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Volumn 49, Issue 4, 2009, Pages 193-201

Neurogenesis as a therapeutic target for Alzheimer's disease;Neurogénesis como diana terapéutica para la enfermedad de Alzheimer

Author keywords

Alzheimer's disease; Environment; Hippocampus; Neurogenesis; Progenitor cell; Transplant

Indexed keywords

ADULT; ALZHEIMER DISEASE; BRAIN FUNCTION; HUMAN; NERVE CELL; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; REGULATORY MECHANISM; REVIEW;

EID: 70349232917     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.4904.2008632     Document Type: Review
Times cited : (6)

References (75)
  • 1
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • Altman J, Das GD. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 1965; 124: 319-335
    • (1965) J Comp Neurol , vol.124 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 3
    • 37649000279 scopus 로고    scopus 로고
    • Identificación de células madre en el cerebro adulto humano
    • García-Verdugo JM. Identificación de células madre en el cerebro adulto humano. Rev Neurol 2007; 44 (Supl 3): S11.
    • (2007) Rev Neurol , vol.44 , Issue.SUPPL. 3
    • García-Verdugo, J.M.1
  • 4
    • 0030979469 scopus 로고    scopus 로고
    • Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch F, García-Verdugo JM, Álvarez-Buylla A. Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 1997; 17: 5046-5061 (Pubitemid 27263818)
    • (1997) Journal of Neuroscience , vol.17 , Issue.13 , pp. 5046-5061
    • Doetsch, F.1    Garcia-Verdugo, J.M.2    Alvarez-Buylla, A.3
  • 5
    • 37549050593 scopus 로고    scopus 로고
    • Neurogénesis como estrategia terapéutica para regenerar el sistema nervioso central
    • Arias-Carrión O, Drucker-Colín R. Neurogénesis como estrategia terapéutica para regenerar el sistema nervioso central. Rev Neurol 2007; 45: 739-745
    • (2007) Rev Neurol , vol.45 , pp. 739-745
    • Arias-Carrión, O.1    Drucker-Colín, R.2
  • 6
    • 66549099504 scopus 로고    scopus 로고
    • The heterogeneity of adult neural stem cells and the emerging complexity of their niche
    • Nov 6 [Epub ahead of print]
    • Álvarez-Buylla A, Kohwi M, Nguyen TM, Merkle FT. The heterogeneity of adult neural stem cells and the emerging complexity of their niche. Cold Spring Harb Symp Quant Biol 2008; Nov 6 [Epub ahead of print].
    • (2008) Cold Spring Harb Symp Quant Biol
    • Álvarez-Buylla, A.1    Kohwi, M.2    Nguyen, T.M.3    Merkle, F.T.4
  • 8
    • 37749053530 scopus 로고    scopus 로고
    • Changes in adult neurogenesis in neurodegenerative diseases: Cause or consequence?
    • Thompson A, Boekhoorn K, Van Dam AM, Lucassen PJ. Changes in adult neurogenesis in neurodegenerative diseases: cause or consequence? Genes Brain Behav 2008; 7 (Suppl 1): 28-42.
