Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury

Cochrane Database of Systematic Reviews

Volumn , Issue 2, 2009, Pages

  Jones, Peter ^a   Dalziel, Stuart R ^b   Lamdin, Rain ^a   Miles, Jennifer ^a   Frampton, Christopher ^c  

^a AUCKLAND CITY HOSPITAL   (New Zealand)

^b STARSHIP CHILDREN S HOSPITAL   (New Zealand)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PLACEBO; TRAMADOL;

ACUTE KIDNEY FAILURE; ANALGESIA; BRONCHOSPASM; CARDIOTOXICITY; CLINICAL TRIAL; DRUG EFFECT; DRUG HYPERSENSITIVITY; GASTROINTESTINAL SYMPTOM; HEMATOLOGIC DISEASE; HUMAN; HYPERSENSITIVITY REACTION; INFORMATION PROCESSING; META ANALYSIS; MORTALITY; NEPHROTOXICITY; NEUROTOXICITY; PAIN; PHOTOSENSITIVITY DISORDER; RESPIRATION DEPRESSION; REVIEW; RISK ASSESSMENT; SENSITIVITY ANALYSIS; SKIN TOXICITY; SOFT TISSUE INJURY; SWELLING; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 70349131646     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD007789     Document Type: Review

References (117)

1. Accident Compensation Corporation (NZ). Managing Soft Tissue Ankle Injuries. http://www.acc.co.nz/PRD-EXT-CSMP/groups/external- providers/documents/internet/wcmz002487.pdf (accessed April 2008).
2. Almekinders LC, Gilbert JA. Healing of experimental muscle strains and the effects of nonsteroidal antiinflammatory medication. American Journal of Sports Medicine 1986;14(4):303-308
3. Almekinders LC, Baynes AJ, Bracey LW. An in vitro investigation into the effects of repetitive motion and nonsteroidal antiinflammatory medication on human tendon fibroblasts. American Journal of Sports Medicine 1995;23(1):119-123
4. Altman DG. Statistics inmedical journals: some recent trends. Statistics in Medicine 2000;19(23):3275-3289
5. Amadio P Jr, Cummings DM, Amadio PB. NSAIDs revisited: selection, monitoring, and safe use. Postgraduate Medicine 1997;101(2): 257-60, 63-7, 70-71
6. Andrade SE, Martinez C, Walker AM. Comparative safety evaluation of non-narcotic analgesics. Journal of Clinical Epidemiology 1998;51 (12):1357-1365 (Pubitemid 29009538)
7. Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine. Acute Pain Management: Scientific Evidence. www.anzca.edu.au/ resources/books-and-publications/acutepain.pdf (accessed April 2008).
8. Baldwin Lanier A. Use of nonsteroidal anti-inflammatory drugs following exercise-induced muscle injury. Sports Medicine 2003;33(3): 177-185 (Pubitemid 36433826)
9. Bandolier Extra. Combination Analgesics December 2005. http: //www.medicine.ox.ac.uk/bandolier/Extraforbando/combo.pdf (Accessed 31 July 2008).
10. Bandolier. Oxford league table of analgesics in acute pain. http: //www.jr2.ox.ac.uk/bandolier/booth/painpag/Acutrev/Analgesics/Leagtab.html (accessed 31 July 2008).
11. Barden J, Edwards JE, Mason L, McQuay HJ, Moore RA. Outcomes in acute pain trials: systematic review of what was reported?. Pain 2004;109(3):351-356 (Pubitemid 38638712)
12. Bergh I, Sjostrom B, Oden A, Steen B. Assessing pain and pain relief in geriatric patients with non-pathological fractures with different rating scales. Aging-Clinical & Experimental Research 2001;13(5): 355-361 (Pubitemid 34023885)
13. Bijur PE, Latimer CT, Gallagher EJ. Validation of a verbally administered numerical rating scale of acute pain for use in the emergency department. Academic Emergency Medicine 2003;10(4):390-392
14. Bogatov VB, Weinhold P, Dahners LE. The influence of a cyclooxygenase- 1 inhibitor on injured and uninjured ligaments in the rat. American Journal of Sports Medicine 2003;31(4):574-576 (Pubitemid 36875390)
15. Bollini P, Garcia Rodriguez LA, Perez Gutthann S, Walker AM. The impact of research quality and study design on epidemiologic estimates of the effect of nonsteroidal anti-inflammatory drugs on upper gastrointestinal tract disease. Archives of Internal Medicine 1992;152 (6):1289-1295
