The cardiovascular and subjective effects of methamphetamine combined with γ-vinyl-γ-aminobutyric acid (GVG) in non-treatment seeking methamphetamine-dependent volunteers

Pharmacology Biochemistry and Behavior

Volumn 94, Issue 1, 2009, Pages 186-193

  De La Garza II, Richard ^b   Zorick, Todd ^a   Heinzerling, Keith G ^a   Nusinowitz, Steve ^c   London, Edythe D ^a   Shoptaw, Steven ^a   Moody, David E ^d   Newton, Thomas F ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c JULES STEIN EYE INSTITUTE   (United States)

^d UNIVERSITY OF UTAH   (United States)

Author keywords

Addiction; GVG; Methamphetamine

Indexed keywords

AMPHETAMINE; METHAMPHETAMINE; PLACEBO; VIGABATRIN;

ABDOMINAL CRAMP; ADULT; ANXIETY; ARM PAIN; ARTICLE; BLURRED VISION; CARDIOVASCULAR EFFECT; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG DEPENDENCE; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG ELIMINATION; DRUG ERUPTION; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DRUG USE; DYSPEPSIA; DYSPNEA; EVENING DOSAGE; FATIGUE; FEMALE; HEART RATE; HUMAN; HYPERTENSION; INDIGESTION; INGUINAL PAIN; INSOMNIA; MALE; MORNING DOSAGE; MYCOSIS; NAUSEA; NOSE DISEASE; OCULAR PRURITUS; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; REINFORCEMENT; SCORING SYSTEM; SEDATION; SHOULDER PAIN; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; TINEA PEDIS; TOOTH PAIN; VOLUNTEER;

4-AMINOBUTYRATE TRANSAMINASE; ADULT; AMPHETAMINE-RELATED DISORDERS; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM STIMULANTS; DEPRESSION; DOUBLE-BLIND METHOD; FEMALE; GABA AGENTS; HALF-LIFE; HEART RATE; HUMANS; MALE; METHAMPHETAMINE; MIDDLE AGED; REINFORCEMENT (PSYCHOLOGY); VIGABATRIN; VISUAL FIELDS;

EID: 70349205345     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.08.007     Document Type: Article

References (38)

