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Volumn 94, Issue 1, 2009, Pages 56-62

Neuroprotective profile of dextromethorphan in an experimental model of penetrating ballistic-like brain injury

Author keywords

Cognitive; Dextromethorphan; DM; Motor; NOR; Novel object recognition; PBBI; Penetrating ballistic like brain injury; TBI; Traumatic brain injury

Indexed keywords

DEXTROMETHORPHAN;

EID: 70349220780     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.07.006     Document Type: Article
Times cited : (20)

References (33)
  • 1
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination
    • Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., and Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17 (1986) 472-476
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 2
    • 68049097187 scopus 로고    scopus 로고
    • Military traumatic brain and spinal column injury: a 5-year study of the impact blast and other military grade weaponry on the central nervous system
    • Bell R.S., Vo A.H., Neal C.J., Tigno J., Roberts R., Mossop C., et al. Military traumatic brain and spinal column injury: a 5-year study of the impact blast and other military grade weaponry on the central nervous system. Trauma 66 (2009) S104-111
    • (2009) Trauma , vol.66
    • Bell, R.S.1    Vo, A.H.2    Neal, C.J.3    Tigno, J.4    Roberts, R.5    Mossop, C.6
  • 3
    • 0023832809 scopus 로고
    • Dextromethorphan and dextrorphan as calcium channel antagonists
    • Carpenter C.L., Marks S.S., Watson D.L., and Greenberg D.A. Dextromethorphan and dextrorphan as calcium channel antagonists. Brain Res 439 (1988) 372-375
    • (1988) Brain Res , vol.439 , pp. 372-375
    • Carpenter, C.L.1    Marks, S.S.2    Watson, D.L.3    Greenberg, D.A.4
  • 4
    • 0023124547 scopus 로고
    • Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity
    • Choi D.W. Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity. Brain Res 403 (1987) 333-336
    • (1987) Brain Res , vol.403 , pp. 333-336
    • Choi, D.W.1
  • 5
    • 0032828687 scopus 로고    scopus 로고
    • The dependence of span and delayed-response performance on prefrontal cortex
    • D'Esposito M., and Postle B.R. The dependence of span and delayed-response performance on prefrontal cortex. Neuropsychologia 37 (1999) 1303-1315
    • (1999) Neuropsychologia , vol.37 , pp. 1303-1315
    • D'Esposito, M.1    Postle, B.R.2
  • 6
    • 0034046481 scopus 로고    scopus 로고
    • Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies
    • D'Esposito M., Postle B.R., and Rypma B. Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies. Exp Brain Res 133 (2000) 3-11
    • (2000) Exp Brain Res , vol.133 , pp. 3-11
    • D'Esposito, M.1    Postle, B.R.2    Rypma, B.3
  • 8
    • 0034089325 scopus 로고    scopus 로고
    • The central role of the prefrontal cortex in directing attention to novel events
    • Daffner K.R., Mesulam M.M., Scinto L.F., Acar D., Calvo V., Faust R., et al. The central role of the prefrontal cortex in directing attention to novel events. Brain 123 Pt 5 (2000) 927-939
    • (2000) Brain , vol.123 , Issue.PART 5 , pp. 927-939
    • Daffner, K.R.1    Mesulam, M.M.2    Scinto, L.F.3    Acar, D.4    Calvo, V.5    Faust, R.6
  • 9
    • 0028967328 scopus 로고
    • Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures
    • DeCoster M.A., Klette K.L., Knight E.S., and Tortella F.C. Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures. Brain Res 671 (1995) 45-53
    • (1995) Brain Res , vol.671 , pp. 45-53
    • DeCoster, M.A.1    Klette, K.L.2    Knight, E.S.3    Tortella, F.C.4
  • 10
    • 0030110801 scopus 로고    scopus 로고
    • Divided and focused attention in patients with lesion of the prefrontal cortex
    • Godefroy O., and Rousseaux M. Divided and focused attention in patients with lesion of the prefrontal cortex. Brain Cogn 30 (1996) 155-174
    • (1996) Brain Cogn , vol.30 , pp. 155-174
    • Godefroy, O.1    Rousseaux, M.2
  • 11
    • 0030763438 scopus 로고    scopus 로고
    • Novel decision making in patients with prefrontal or posterior brain damage
    • Godefroy O., and Rousseaux M. Novel decision making in patients with prefrontal or posterior brain damage. Neurology 49 (1997) 695-701