    • (2008) Genes Brain Behav , vol.7 , Issue.SUPPL. 1 , pp. 28-42
    • Thompson, A.1    Boekhoorn, K.2    Van Dam, A.M.3    Lucassen, P.J.4
  • 9
    • 17044454588 scopus 로고    scopus 로고
    • Motor and cognitive recovery induced by bone marrow stem cells grafted to striatum and hippocampus of impaired aged rats: Functional and therapeutic considerations
    • DOI 10.1196/annals.1297.011
    • Fernández CI, Alberti E, Mendoza Y, Martínez L, Collazo J, Rosillo JC, et al. Motor and cognitive recovery induced by bone marrow stem cells grafted to striatum and hippocampus of impaired aged rats: functional and therapeutic considerations. Ann N Y Acad Sci 2004; 1019: 48-52. (Pubitemid 38951284)
    • (2004) Annals of the New York Academy of Sciences , vol.1019 , pp. 48-52
    • Fernandez, C.I.1    Alberti, E.2    Mendoza, Y.3    Martinez, L.4    Collazo, J.5    Rosillo, J.C.6    Bauza, J.Y.7
  • 10
    • 39349102866 scopus 로고    scopus 로고
    • Six3 controls the neural progenitor status in the murine CNS
    • DOI 10.1093/cercor/bhm092
    • Appolloni I, Calzolari F, Corte G, Perris R, Malatesta P. Six3 controls the neural progenitor status in the murine CNS. Cereb Cortex 2008; 18: 553-562 (Pubitemid 351264230)
    • (2008) Cerebral Cortex , vol.18 , Issue.3 , pp. 553-562
    • Appolloni, I.1    Calzolari, F.2    Corte, G.3    Perris, R.4    Malatesta, P.5
  • 11
    • 37249017951 scopus 로고    scopus 로고
    • Activation of subventricular zone stem cells after neuronal injury
    • DOI 10.1007/s00441-007-0451-1
    • Kim Y, Szele FG. Activation of subventricular zone stem cells after neuronal injury. Cell Tissue Res 2008; 331: 337-345 (Pubitemid 350265481)
    • (2008) Cell and Tissue Research , vol.331 , Issue.1 , pp. 337-345
    • Kim, Y.1    Szele, F.G.2
  • 12
    • 37749043746 scopus 로고    scopus 로고
    • Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation
    • Schindowski K, Belarbi K, Bretteville A, Ando K, Buee L. Neurogenesis and cell cycle-reactivated neuronal death during pathogenic tau aggregation. Genes Brain Behav 2008; 7 (Suppl 1): 92-100.
    • (2008) Genes Brain Behav , vol.7 , Issue.SUPPL. 1 , pp. 92-100
    • Schindowski, K.1    Belarbi, K.2    Bretteville, A.3    Ando, K.4    Buee, L.5
  • 14
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • DOI 10.1016/S0092-8674(00)80783-7
    • Doetsch F, Caille I, Lim DA, García-Verdugo JM, Álvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999; 97: 703-716 (Pubitemid 29278045)
    • (1999) Cell , vol.97 , Issue.6 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 16
    • 0037986366 scopus 로고    scopus 로고
    • Postnatal development of radial glia and the ventricular zone (VZ): A continuum of the neural stem cell compartment
    • DOI 10.1093/cercor/13.6.580
    • Tramontin AD, García-Verdugo JM, Lim DA, Álvarez-Buylla A. Post-natal development of radial glia and the ventricular zone (VZ): a continuum of the neural stem cell compartment. Cereb Cortex 2003; 13: 580-587 (Pubitemid 36613164)
    • (2003) Cerebral Cortex , vol.13 , Issue.6 , pp. 580-587
    • Tramontin, A.D.1    Garcia-Verdugo, J.M.2    Lim, D.A.3    Alvarez-Buylla, A.4
  • 17
    • 1542268981 scopus 로고    scopus 로고
    • For the long run: Maintaining germinal niches in the adult brain
    • DOI 10.1016/S0896-6273(04)00111-4, PII S0896627304001114
    • Álvarez-Buylla A, Lim DA. For the long run: maintaining germinal niches in the adult brain. Neuron 2004; 41: 683-686 (Pubitemid 38326831)
    • (2004) Neuron , vol.41 , Issue.5 , pp. 683-686
    • Alvarez-Buylla, A.1    Lim, D.A.2
  • 18
    • 0027410493 scopus 로고
    • Neurons, astrocytes, and oligodendrocytes of the rat cerebral cortex originate from separate progenitor cells: An ultrastructural analysis of clonally related cells