1. Berger S.P., Winhusen T.M., Somoza E.C., Harrer J.M., Mezinskis J.P., Leiderman D.B., et al. A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence. Addiction 100 Suppl 1 (2005) 58-67
2. Bisaga A., Aharonovich E., Garawi F., Levin F.R., Rubin E., Raby W.N., et al. A randomized placebo-controlled trial of gabapentin for cocaine dependence. Drug Alcohol Depend 81 (2006) 267-274
3. Brodie J.D., Figueroa E., and Dewey S.L. Treating cocaine addiction: from preclinical to clinical trial experience with gamma-vinyl GABA. Synapse 50 (2003) 261-265
4. Brodie J.D., Figueroa E., Laska E.M., and Dewey S.L. Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction. Synapse 55 (2005) 122-125
5. Brodie JD, Case BG, Figueroa E, Dewey SL, Robinson JA, Wanderling JA, Laska EM. Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees. Am J Psychiatry in press, doi: 10.1176/appi.ajp.2009.08121811.
6. De La Garza R., Shoptaw S., and Newton T.F. Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteers. Int J Neuropsychopharmacol 11 (2008) 729-741
7. Dewey S.L., Morgan A.E., Ashby Jr. C.R., Horan B., Kushner S.A., Logan J., et al. A novel strategy for the treatment of cocaine addiction. Synapse 30 (1998) 119-129
8. Elkashef A.M., Rawson R.A., Anderson A.L., Li S.H., Holmes T., Smith E.V., et al. Bupropion for the treatment of methamphetamine dependence. Neuropsychopharmacology 33 (2008) 1162-1170
9. Fechtner R.D., Khouri A.S., Figueroa E., Ramirez M., Federico M., Dewey S.L., et al. Short-term treatment of cocaine and/or methamphetamine abuse with vigabatrin: ocular safety pilot results. Arch Ophthalmol 124 (2006) 1257-1262
10. Gerasimov M.R., Ashby Jr. C.R., Gardner E.L., Mills M.J., Brodie J.D., and Dewey S.L. Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse 34 (1999) 11-19
11. Gonzalez G., Desai R., Sofuoglu M., Poling J., Oliveto A., Gonsai K., et al. Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. Drug Alcohol Depend 87 (2007) 1-9
12. Haney M., Hart C., Collins E.D., and Foltin R.W. Smoked cocaine discrimination in humans: effects of gabapentin. Drug Alcohol Depend 80 (2005) 53-61
13. Haney M., Hart C.L., and Foltin R.W. Effects of baclofen on cocaine self-administration: opioid- and nonopioid-dependent volunteers. Neuropsychopharmacology 31 (2006) 1814-1821
14. Hart C.L., Ward A.S., Collins E.D., Haney M., and Foltin R.W. Gabapentin maintenance decreases smoked cocaine-related subjective effects, but not self-administration by humans. Drug Alcohol Depend 73 (2004) 279-287
15. Hart C.L., Haney M., Collins E.D., Rubin E., and Foltin R.W. Smoked cocaine self-administration by humans is not reduced by large gabapentin maintenance doses. Drug Alcohol Depend 86 (2007) 274-277
16. Hart C.L., Haney M., Vosburg S.K., Rubin E., and Foltin R.W. Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure. Behav Pharmacol 18 (2007) 71-75
17. Heinzerling K.G., Shoptaw S., Peck J.A., Yang X., Liu J., Roll J., et al. Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence. Drug Alcohol Depend 85 (2006) 177-184
18. Johnson B.A., Roache J.D., Ait-Daoud N., Wells L.T., Wallace C.L., Dawes M.A., et al. Effects of acute topiramate dosing on methamphetamine-induced subjective mood. Int J Neuropsychopharmacol 10 (2007) 85-98
19. Kampman K.M., Pettinati H., Lynch K.G., Dackis C., Sparkman T., Weigley C., et al. A pilot trial of topiramate for the treatment of cocaine dependence. Drug Alcohol Depend 75 (2004) 233-240
20. Kushner S.A., Dewey S.L., and Kornetsky C. The irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor gamma-vinyl-GABA blocks cocaine self-administration in rats. J Pharmacol Exp Ther 290 (1999) 797-802
21. Lile J.A., Stoops W.W., Allen T.S., Glaser P.E., Hays L.R., and Rush C.R. Baclofen does not alter the reinforcing, subject-rated or cardiovascular effects of intranasal cocaine in humans. Psychopharmacology 171 (2004) 441-449
22. Lile J.A., Stoops W.W., Glaser P.E., Hays L.R., and Rush C.R. Acute administration of the GABA reuptake inhibitor tiagabine does not alter the effects of oral cocaine in humans. Drug Alcohol Depend 76 (2004) 81-91
23. Molina P.E., Ahmed N., Ajmal M., Dewey S., Volkow N., Fowler J., et al. Co-administration of gamma-vinyl GABA and cocaine: preclinical assessment of safety. Life Sci 65 (1999) 1175-1182
24. Newton T.F., De La Garza II R., Kalechstein A.D., and Nestor L. Cocaine and methamphetamine produce different patterns of subjective and cardiovascular effects. Pharmacol Biochem Behav 82 (2005) 90-97
25. Newton T.F., Roache J.D., De La Garza II R., Fong T., Wallace C.L., Li S.H., et al. Bupropion reduces methamphetamine-induced subjective effects and cue-induced craving. Neuropsychopharmacology 31 (2006) 1537-1544
26. Newton T.F., Reid M.S., De La Garza II R., Mahoney J.J., Abad A., Condos R., et al. Evaluation of subjective effects of aripiprazole and methamphetamine in methamphetamine-dependent volunteers. Int J Neuropsychopharmacol 11 (2008) 1037-1045
27. Paul M., Dewey S.L., Gardner E.L., Brodie J.D., and Ashby Jr. C.R. Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats. Synapse 41 (2001) 219-220
28. Rotheram-Fuller E., De La Garza II R., Mahoney III J.J., Shoptaw S., and Newton T.F. Subjective and cardiovascular effects of cocaine during treatment with amantadine and baclofen in combination. Psychiatry Res 152 (2007) 205-210
29. Shoptaw S., Yang X., Rotheram-Fuller E.J., Hsieh Y.C., Kintaudi P.C., Charuvastra V.C., et al. Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine use. J Clin Psychiatry 64 (2003) 1440-1448
30. Shoptaw S., Heinzerling K.G., Rotheram-Fuller E., Steward T., Wang J., Swanson A.N., et al. Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence. Drug Alcohol Depend 96 (2008) 222-232
31. Sofuoglu M., Poling J., Mitchell E., and Kosten T.R. Tiagabine affects the subjective responses to cocaine in humans. Pharmacol Biochem Behav 82 (2005) 569-573
32. Streeter C.C., Hennen J., Ke Y., Jensen J.E., Sarid-Segal O., Nassar L.E., et al. Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment. Psychopharmacology 182 (2005) 516-526
33. Tsukamoto K., and Sved A.F. Contrasting effects of the GABA transaminase inhibitors gamma-vinylGABA and aminooxyacetic acid on arterial pressure following injection into nucleus tractus solitarius. Neuropharmacology 32 (1993) 575-579
34. Tsukamoto K., and Sved A.F. Enhanced gamma-aminobutyric acid-mediated responses in nucleus tractus solitarius of hypertensive rats. Hypertension 22 (1993) 819-825
35. Verhoeff N.P., Petroff O.A., Hyder F., Zoghbi S.S., Fujita M., Rajeevan N., et al. Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS. Epilepsia 40 10 (1999) 1433-1438
36. Weerts E.M., Froestl W., and Griffiths R.R. Effects of GABAergic modulators on food and cocaine self-administration in baboons. Drug Alcohol Depend 80 (2005) 369-376
37. Winhusen T.M., Somoza E.C., Harrer J.M., Mezinskis J.P., Montgomery M.A., Goldsmith R.J., et al. A placebo-controlled screening trial of tiagabine, sertraline and donepezil as cocaine dependence treatments. Addiction 100 Suppl 1 (2005) 68-77
38. Winhusen T., Somoza E., Ciraulo D.A., Harrer J.M., Goldsmith R.J., Grabowski J., et al. A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence. Drug Alcohol Depend 91 (2007) 141-148