MIB 1 immunostaining in cervical carcinoma of young patients

Gynecologic Oncology

Volumn 67, Issue 2, 1997, Pages 184-187

  Garzetti, G Gioele ^a   Ciavattini, Andrea ^a   Lucarini, Guendalina ^a   Goteri, Gaia ^a   De Nictolis, Michele ^a   Biagini, Graziella ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Age; Biologic aggressiveness; Cell proliferation; Cervical carcinoma; Cervix; Immunostaining; MIB 1; MIB 1 index; Prognosis

Indexed keywords

MONOCLONAL ANTIBODY KI 67;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER INVASION; CELL PROLIFERATION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TISSUE SECTION; UTERINE CERVIX CARCINOMA;

EID: 0031281544     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1997.4848     Document Type: Article

References (23)

1. Devesa S S, Young J L, Brinton L A, Fraumen J F. Recent trends in cervical uteri cancer. Cancer. 64:1989;2184-2190.
2. Free K, Roberts S, Bourne R, Dickie G, Ward B, Wright G, Hill B. Cancer of the cervix - Old and young, now and then. Gynecol Oncol. 43:1991;129-136.
3. Thomassen L V, Warshaw J, Lawhead R A, Unger E R. Invasive cervical cancer in young women. J Reprod Med. 37:1992;901-906.
4. Serur E, Fruchter R G, Maiman M, McGuire J, Arrastia C D, Gibbon D. Age, substance abuse, and survival of patients with cervical carcinoma. Cancer. 75:1995;2530-2538.
5. Saint Paul M T, Bremond A, Rochet Y. Cervical carcinoma before 35 years: epidemiologic and prognostic aspects. A retrospective study of 46 cases of cervix carcinoma before 35 years, of 449 new cases with carcinoma of cervix FIGO stage IA2-IV. J Gynecol Obstet Biol Reprod. 22:1993;737-742.
6. Pfeiffer D, Schubert Fritschle G, Meier W, Scheidel P, Hepp H. Age-dependent differences and changes in the clinical pattern and course of cervical carcinoma since 1973. Geburtshilfe Frauenheilkd. 52:1992;81-87.
7. Russell J M, Blair V, Hunter R D. Cervical carcinoma: prognosis in young patients. Br Med J. 295:1987;300-303.
8. Poka R, Juhansz B, Lampe L. Cervical cancer in young women: a poorer prognosis? Int J Gynecol Obstet. 46:1994;33-37.
9. Crowther M E. Is the nature of cervical carcinoma changing in young women? Obstet Gynecol Surv. 50:1995;71-82.
10. Gerdes J, Schwab U, Lemke H, Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer. 31:1983;13-20.
11. Grogan T M, Lippman S M, Spier C M, Slymen D J, Rybski J A, Rangel C S, Richter L C, Miller T P. Independent prognostic significance of a nuclear proliferation antigen in diffuse large cell lymphomas as determined by the monoclonal antibody Ki 67. Blood. 71:1988;1157-1160.
12. Hall P A, Richards M A, Gregory W M, d'Ardenne A J, Lister T A, Stansfeld A G. The prognostic value of Ki 67 immunostaining in non-Hodgkin's lymphoma. J Pathol. 154:1988;223-235.
13. Lelle R J, Heidenreich W, Stauch G, Gerdes J. The correlation of growth fractions with histologic grading and lymph node status in human mammary carcinoma. Cancer. 59:1987;83-88.
14. Weiss L M, Strickler J G, Medeiros L J, Gerdes J, Stein H, Warnke R A. Proliferative rates of non-Hodgkin's lymphomas as assessed by Ki 67 antibody. Hum Pathol. 18:1987;1155-1159.
15. Ueda T, Aozasa K, Tsujimoto M. Prognostic significance of Ki67 reactivity in soft tissue sarcoma. Cancer. 63:1989;1607-1611.
16. Robertson M J, Ritz J. Biology and clinical relevance of human natural killer cells. Blood. 12:1990;2421-2438.
17. Garzetti G G, Ciavattini A, Goteri G, De Nictolis M, Stramazzotti D, Lucarini G, Biagini G. Ki67 immunostaining (MIB 1 monoclonal antibody) in serous ovarian tumors: index of proliferative activity with prognostic significance. Gynecol Oncol. 56:1995;169-174.
18. Garzetti G G, Ciavattini A, Lucarini G, Goteri G, De Nictolis M, Muzzioli M, Fabris N, Romanini C, Biagini G. MIB 1 immunostaining in stage I squamous cervical carcinoma: relationship with natural killer cell activity. Gynecol Oncol. 58:1995;28-33.
19. Piver M S, Rutledge F, Smith J P. Five classes of extended hysterectomy for women with cervical cancer. Obstet Gynecol. 44:1974;265-272.
20. Smales E, Perry C M, Ashby M A, Baker J W. The influence of age on prognosis in carcinoma of the cervix. Br J Obstet Gynaecol. 94:1987;784-787.
21. Nakano T, Oka K. Differential value of Ki67 index and mitotic index of proliferating cell population: an assessment of cell cycle and prognosis in radiation therapy for cervical cancer. Cancer. 72:1993;2401-2408.
22. Oka K, Hoshi T, Arai T. Prognostic significance of the PC10 index as a prospective assay for cervical cancer treated with radiation therapy alone. Cancer. 70:1992;1545-1550.
23. Elliott P. Lymph node metastases, cell type, age, HPV status and type, neoadjuvant chemotherapy and treatment failures in cervical cancer. Int J Gynaecol Obstet. 49:1995;S17-S25.