α-tocopheryl succinate as a scaffold to develop potent inhibitors of breast cancer cell adhesion

Journal of Medicinal Chemistry

Volumn 52, Issue 18, 2009, Pages 5642-5648

  Wang, Dasheng ^a   Chuang, Hsiao Ching ^a   Weng, Shu Chuan ^a   Huang, Po Hsien ^a   Hsieh, Hao Yu ^a   Kulp, Samuel K ^a   Chen, Ching Shih ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[2 (4,8 DIMETHYLNON 1 ENYL) 2,5,7,8 TETRAMETHYLCHROMAN 6 YLOXY]ACETIC ACID; ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROL SUCCINATE; ANTIMETASTATIC AGENT; ANTINEOPLASTIC AGENT; F ACTIN; FOCAL ADHESION KINASE; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CELL MIGRATION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG TARGETING; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ALPHA-TOCOPHEROL; ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DRUG DISCOVERY; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INHIBITORY CONCENTRATION 50; MICE; NEOPLASM METASTASIS; PSEUDOPODIA;

EID: 70349194573     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9002457     Document Type: Article

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