d   Sastre, Juan ^d   Asensi, Miguel A ^d  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c VANDERBILT UNIVERSITY   (United States)

^d UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Bronchopulmonary dysplasia; Inflammatory cytokines; Oxidative stress biomarkers; Oxygen; Prematurity; Resuscitation

Indexed keywords

3 (2 HYDROXYPHENYL)ALANINE; 8 HYDROXYDEOXYGUANOSINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; ICOSANOID; INTERLEUKIN 8; ISOFURAN DERIVATIVE; ISOPROSTANE; ISOPROSTANE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CHRONIC LUNG DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; HEART RATE; HUMAN; INFLAMMATION; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN INTENSIVE CARE; OXIDATIVE STRESS; OXYGEN BREATHING; OXYGEN SATURATION; OXYGEN THERAPY; PREMATURITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; RESUSCITATION; RISK FACTOR; URINARY EXCRETION; URINE LEVEL;

BRONCHOPULMONARY DYSPLASIA; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFLAMMATION; MALE; OXIDATIVE STRESS; OXYGEN; OXYGEN INHALATION THERAPY; PROSPECTIVE STUDIES; RESUSCITATION;

EID: 70349252005     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2009-0434     Document Type: Article

References (54)

1. Markestad T, Kaaresen P, Ronnestad A. Early death, morbidity and need of treatment among extremely premature infants. Pediatrics. 2005;115(5):1289-1298 (Pubitemid 43843233)
2. Fanaroff AA, Stoll BJ, Wright LL, et al. Trends in neonatal morbidity and mortality for very low birth weight infants. Am J Obstet Gynecol. 2007;196(2):147.e1-147.e8
3. Branco de Almeida MF, Guinsburg R, Martinez FE, et al. Perinatal factors associated with early deaths of preterm infants born in Brazilian Network on Neonatal Research centers[in Portuguese]. J Pediatr (Rio J). 2008;84(4):300-307
4. Field DJ, Dorling JS, Manktelow BN, Draper ES. Survival of extremely premature babies in a geographically defined population: prospective cohort study of 1994 -9 compared with 2000 -5. BMJ. 2008;336(7655):1221-1223
5. Landmann E, Misselwitz B, Steiss JO, Gortner L. Mortality and morbidity of neonates born at <26 weeks gestation (1998 -2003): a population-based study. J Perinat Med. 2008;36(2):168-174
6. Baraldi E, Filippone M. Chronic lung disease after premature birth. N Engl J Med. 2007;357(19): 1946-1955 (Pubitemid 350074689)
7. Leone TA, Rich W, Finer NN. A survey of delivery room resuscitation practices in the United States. Pediatrics. 2006;117(2). Available at: www.pediatrics.org/cgi/content/full/117/2/e164 (Pubitemid 46071570)
8. Jobe AH, Hillman N, Polglase G, Kramer BW, Kallapur SH, Pillow J. Injury and inflammation from resuscitation of the preterm infant. Neonatology. 2008;94(3):190-196
9. Saugstad OD. Optimal oxygenation at birth and in the neonatal period. Neonatology. 2007;91(4): 319-322
10. Maltepe E, Saugstad OD. Oxygen in health and disease: regulation of oxygen homeostasis: clinical implications. Pediatr Res. 2009;65(3):261-268
11. Bhandari V. Molecular mechanisms of hyperoxia-induced acute lung injury. Front Biosci. 2008;13: 6653-6661
12. Buccellato LJ, Tso M, Akinci OI, Chandel NS, Budinger GRS. Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells. J Biol Chem. 2004; 279(8):6753-6760 (Pubitemid 38248816)
13. Saugstad OD, Ramji S, Soll RF, Vento M. Resuscitation of newborn infants with 21% or 100% oxygen: an updated systematic review and meta-analysis. Neonatology. 2008;94(3):174-182
