AP-2α induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma

PLoS ONE

Volumn 4, Issue 9, 2009, Pages

  Bennett, Kristi L ^a   Romigh, Todd ^a   Eng, Charis ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2ALPHA; TRICHOSTATIN A; UNCLASSIFIED DRUG; HYDROXAMIC ACID; MICROSATELLITE DNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN SYNTHESIS INHIBITOR; PTEN PROTEIN, HUMAN;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA REPAIR; DOWN REGULATION; EPIGENETICS; GENE DISRUPTION; GENE EXPRESSION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; METHYLATION; MICROSATELLITE INSTABILITY; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; SQUAMOUS CELL CARCINOMA; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC EPIGENESIS; GENETICS; HEAD AND NECK TUMOR; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HEAD AND NECK NEOPLASMS; HUMANS; HYDROXAMIC ACIDS; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MODELS, BIOLOGICAL; PROTEIN SYNTHESIS INHIBITORS; PTEN PHOSPHOHYDROLASE; TRANSCRIPTION FACTOR AP-2;

EID: 70349139277     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006931     Document Type: Article

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