16. Brooks PM, Day RO. Nonsteroidal antiinflammatory drugs - differences and similarities. New England Journal of Medicine 1991;324 (24):1716-1725
17. Browning CH. Nonsteroidal anti-inflammatory drugs and severe psychiatric side effects. International Journal of Psychiatry in Medicine 1996;26(1):25-34. (Pubitemid 26137131)
18. Burke A, Smyth EM, Fitzgerald GA. Analgesic-Antipyretic Agents. In: Brunton LL, Lazo JS, Parker KL editor(s). Goodman and Gilman's The Pharmaceutical Basis of Therapeutics. NY: McGraw-Hill, 2006: 671-716.
19. Cassell EP, Finch CF, Stathakis VZ. Epidemiology of medically treated sport and active recreation injuries in the Latrobe Valley, Victoria, Australia. British Journal of Sports Medicine 2003;37(5):405-409
20. Chan FK. Primer: managing NSAID-induced ulcer complications- -balancing gastrointestinal and cardiovascular risks. Nature Clinical Practice Gastroenterology & Hepatology 2006;3(10):563-573
21. Cochrane Collaboration open learning material for reviewers Version 1.1. Summary Statistics for Dichotomous Outcome Data. www.cochrane-net.org/ openlearning/HTML/modA1-5.htm (accessed April 2008).
22. Centre for Reviews and Dissemination. Treatment modalities for soft tissue injuries of the ankle: a critical review (structured abstract). http: //www.mrw.interscience.wiley.com/cochrane/cldare/articles/DARE- 951779/frame.html 1997.
23. Cukiernik VA, Lim R, Warren D, Seabrook JA, Matsui D, Rieder MJ. Naproxen versus acetaminophen for therapy of soft tissue injuries to the ankle in children. Annals of Pharmacotherapy 2007;41(9):1368-1374 (Pubitemid 47311356)
24. Dalton JD Jr, Schweinle JE. Randomized controlled noninferiority trial to compare extended release acetaminophen and ibuprofen for the treatment of ankle sprains. Annals of Emergency Medicine 2006; 48(5):615-623
25. de Gara C, Taylor M, Hedges A. Assessment of analgesic drugs in soft tissue injuries presenting to an accident and emergency department - a comparison of antrafenine, paracetamol and placebo. Postgraduate Medical Journal 1982;58(682):489-492
26. Deeks J, Altman DG. Chapter 16: Effect Measure for Meta-analysis of trial with binary outcomes. In: Egger M, Smith GD, Altman DG editor(s). Systematic Reviews. 2nd Edition. London: BMJ, 2001: 313-315
27. Deeks JJ. Issues in the selection of a summary statistic for metaanalysis of clinical trials with binary outcomes. Statistics in Medicine 2002;21(11):1575-1600
28. Deeks JJ, Higgins JPT, Altman DG (editors). In: Higgins JPT, Green S (editors). Analysing data and undertaking meta-analyses. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 [updated September 2008]; Chapter 9.5.2. www.cochranehandbook. org (accessed September 2008).
29. Dexter F, Chestnut DH. Analysis of statistical tests to compare visual analog scale measurements among groups. Anesthesiology 1995;82 (4):896-902.
30. Diaz JA, Cuervo C, Valderrama AM, Kohles J. Valdecoxib provides effective pain relief following acute ankle sprain. Journal of International Medical Research 2006;34(5):456-467 (Pubitemid 44756132)
31. Egger M, Dickersin K, Davey-Smith G. Chapter 3: Problems and limitations in conducting systematic reviews. In: Egger M, Smith GD, Altman DG editor(s). Systematic reviews in healthcare: Meta-analysis in context. 2nd Edition. London: BMJ, 2001:43-65.
32. Egger M, Smith GD. Chapter 2: Principles and procedures for systematic reviews. In: Egger M, Smith GD, Altman DG editor(s). Systematic reviews in healthcare: Meta-analysis in context. London: BMJ, 2001:23-42.
33. Ekman EF, Fiechtner JJ, Levy S, Fort JG. Efficacy of celecoxib versus ibuprofen in the treatment of acute pain: a multicenter, double-blind, randomized controlled trial in acute ankle sprain. American Journal of Orthopedics 2002;31(8):445-451
