Endocytic control of ion channel density as a target for cardiovascular disease

Journal of Clinical Investigation

Volumn 119, Issue 9, 2009, Pages 2531-2534

  Robertson, Gail A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELAYED RECTIFIER POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM ION; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL M4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; UNCLASSIFIED DRUG;

CARDIOVASCULAR DISEASE; ELECTROLYTE DISTURBANCE; ENDOCYTOBIOSIS; GENE MUTATION; HEART MUSCLE CELL; HEART VENTRICLE ARRHYTHMIA; HUMAN; HUMAN CELL; HYPOKALEMIA; ION TRANSPORT; LONG QT SYNDROME; LYSOSOME; NOTE; PRIORITY JOURNAL; RABBIT; SUMOYLATION; UBIQUITINATION;

ANIMALS; ARRHYTHMIAS, CARDIAC; CARDIOVASCULAR DISEASES; CELL LINE; ENDOCYTOSIS; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; HYPOKALEMIA; ION CHANNELS; MODELS, CARDIOVASCULAR; MUTATION; MYOCYTES, CARDIAC; RABBITS; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; TRPM CATION CHANNELS;

EID: 70349214859     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI40427     Document Type: Note

References (26)

1. Dessertenne, F. 1966. Ventricular tachycardia with 2 variable opposing foci. Arch. Mal. Coeur Vaiss. 59:263-272.
2. Roden, D.M., Woosley, R.L., and Primm, R.K. 1986. Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care. Am. Heart J. 111:1088-1093.
3. Sanguinetti, M.C., and Jurkiewicz, N.K. 1990. Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents. J. Gen. Physiol. 96:195-215.
4. Sanguinetti, M.C., and Jurkiewicz, N.K. 1992. Role of external Ca2+ and K+ in gating of cardiac delayed rectifier K+ currents. Pflugers Arch. 420:180-186.
5. Sanguinetti, M.C., et al. 1995. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell. 81:299-307.
6. Trudeau, M.C., et al. 1995. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 269:92-95.
7. Zhou, Z., et al. 1998. Electrophysiological and pharmacological properties of HERG channels in a stably transfected human cell line. Biophys. J. 74:230-241.
8. Smith, P.L., Baukrowitz, T., and Yellen, G. 1996. The inward rectification mechanism of the HERG cardiac potassium channel. Nature. 379:833-836. (Pubitemid 26067726)
9. Starkus, J.G., et al. 1997. Ion conduction through C-type inactivated Shaker channels. J. Gen. Physiol. 110:539-550.
10. Yang, T., Snyders, D.J., and Roden, D.M. 1997. Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells. Circ. Res. 80:782-789. (Pubitemid 27230052)
11. Vandenberg, J.I., et al. 2006. Temperature dependence of human ether-a-go-go-related gene K+ currents. Am. J. Physiol. Cell Physiol. 291:C165-C175.
12. Sale, H., et al. 2008. Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome. Circ. Res. 103:e81-e95.
13. Kr in rabbit hearts and of the HERG channel in human cell lines. J. Clin. Invest. 119:2745-2757.
14. McDonald, T.V., et al. 1997. A minK-HERG complex regulates the cardiac potassium current I(Kr). Nature. 388:289-292.
15. Abbott, G.W., et al. 1999. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell. 1999. 97:175-187. (Pubitemid 129746810)
16. Kratz, A., et al. 2004. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Laboratory reference values. N. Engl. J. Med. 351:1548-1563.
17. Garcia, E., et al. 2008. Profound hypokalemia: unusual presentation and management in a 12-year-old boy. Pediatr. Emerg. Care. 24:157-160.
18. Zhang, S. 2006. Isolation and characterization of I(Kr) in cardiac myocytes by Cs+ permeation. Am. J. Physiol. Heart Circ. Physiol. 290:H1038-H1049.
19. Doyle, D.A., et al. 1998. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science. 280:69-77.
20. Baukrowitz, T., and Yellen, G. 1996. Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a K+ channel. Science. 271:653-656. (Pubitemid 26052911)
21. Pardo, L.A., et al. 1992. Extracellular K+ specifically modulates a rat brain K+ channel. Proc. Natl. Acad. Sci. U. S. A. 89:2466-2470.
22. Jager, H., et al. 1998. Regulation of mammalian Shaker-related K+ channels: evidence for non-conducting closed and non-conducting inactivated states. J. Physiol. (Lond.). 506:291-301. (Pubitemid 28048360)
23. Loboda, A., Melishchuk, A., and Armstrong, C. 2001. Dilated and defunct K channels in the absence of K+. Biophys. J. 80:2704-2714.
24. Lopez-Barneo, J., et al. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
25. Kruse, M., et al. 2009. Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I. J. Clin. Invest. 119:2737-2744.
26. Guinamard, R., et al. 2006. Calcium-activated non-selective cation channels in mammalian cardiomyocytes. Trends Cardiovasc. Med. 16:245-250. (Pubitemid 44374369)