14. Vento M, Asensi M, Sastre J, García-Sala F, Pallardó FV, Viña J. Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates. Pediatrics. 2001;107(4):642-647 (Pubitemid 32268445)
15. Vento M, Sastre J, Asensi MA, Viña J. Room-air resuscitation causes less damage to heart and kidney than 100% oxygen. Am J Respir Crit Care Med. 2005;172(11):1393-1398 (Pubitemid 43069812)
16. Saugstad OD, Ramji S, Irani SF, et al. Resuscitation of newborn infants with 21% or 100% oxygen: follow-up at 18 to 24 months. Pediatrics. 2003;112(2):296-300 (Pubitemid 36951389)
17. Vento M, Asensi M, Sastre J, et al. Hyperoxemia caused by resuscitation with pure oxygen may alter intracellular redox status by increasing oxidized glutathione in asphyxiated newly born infants. Semin Perinatol. 2002;26(6):406-410 (Pubitemid 36133538)
18. Vento M, Asensi M, Sastre J, Lloret A, García-Sala F, Viña J. Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen [published correction appears in J Pediatr. 2003;142(6): 616]. J Pediatr. 2003;142(3):240-246
19. Viña J, Vento M, García-Sala F, et al. L-Cysteine and glutathione metabolism are impaired in premature infants due to cystathionase deficiency. Am J Clin Nutr. 1995;61(5):1067-1069
20. Ledo A, Arduini A, Asensi MA, et al. Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants. Am J Clin Nutr. 2009;89(1):210-215
21. Asikainen TM, White CW. Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD? Toxicol Appl Pharmacol. 2005;203(2):177-188
22. Ballard PL, Truog WE, Merrill JD, et al. Plasma biomarkers of oxidative stress: relationship to lung disease and inhaled nitric oxide therapy in premature infants. Pediatrics. 2008;121(3):555-561
23. Harling AE, Beresford MW, Vince GS, Bates M, Yoxall CW. Does use of 50% oxygen at birth in preterm infants reduce lung injury? Arch Dis Child Fetal Neonatal Ed. 2005;90(5):F401-F405 (Pubitemid 41224075)
24. Wang CL, Anderson C, Leone TA, Rich W, Govindaswami B, Finer NN. Resuscitation of preterm neonates by using room air or 100% oxygen. Pediatrics. 2008;121(6):1083-1089
25. Dawson JA, Kamlin CO, Wong C, et al. Oxygen saturation and heart rate during delivery room resuscitation of infants <30 weeks' gestation with air or 100% oxygen. Arch Dis Child Fetal Neonatal Ed. 2009;94(2):F87-F91
26. Escrig R, Arruza L, Izquierdo I, et al. Achievement of targeted saturation values in extremely low gestational age neonates resuscitated with low or high oxygen concentrations: a prospective, randomized trial. Pediatrics. 2008;121(5):875-881
27. Solberg R, Andresen JH, Escrig R, Vento M, Saugstad OD. Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation. Pediatr Res. 2007;62(5): 559-563 (Pubitemid 351338990)
28. Davies SS, Zackert W, Luo Y, Cunningham CC, Frisard M, Roberts LJ II. Quantification of dinor,dihydro metabolites of F2-isoprostanes in urine by liquid chromatography/tandem mass spectrometry. Anal Biochem. 2006;348(2):185-191 (Pubitemid 41832522)
29. Naik AS, Kallapur SG, Bachurski CJ, et al. Effects of ventilation with different positive end-expiratory pressures on cytokine expression in the preterm lamb lung. Am J Respir Crit Care Med. 2001;164(3):494-498
30. Ehrenkranz RA, Walsh MC, Vohr BR, et al. Validation of National Institutes of Health consensus definition of bronchopulmonary dysplasia. Pediatrics. 2005;116(6):1353-1360 (Pubitemid 46056482)
31. Spanish Society for Neonatology, Neonatal Resuscitation Group. Manual de Reanimación Neonatal [Manual of Neonatal Resuscitation; in Spanish]. Madrid, Spain: Ergón Editores; 2006
32. O'Donnell CP, Kamlin CO, Davis PG, Morley CJ. Feasibility of and delay in obtaining pulse oximetry during neonatal resuscitation. J Pediatr. 2005;147(5):698-699