    • (1997) Neurology , vol.49 , pp. 695-701
    • Godefroy, O.1    Rousseaux, M.2
  • 12
    • 0023189753 scopus 로고
    • Dextrorphan and dextromethorphan attenuate hypoxic injury in neuronal culture
    • Goldberg M.P., Pham P.C., and Choi D.W. Dextrorphan and dextromethorphan attenuate hypoxic injury in neuronal culture. Neurosci Lett 80 (1987) 11-15
    • (1987) Neurosci Lett , vol.80 , pp. 11-15
    • Goldberg, M.P.1    Pham, P.C.2    Choi, D.W.3
  • 13
    • 33751186935 scopus 로고    scopus 로고
    • Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia
    • Katnik C., Guerrero W.R., Pennypacker K.R., Herrera Y., and Cuevas J. Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. J Pharmacol Exp Ther 319 (2006) 1355-1365
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1355-1365
    • Katnik, C.1    Guerrero, W.R.2    Pennypacker, K.R.3    Herrera, Y.4    Cuevas, J.5
  • 14
    • 0028884779 scopus 로고
    • Role of calcium in sigma-mediated neuroprotection in rat primary cortical neurons
    • Klette K.L., DeCoster M.A., Moreton J.E., and Tortella F.C. Role of calcium in sigma-mediated neuroprotection in rat primary cortical neurons. Brain Res 704 (1995) 31-41
    • (1995) Brain Res , vol.704 , pp. 31-41
    • Klette, K.L.1    DeCoster, M.A.2    Moreton, J.E.3    Tortella, F.C.4
  • 15
    • 0030903679 scopus 로고    scopus 로고
    • Neuroprotective sigma ligands attenuate NMDA and trans-ACPD-induced calcium signaling in rat primary neurons
    • Klette K.L., Lin Y., Clapp L.E., DeCoster M.A., Moreton J.E., and Tortella F.C. Neuroprotective sigma ligands attenuate NMDA and trans-ACPD-induced calcium signaling in rat primary neurons. Brain Res 756 (1997) 231-240
    • (1997) Brain Res , vol.756 , pp. 231-240
    • Klette, K.L.1    Lin, Y.2    Clapp, L.E.3    DeCoster, M.A.4    Moreton, J.E.5    Tortella, F.C.6
  • 16
    • 59849088006 scopus 로고    scopus 로고
    • NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury
    • Lu X.C., Chen R.W., Yao C., Wei H., Yang X., Liao Z., et al. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. J Neurotrauma (2009)
    • (2009) J Neurotrauma
    • Lu, X.C.1    Chen, R.W.2    Yao, C.3    Wei, H.4    Yang, X.5    Liao, Z.6
  • 18
    • 0035660075 scopus 로고    scopus 로고
    • The interaction between neuroactive steroids and the sigma1 receptor function: behavioral consequences and therapeutic opportunities
    • Maurice T., Urani A., Phan V.L., and Romieu P. The interaction between neuroactive steroids and the sigma1 receptor function: behavioral consequences and therapeutic opportunities. Brain Res Brain Res Rev 37 (2001) 116-132
    • (2001) Brain Res Brain Res Rev , vol.37 , pp. 116-132
    • Maurice, T.1    Urani, A.2    Phan, V.L.3    Romieu, P.4
  • 19
    • 0029059649 scopus 로고
    • Pharmacokinetics of dextromethorphan and metabolites in humans: influence of the CYP2D6 phenotype and quinidine inhibition
    • Schadel M., Wu D., Otton S.V., Kalow W., and Sellers E.M. Pharmacokinetics of dextromethorphan and metabolites in humans: influence of the CYP2D6 phenotype and quinidine inhibition. J Clin Psychopharmacol 15 (1995) 263-269
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 263-269
    • Schadel, M.1    Wu, D.2    Otton, S.V.3    Kalow, W.4    Sellers, E.M.5
  • 20
    • 0030574257 scopus 로고    scopus 로고
    • Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats
    • Senda T., Matsuno K., Okamoto K., Kobayashi T., Nakata K., and Mita S. Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats. Eur J Pharmacol 315 (1996) 1-10
    • (1996) Eur J Pharmacol , vol.315 , pp. 1-10
    • Senda, T.1    Matsuno, K.2    Okamoto, K.3    Kobayashi, T.4    Nakata, K.5    Mita, S.6
  • 21
    • 0029876331 scopus 로고    scopus 로고
    • Dose escalation safety and tolerance study of the N-methyl-d-aspartate antagonist dextromethorphan in neurosurgery patients
    • Steinberg G.K., Bell T.E., and Yenari M.A. Dose escalation safety and tolerance study of the N-methyl-d-aspartate antagonist dextromethorphan in neurosurgery patients. J Neurosurg 84 (1996) 860-866
    • (1996) J Neurosurg , vol.84 , pp. 860-866
    • Steinberg, G.K.1    Bell, T.E.2    Yenari, M.A.3
  • 22
    • 0024397972 scopus 로고