    • Luskin MB, Parnavelas JG, Barfield JA. Neurons, astrocytes, and oligodendrocytes of the rat cerebral cortex originate from separate progenitor cells: an ultrastructural analysis of clonally related cells. J Neurosci 1993; 13: 1730-1750
    • (1993) J Neurosci , vol.13 , pp. 1730-1750
    • Luskin, M.B.1    Parnavelas, J.G.2    Barfield, J.A.3
  • 19
    • 34247113877 scopus 로고    scopus 로고
    • Human cortical neurons originate from radial glia and neuron-restricted progenitors
    • DOI 10.1523/JNEUROSCI.0111-07.2007
    • Mo Z, Moore AR, Filipovic R, Ogawa Y, Kazuhiro I, Antic SD, et al. Human cortical neurons originate from radial glia and neuron-restricted progenitors. J Neurosci 2007; 27: 4132-4145 (Pubitemid 46597153)
    • (2007) Journal of Neuroscience , vol.27 , Issue.15 , pp. 4132-4145
    • Mo, Z.1    Moore, A.R.2    Filipovic, R.3    Ogawa, Y.4    Kazuhiro, I.5    Antic, S.D.6    Zecevic, N.7
  • 20
    • 17044447617 scopus 로고    scopus 로고
    • Environmental enrichment-behavior-oxidative stress interactions in the aged rat: Issues for a therapeutic approach in human aging
    • DOI 10.1196/annals.1297.012
    • Fernández CI, Collazo J, Bauza Y, Castellanos MR, Lopez O. Environmental enrichment-behavior-oxidative stress interactions in the aged rat: issues for a therapeutic approach in human aging. Ann N Y Acad Sci 2004; 1019: 53-57 (Pubitemid 38951285)
    • (2004) Annals of the New York Academy of Sciences , vol.1019 , pp. 53-57
    • Fernandez, C.I.1    Collazo, J.2    Bauza, Y.3    Castellanos, M.R.4    Lopez, O.5
  • 22
    • 0036458427 scopus 로고    scopus 로고
    • Neurogenesis in adult primates
    • Rakic P. Neurogenesis in adult primates. Prog Brain Res 2002; 138: 3-14.
    • (2002) Prog Brain Res , vol.138 , pp. 3-14
    • Rakic, P.1
  • 24
    • 38549090692 scopus 로고    scopus 로고
    • The impact of maternal separation on adult mouse behaviour and on the total neuron number in the mouse hippocampus
    • DOI 10.1007/s00429-007-0169-6
    • Fabricius K, Wortwein G, Pakkenberg B. The impact of maternal separation on adult mouse behaviour and on the total neuron number in the mouse hippocampus. Brain Struct Funct 2008; 212: 403-416 (Pubitemid 351161499)
    • (2008) Brain Structure and Function , vol.212 , Issue.5 , pp. 403-416
    • Fabricius, K.1    Wortwein, G.2    Pakkenberg, B.3
  • 25
    • 67649646786 scopus 로고    scopus 로고
    • Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice
    • Jan 12 [Epub ahead of print]
    • Thuret S, Toni N, Aigner S, Yeo GW, Gage FH. Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. Hippocampus 2009; Jan 12 [Epub ahead of print].
    • (2009) Hippocampus
    • Thuret, S.1    Toni, N.2    Aigner, S.3    Yeo, G.W.4    Gage, F.H.5
  • 27
    • 55049119613 scopus 로고    scopus 로고
    • Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator
    • Osumi N, Shinohara H, Numayama-Tsuruta K, Maekawa M. Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator. Stem Cells 2008; 26: 1663-1672
    • (2008) Stem Cells , vol.26 , pp. 1663-1672
    • Osumi, N.1    Shinohara, H.2    Numayama-Tsuruta, K.3    Maekawa, M.4
  • 28
    • 40949107902 scopus 로고    scopus 로고
    • Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis
    • Iulianella A, Sharma M, Durnin M, Vanden Heuvel GB, Trainor PA. Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis. Development 2008; 135: 729-741
    • (2008) Development , vol.135 , pp. 729-741
    • Iulianella, A.1    Sharma, M.2    Durnin, M.3    Vanden Heuvel, G.B.4    Trainor, P.A.5
  • 29
    • 42149167968 scopus 로고    scopus 로고
    • Meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye
    • Bessa J, Tavares MJ, Santos J, Kikuta H, Laplante M, Becker TS, et al. meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development 2008; 135: 799-803.