34. Ekman EF, Ruoff G, Kuehl K, Ralph L, Hormbrey P, Fiechtner J, et al. The COX-2 specific inhibitor Valdecoxib versus tramadol in acute ankle sprain: a multicenter randomized, controlled trial. American Journal of Sports Medicine 2006;34(6):945-955 (Pubitemid 43725761)
35. Falgarone G, Zerkak D, Bauer C, Messow M, Dougados M. How to define a Minimal Clinically Individual State (MCIS) with pain VAS in daily practice for patients suffering from musculoskeletal disorders. Clinical and Experimental Rheumatology 2005;23(2):235-238 (Pubitemid 40663006)
36. Farkouh ME, Kirshner H, Harrington RA, Ruland S, Verheugt FW, Schnitzer TJ, et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial. Lancet 2004;364(9435):675-684 (Pubitemid 39140623)
37. Farrar JT, Berlin JA, Strom BL. Clinically important changes in acute pain outcome measures: a validation study. Journal of Pain and Symptom Management 2003;25(5):406-411
38. Feldman HI, Kinman JL, Berlin JA, Hennessy S, Kimmel SE, Farrar J, et al. Parenteral ketorolac: the risk for acute renal failure. Annals of Internal Medicine 1997;126(3):193-199 (Pubitemid 27061572)
39. Fosnocht DE, Chapman CR, Swanson ER, Donaldson GW. Correlation of change in visual analog scale with pain relief in the ED. American Journal of Emergency Medicine 2005;23(1):55-59
40. Gallagher EJ, Liebman M, Bijur PE. Prospective validation of clinically important changes in pain severity measured on a visual analog scale. Annals of Emergency Medicine 2001;38(6):633-638 (Pubitemid 33131561)
41. Gallagher EJ, Bijur PE, Latimer C, Silver W. Reliability and validity of a visual analog scale for acute abdominal pain in the ED. American Journal of Emergency Medicine 2002;20(4):287-290 (Pubitemid 34701069)
42. Garcia Rodriguez LA, Perez Gutthann S, Walker AM, Lueck L. The role of non-steroidal anti-inflammatory drugs in acute liver injury. BMJ 1992;305(6858):865-868
43. Geraci M, Bottai M. Quantile regression for longitudinal data using the asymmetric Laplace distribution. Biostatistics 2007;8(1):140-154 (Pubitemid 44906108)
44. Glasziou PP, Sanders SL. Investigating causes of heterogeneity in systematic reviews. Statistics in Medicine 2002;21(11):1503-1511
45. Gotzsche PC. Non-steroidal anti-inflammatory drugs. BMJ 2000; 320(7241):1058-1061
46. Gutstein HB, Akil H. Opioid Analgesics. In: Brunton LL, Lazo JS, Parker KL editor(s). Goodman and Gilman's The Pharmaceutical Basis of Therapeutics. New York: McGraw-Hill, 2006:547-590
47. Handoll HHG, Gillespie WJ, Gillespie LD, Madhok R. Moving towards evidence-based healthcare for musculoskeletal injuries: featuring the work of the Cochrane Bone, Joint and Muscle Trauma Group. Journal of the Royal Society of Health 2007;127(4):168-173 (Pubitemid 47009438)
48. Henry D. Assessing the benefits and risks of drugs. The example of NSAIDs. Australian Family Physician 1990;19(3):378-83, 385, 387.
49. Herbison P. personal communication 2008.
50. Hertel J. The role of nonsteroidal anti-inflammatory drugs in the treatment of acute soft tissue injuries. Journal of Athletic Training 1997;32(4):350-358 (Pubitemid 127530242)
51. Hewitt DJ, Todd KH, Xiang J, Jordan DM, Rosenthal NR. Tramadol/ acetaminophen or hydrocodone/acetaminophen for the treatment of ankle sprain: a randomized, placebo-controlled trial. Annals of Emergency Medicine 2007;49(4):468-480, 480 e1-2. (Pubitemid 46413423)
52. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557-560
53. Higgins JPT, Altman DG, editors. Assessing risk of bias in included studies. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008]; Chapter 8. http: //www.cochrane-handbook.org/ (accessed 31 July 2008).