33. Fineman JR, Soifer SJ, Heymann MA. Regulation of pulmonary vascular tone in the perinatal period. Annu Rev Physiol. 1995;57:115-134
34. Asensi M, Sastre J, Pallardo FV, Garcia de la Asuncion J, Estrela JM, Viña J. A high-performance liquid chromatography method for measurement of oxidized glutathione in biological samples. Anal Biochem. 1994;217(2):323-328 (Pubitemid 24080768)
35. Riffenburgh RH. Statistics in Medicine. 2nd ed. New York, NY: Academic Press; 2005
36. Hansen-Pupp I, Hallin AL, Hellström-Westas L, et al. Inflammation at birth is associated with subnormal development in very preterm infants. Pediatr Res. 2008;64(2):183-188
37. Thiel M, Chouker A, Ohta A, et al. Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury. PLoS Biol. 2005;3(6):e174 (Pubitemid 41032218)
38. Deng H, Mason SN, Auten RL Jr. Lung inflammation in hyperoxia can be prevented by antichemokine treatment in newborn rats. Am J Respir Crit Care Med. 2000;162(6):2316-2323 (Pubitemid 32051706)
39. Cho H-Y, Morgan DL, Bauer AK, Kleeberger SR. Signal transduction pathways of tumor necrosis factor-mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med. 2007;175(8): 829-839
40. 2A signaling. Prog Neurobiol. 2007;83(5):263-276
41. Borrá s C, Esteve JM, Viña JR, Sastre J, Viña J, Pallardo FV. Gutathione regulates telomerase activity in 3T3 fibroblasts. J Biol Chem. 2004;279(33):34332-34335
42. Markovic J, Borras C, Ortega A, Sastre J, Viña J, Pallardo FV. Glutathione is recruited into the nucleus in early phases of cell proliferation. J Biol Chem. 2007;282(28):20416-20424 (Pubitemid 47099986)
43. Ogihara T, Hirano K, Ogihara H, et al. Non-protein transition metals and hydroxyl radical generation in cerebrospinal fluid of newborn infants with hypoxic-ischemic encephalopathy. Pediatr Res. 2003;53(4):594-599 (Pubitemid 36406729)
44. Montuschi P, Barnes PJ, Roberts LJ. Isoprostanes: markers and mediators of oxidative stress. FASEB J. 2004;18(15):1791-1800 (Pubitemid 39602265)
45. Patel M, Liang LP, Hou H, et al. Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension. J Neurochem. 2008; 104(1):264-270 (Pubitemid 350265056)
46. Banks BA, Ischiropoulos H, McClelland M, Ballard PL, Ballard RA. Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia. Pediatrics. 1998;101(5):870-874 (Pubitemid 28204839)
47. Saugstad OD. Chronic lung disease: the role of oxidative stress. Biol Neonate. 1998;74(suppl 1):21-28 (Pubitemid 28425288)
48. Ahola T, Fellman V, Kjellmer I, Raivio KO, Lapatto R. Plasma 8-isoprostane is increased in preterm infants who develop bronchopulmonary dysplasia or periventricular leukomalacia. Pediatr Res. 2004;56(1):88-93 (Pubitemid 38808547)
49. 2-isoprostanes are poor prognostic indicators for the development of bronchopulmonary dysplasia. J Perinatol. 2007;27(5):303-306
50. Spector LG, Klebanoff MA, Feusner JH, Georgieff MK, Ross JA. Childhood cancer following neonatal oxygen supplementation. J Pediatr. 2005;147(1):27-31
51. Hitchler MJ, Domann FE. An epigenetic perspective on the free radical theory of development. Free Radic Biol Med. 2007;43(7):1023-1036 (Pubitemid 47302657)
52. International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol. 2005;123(7):991-999
53. Papile LA, Munsick-Bruno G, Schaefer A. Relationship of cerebral intraventricular hemorrhage and early childhood neurologic handicaps. J Pediatr. 1983;103(2):273-277
54. Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2001;163(7): 1723-1729