    • (2008) Development , vol.135 , pp. 799-803
    • Bessa, J.1    Tavares, M.J.2    Santos, J.3    Kikuta, H.4    Laplante, M.5    Becker, T.S.6
  • 30
    • 38349062692 scopus 로고    scopus 로고
    • c-Myb is required for neural progenitor cell proliferation and maintenance of the neural stem cell niche in adult brain
    • Malaterre J, Mantamadiotis T, Dworkin S, Lightowler S, Yang Q, Ransome MI, et al. c-Myb is required for neural progenitor cell proliferation and maintenance of the neural stem cell niche in adult brain. Stem Cells 2008; 26: 173-181
    • (2008) Stem Cells , vol.26 , pp. 173-181
    • Malaterre, J.1    Mantamadiotis, T.2    Dworkin, S.3    Lightowler, S.4    Yang, Q.5    Ransome, M.I.6
  • 31
    • 45749090170 scopus 로고    scopus 로고
    • Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals
    • Jiao J, Chen DF. Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals. Stem Cells 2008; 26: 1221-1230
    • (2008) Stem Cells , vol.26 , pp. 1221-1230
    • Jiao, J.1    Chen, D.F.2
  • 32
    • 34247516494 scopus 로고    scopus 로고
    • Wnt expression in the adult rat subventricular zone after stroke
    • DOI 10.1016/j.neulet.2007.03.039, PII S0304394007003163
    • Morris DC, Zhang ZG, Wang Y, Zhang RL, Gregg S, Liu XS, et al. Wnt expression in the adult rat subventricular zone after stroke. Neurosci Lett 2007; 418: 170-174 (Pubitemid 46656428)
    • (2007) Neuroscience Letters , vol.418 , Issue.2 , pp. 170-174
    • Morris, D.C.1    Zhang, Z.G.2    Wang, Y.3    Zhang, R.L.4    Gregg, S.5    Liu, X.S.6    Chopp, M.7
  • 33
    • 33847219581 scopus 로고    scopus 로고
    • Stroke induces gene profile changes associated with neurogenesis and angiogenesis in adult subventricular zone progenitor cells
    • DOI 10.1038/sj.jcbfm.9600371, PII 9600371
    • Liu XS, Zhang ZG, Zhang RL, Gregg S, Morris DC, Wang Y, et al. Stroke induces gene profile changes associated with neurogenesis and angiogenesis in adult subventricular zone progenitor cells. J Cereb Blood Flow Metab 2007; 27: 564-574 (Pubitemid 46310437)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.3 , pp. 564-574
    • Liu, X.S.1    Zhang, Z.G.2    Zhang, R.L.3    Gregg, S.4    Morris, D.C.5    Wang, Y.6    Chopp, M.7
  • 35
    • 23844520707 scopus 로고    scopus 로고
    • Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs
    • DOI 10.1111/j.1365-2443.2005.00876.x
    • Kasai M, Satoh K, Akiyama T. Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs. Genes Cells 2005; 10: 777-783 (Pubitemid 41158736)
    • (2005) Genes to Cells , vol.10 , Issue.8 , pp. 777-783
    • Kasai, M.1    Satoh, K.2    Akiyama, T.3
  • 38
    • 41149108621 scopus 로고    scopus 로고
    • Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus
    • Kao HT, Li P, Chao HM, Janoschka S, Pham K, Feng J, et al. Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus. J Comp Neurol 2008; 507: 1860-1870
    • (2008) J Comp Neurol , vol.507 , pp. 1860-1870
    • Kao, H.T.1    Li, P.2    Chao, H.M.3    Janoschka, S.4    Pham, K.5    Feng, J.6
  • 39
    • 42049112734 scopus 로고    scopus 로고
    • MAPKs as mediators of cell fate determination: An approach to neurodegenerative diseases
    • Miloso M, Scuteri A, Foudah D, Tredici G. MAPKs as mediators of cell fate determination: an approach to neurodegenerative diseases. Curr Med Chem 2008; 15: 538-548