    • Dextromethorphan and neuromodulation: old drug coughs up new activities
    • Tortella F.C., Pellicano M., and Bowery N.G. Dextromethorphan and neuromodulation: old drug coughs up new activities. Trends Pharmacol Sci 10 (1989) 501-507
    • (1989) Trends Pharmacol Sci , vol.10 , pp. 501-507
    • Tortella, F.C.1    Pellicano, M.2    Bowery, N.G.3
  • 23
    • 0032849033 scopus 로고    scopus 로고
    • Neuroprotection (focal ischemia) and neurotoxicity (electroencephalographic) studies in rats with AHN649, a 3-amino analog of dextromethorphan and low-affinity N-methyl-d-aspartate antagonist
    • Tortella F.C., Britton P., Williams A., Lu X.C., and Newman A.H. Neuroprotection (focal ischemia) and neurotoxicity (electroencephalographic) studies in rats with AHN649, a 3-amino analog of dextromethorphan and low-affinity N-methyl-d-aspartate antagonist. J Pharmacol Exp Ther 291 (1999) 399-408
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 399-408
    • Tortella, F.C.1    Britton, P.2    Williams, A.3    Lu, X.C.4    Newman, A.H.5
  • 24
    • 0024454824 scopus 로고
    • An open label trial of dextromethorphan in Huntington's disease
    • Walker F.O., and Hunt V.P. An open label trial of dextromethorphan in Huntington's disease. Clin Neuropharmacol 12 (1989) 322-330
    • (1989) Clin Neuropharmacol , vol.12 , pp. 322-330
    • Walker, F.O.1    Hunt, V.P.2
  • 26
    • 34548585105 scopus 로고    scopus 로고
    • Dextromethorphan as a potential neuroprotective agent with unique mechanisms of action
    • Werling L.L., Lauterbach E.C., and Calef U. Dextromethorphan as a potential neuroprotective agent with unique mechanisms of action. Neurologist 13 (2007) 272-293
    • (2007) Neurologist , vol.13 , pp. 272-293
    • Werling, L.L.1    Lauterbach, E.C.2    Calef, U.3
  • 27
    • 0033933764 scopus 로고    scopus 로고
    • Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-d-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies
    • Williams A.J., Dave J.R., Phillips J.B., Lin Y., McCabe R.T., and Tortella F.C. Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-d-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies. J Pharmacol Exp Ther 294 (2000) 378-386
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 378-386
    • Williams, A.J.1    Dave, J.R.2    Phillips, J.B.3    Lin, Y.4    McCabe, R.T.5    Tortella, F.C.6
  • 29
    • 33845915777 scopus 로고    scopus 로고
    • Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration
    • Williams A.J., Hartings J.A., Lu X.C., Rolli M.L., and Tortella F.C. Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration. J Neurotrauma 23 (2006) 1828-1846
    • (2006) J Neurotrauma , vol.23 , pp. 1828-1846
    • Williams, A.J.1    Hartings, J.A.2    Lu, X.C.3    Rolli, M.L.4    Tortella, F.C.5
  • 30
    • 33749521583 scopus 로고    scopus 로고
    • Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the rat
    • Williams A.J., Ling G.S., and Tortella F.C. Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the rat. Neurosci Lett 408 (2006) 183-188
    • (2006) Neurosci Lett , vol.408 , pp. 183-188
    • Williams, A.J.1    Ling, G.S.2    Tortella, F.C.3
  • 31
    • 34547808199 scopus 로고    scopus 로고
    • Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat
    • Williams A.J., Wei H.H., Dave J.R., and Tortella F.C. Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat. J Neuroinflammation 4 (2007) 17
    • (2007) J Neuroinflammation , vol.4 , pp. 17
    • Williams, A.J.1    Wei, H.H.2    Dave, J.R.3    Tortella, F.C.4
  • 32
    • 0036085710 scopus 로고    scopus 로고
    • Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons
    • Zhang H., and Cuevas J. Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons. J Neurophysiol 87 (2002) 2867-2879
    • (2002) J Neurophysiol , vol.87 , pp. 2867-2879
    • Zhang, H.1    Cuevas, J.2
  • 33
    • 0025872460 scopus 로고
    • Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain
    • Zhou G.Z., and Musacchio J.M. Computer-assisted modeling of multiple dextromethorphan and sigma binding sites in guinea pig brain. Eur J Pharmacol 206 (1991) 261-269
    • (1991) Eur J Pharmacol , vol.206 , pp. 261-269
    • Zhou, G.Z.1    Musacchio, J.M.2


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