    • (2008) Curr Med Chem , vol.15 , pp. 538-548
    • Miloso, M.1    Scuteri, A.2    Foudah, D.3    Tredici, G.4
  • 40
    • 34548833893 scopus 로고    scopus 로고
    • Substance P is a promoter of adult neural progenitor cell proliferation under normal and ischemic conditions
    • DOI 10.3171/JNS-07/09/0593
    • Park SW, Yan YP, Satriotomo I, Vemuganti R, Dempsey RJ. Substance P is a promoter of adult neural progenitor cell proliferation under normal and ischemic conditions. J Neurosurg 2007; 107: 593-599 (Pubitemid 47451044)
    • (2007) Journal of Neurosurgery , vol.107 , Issue.3 , pp. 593-599
    • Park, S.-W.1    Yan, Y.-P.2    Satriotomo, I.3    Vemuganti, R.4    Dempsey, R.J.5
  • 43
    • 0042362874 scopus 로고    scopus 로고
    • Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
    • DOI 10.1046/j.1471-4159.2002.01267.x
    • Haughey NJ, Nath A, Chan SL, Borchard AC, Rao MS, Mattson MP. Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem 2002; 83: 1509-1524 (Pubitemid 35477489)
    • (2002) Journal of Neurochemistry , vol.83 , Issue.6 , pp. 1509-1524
    • Haughey, N.J.1    Nath, A.2    Chan, S.L.3    Borchard, A.C.4    Rao, M.S.5    Mattson, M.P.6
  • 44
    • 34250815052 scopus 로고    scopus 로고
    • Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis
    • DOI 10.1523/JNEUROSCI.5564-06.2007
    • Verret L, Jankowsky JL, Xu GM, Borchelt DR, Rampon C. Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci 2007; 27: 6771-6780 (Pubitemid 46983445)
    • (2007) Journal of Neuroscience , vol.27 , Issue.25 , pp. 6771-6780
    • Verret, L.1    Jankowsky, J.L.2    Xu, G.M.3    Borchelt, D.R.4    Rampon, C.5
  • 45
    • 40449103490 scopus 로고    scopus 로고
    • Mechanism of glial differentiation of neural progenitor cells by amyloid precursor protein
    • DOI 10.1159/000113693
    • Sugaya K. Mechanism of glial differentiation of neural progenitor cells by amyloid precursor protein. Neurodegener Dis 2008; 5: 170-172 (Pubitemid 351347841)
    • (2008) Neurodegenerative Diseases , vol.5 , Issue.3-4 , pp. 170-172
    • Sugaya, K.1
  • 47
    • 33748790666 scopus 로고    scopus 로고
    • Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus
    • DOI 10.1016/j.nbd.2006.04.017, PII S0969996106000957
    • Boekhoorn K, Joels M, Lucassen PJ. Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus. Neurobiol Dis 2006; 24: 1-14. (Pubitemid 44416208)
    • (2006) Neurobiology of Disease , vol.24 , Issue.1 , pp. 1-14
    • Boekhoorn, K.1    Joels, M.2    Lucassen, P.J.3
  • 48
    • 36749010157 scopus 로고    scopus 로고
    • Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin
    • Verwer RW, Sluiter AA, Balesar RA, Baayen JC, Noske DP, Dirven CM, et al. Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin. Brain 2007; 130 (Pt 12): 3321-3335
    • (2007) Brain , vol.130 , Issue.PART 12 , pp. 3321-3335
    • Verwer, R.W.1    Sluiter, A.A.2    Balesar, R.A.3    Baayen, J.C.4    Noske, D.P.5    Dirven, C.M.6
  • 49
    • 67651119420 scopus 로고    scopus 로고
    • Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor
    • Mar 26 [Epub ahead of print]
    • Sotthibundhu A, Li QX, Thangnipon W, Coulson EJ. Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor. Neurobiol Aging 2008; Mar 26 [Epub ahead of print].
    • (2008) Neurobiol Aging
    • Sotthibundhu, A.1    Li, Q.X.2    Thangnipon, W.3    Coulson, E.J.4
  • 50
    • 33847258237 scopus 로고    scopus 로고
    • Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
    • DOI 10.1016/j.expneurol.2006.09.018, PII S0014488606005565
    • Zhang C, McNeil E, Dressler L, Siman R. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp Neurol 2007; 204: 77-87. (Pubitemid 46330258)
    • (2007) Experimental Neurology , vol.204 , Issue.1 , pp. 77-87
    • Zhang, C.1    McNeil, E.2    Dressler, L.3    Siman, R.4
  • 59
    • 49249116020 scopus 로고    scopus 로고
    • Behavior of neural stem cells in the Alzheimer brain
    • Waldau B, Shetty AK. Behavior of neural stem cells in the Alzheimer brain. Cell Mol Life Sci 2008; 65: 2372-2384
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2372-2384
    • Waldau, B.1    Shetty, A.K.2
  • 60
    • 0037362773 scopus 로고    scopus 로고
    • The dentate gyrus neurogenesis: A therapeutic target for Alzheimer's disease
    • Tatebayashi Y, Lee MH, Li L, Iqbal K, Grundke-Iqbal I. The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol 2003; 105: 225-232 (Pubitemid 36798813)
    • (2003) Acta Neuropathologica , vol.105 , Issue.3 , pp. 225-232
    • Tatebayashi, Y.1    Lee, M.H.2    Li, L.3    Iqbal, K.4    Grundke-Iqbal, I.5
  • 61
    • 33745591621 scopus 로고    scopus 로고
    • Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: Allopregnanolone as a proof of concept neurogenic agent
    • Brinton RD, Wang JM. Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent. Curr Alzheimer Res 2006; 3: 185-190
    • (2006) Curr Alzheimer Res , vol.3 , pp. 185-190
    • Brinton, R.D.1    Wang, J.M.2
  • 62
    • 44449160372 scopus 로고    scopus 로고
    • Intraventricular nerve growth factor infusion improves cerebral blood flow and stimulates doublecortin expression in two infants with hypoxic-ischemic brain injury
    • DOI 10.1179/016164107X247948
    • Chiaretti A, Antonelli A, Genovese O, Fernández E, Giuda D, Mariotti P, et al. Intraventricular nerve growth factor infusion improves cerebral blood flow and stimulates doublecortin expression in two infants with hypoxic-ischemic brain injury. Neurol Res 2008; 30: 223-228 (Pubitemid 351769412)
    • (2008) Neurological Research , vol.30 , Issue.3 , pp. 223-228
    • Chiaretti, A.1    Antonelli, A.2    Genovese, O.3    Fernandez, E.4    Di Giuda, D.5    Mariotti, P.6    Riccardi, R.7
  • 63
    • 34250328767 scopus 로고    scopus 로고
    • G-CSF rescues the memory impairment of animal models of Alzheimer's disease
    • DOI 10.1084/jem.20062481
    • Tsai KJ, Tsai YC, Shen CK. G-CSF rescues the memory impairment of animal models of Alzheimer's disease. J Exp Med 2007; 204: 1273-1280 (Pubitemid 46919864)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.6 , pp. 1273-1280
    • Tsai, K.-J.1    Tsai, Y.-C.2    Shen, C.-K.J.3
  • 66
    • 44849119265 scopus 로고    scopus 로고
    • Activin in the brain modulates anxiety-related behavior and adult neurogenesis
    • DOI 10.1371/journal.pone.0001869
    • Ageta H, Murayama A, Migishima R, Kida S, Tsuchida K, Yokoyama M, et al. Activin in the brain modulates anxiety-related behavior and adult neurogenesis. PLoS ONE 2008; 3: e1869. (Pubitemid 351943832)
    • (2008) PLoS ONE , vol.3 , Issue.4
    • Ageta, H.1    Murayama, A.2    Migishima, R.3    Kida, S.4    Tsuchida, K.5    Yokoyama, M.6    Inokuchi, K.7
  • 67
    • 19044383923 scopus 로고    scopus 로고
    • Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: Effects in behavioral models
    • Dow AL, Russell DS, Duman RS. Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models. J Neurosci 2005; 25: 4908-4916
    • (2005) J Neurosci , vol.25 , pp. 4908-4916
    • Dow, A.L.1    Russell, D.S.2    Duman, R.S.3
  • 69
    • 38149072468 scopus 로고    scopus 로고
    • Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke
    • Shyu WC, Lin SZ, Chiang MF, Chen DC, Su CY, Wang HJ, et al. Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke. J Clin Invest 2008; 118: 133-148
    • (2008) J Clin Invest , vol.118 , pp. 133-148
    • Shyu, W.C.1    Lin, S.Z.2    Chiang, M.F.3    Chen, D.C.4    Su, C.Y.5    Wang, H.J.6
  • 70
    • 33846203884 scopus 로고    scopus 로고
    • Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation
    • DOI 10.1111/j.1460-9568.2006.05269.x
    • Fan Y, Liu Z, Weinstein PR, Fike JR, Liu J. Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation. Eur J Neurosci 2007; 25: 38-46. (Pubitemid 46096221)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.1 , pp. 38-46
    • Fan, Y.1    Liu, Z.2    Weinstein, P.R.3    Fike, J.R.4    Liu, J.5
  • 71
    • 38649092266 scopus 로고    scopus 로고
    • IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
    • Koo JW, Duman RS. IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci U S A 2008; 105: 751-756
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 751-756
    • Koo, J.W.1    Duman, R.S.2
  • 72
    • 39049146540 scopus 로고    scopus 로고
    • Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse
    • DOI 10.1111/j.1460-9568.2008.06050.x
    • Spulber S, Oprica M, Bartfai T, Winblad B, Schultzberg M. Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse. Eur J Neurosci 2008; 27: 549-558 (Pubitemid 351239305)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.3 , pp. 549-558
    • Spulber, S.1    Oprica, M.2    Bartfai, T.3    Winblad, B.4    Schultzberg, M.5
  • 73
    • 39149100691 scopus 로고    scopus 로고
    • Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca(v)1-channel activity
    • Piacentini R, Ripoli C, Mezzogori D, Azzena GB, Grassi C. Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca(v)1-channel activity. J Cell Physiol 2008; 215: 129-139
    • (2008) J Cell Physiol , vol.215 , pp. 129-139
    • Piacentini, R.1    Ripoli, C.2    Mezzogori, D.3    Azzena, G.B.4    Grassi, C.5
  • 74
    • 34547824397 scopus 로고    scopus 로고
    • EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease
    • DOI 10.1096/fj.06-7649com
    • Tchantchou F, Xu Y, Wu Y, Christen Y, Luo Y. EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease. FASEB J 2007; 21: 2400-2408 (Pubitemid 47230670)
    • (2007) FASEB Journal , vol.21 , Issue.10 , pp. 2400-2408
    • Tchantchou, F.1    Xu, Y.2    Wu, Y.3    Christen, Y.4    Luo, Y.5
  • 75
    • 48349108505 scopus 로고    scopus 로고
    • Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets
    • Panchal HD, Vranizan K, Lee CY, Ho J, Ngai J, Timiras PS. Early anti-oxidative and anti-proliferative curcumin effects on neuroglioma cells suggest therapeutic targets. Neurochem Res 2008; 33: 1701-1710
    • (2008) Neurochem Res , vol.33 , pp. 1701-1710
    • Panchal, H.D.1    Vranizan, K.2    Lee, C.Y.3    Ho, J.4    Ngai, J.5    Timiras, P.S.6


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