54. Higgins JPT, Deeks JJ, Altman DG, editors. In Higgins JPT, Green S, editors. Special topics in statistics. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008]; Chapter 16. http://www.cochrane-handbook.org/ (accessed 31 July 2008).
55. Sterne JAC, Egger M, Moher D, editors. In: Higgins JPT, Green S, editors. Addressing reporting biases. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 [updated February 2008]; Chapter 10. http://www.cochrane-handbook.org/ (accessed 31 July 2008).
56. Honig S. Clinical trials in acute musculoskeletal injury states. An analysis of methodology. American Journal of Medicine 1988;84(5A): 42-44 (Pubitemid 18147739)
57. International Association for the Study of Pain. IASP Pain Terminology. http://www.iasppain. org/AM/Template.cfm?Section=General-Resource- Links&Template=/CM/HTMLDisplay.cfm&ContentID=3058#Painz (accessed 31 July 2008).
58. Ivins D. Acute ankle sprain: an update. American Family Physician 2006;74(10):1714-1720
59. Jensen MP, Martin SA, Cheung R. The meaning of pain relief in a clinical trial. Journal of Pain 2005;6(6):400-406 (Pubitemid 40804345)
60. Johnson GR, Wen SF. Syndrome of flank pain and acute renal failure after binge drinking and nonsteroidal anti-inflammatory drug ingestion. Journal of the American Society of Nephrology 1995;5(9): 1647-1652
61. Jones P. NSAIDs in soft tissue injury: current practice vs. available evidence. Annual Scientific Meeting of the Australasian College for Emergency Medicine; Gold Coast, Australia. 1998.
62. Jones P. Analgesia in soft-tissue injury: current practice in Auckland is not supported by the available evidence. New Zealand Medical Journal 1999;112(1097):376-379 (Pubitemid 29484719)
63. Kaufman HL, Fischer AH, Carroll M, Becker JM. Colonic ulceration associated with nonsteroidal anti-inflammatory drugs. Report of three cases. Diseases of the Colon and Rectum 1996;39(6):705-710 (Pubitemid 26181144)
64. Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrono C. Do selective cyclo-oxygenase-2 inhibitors and traditional nonsteroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ 2006;332(7553):1302-1308 (Pubitemid 44365384)
65. Kellett J. Acute soft tissue injuries - a review of the literature. Medicine and Science in Sports and Exercise 1986;18(5):489-500. (Pubitemid 17203394)
66. Kelly AM. Does the clinically significant difference in visual analog scale pain scores vary with gender, age, or cause of pain?. Academic Emergency Medicine 1998;5(11):1086-1090
67. Kelly AM. The minimum clinically significant difference in visual analogue scale pain score does not differ with severity of pain. Emergency Medicine Journal 2001;18(3):205-207 (Pubitemid 34070897)
68. Kirkwood BR, Sterne JAC. Medical Statistics. 2nd Edition. Oxford: Blackwell, 2003:43.
69. Lee JS, Hobden E, Stiell IG, Wells GA. Clinically important change in the visual analog scale after adequate pain control. Academic Emergency Medicine 2003;10(10):1128-1130 (Pubitemid 37205689)
70. Lefebvre C, Manheimer E, Glanville J, editors. In: Higgins JPT, Green S, editors. Searching for studies. Cochrane Handbook for Systematic Reviews of Interventions 5.0.1 [updated September 2008]; Chapter 6. www.cochrane-handbook. org (accessed September 2008).
71. Lund I, Lundeberg T, Sandberg L, Budh CN, Kowalski J, Svensson E. Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups. BioMed Central Medical Research Methodology 2005;5:31. (Pubitemid 41584035)
72. Major P. Should non-steroidal anti-inflammatory agents be used in acute soft tissue injuries? [Bor ikke-steroide antiinflammatoriske midler brukes ved akutte blotdelsskader?]. Tidsskrift for Den Norske Lægeforening 1992;112(12):1614-1615
73. Manterola C, Astudillo P, Losada H, Pineda V, Sanhueza A, Vial M. Analgesia in patients with acute abdominal pain. Cochrane Database of Systematic Reviews 2007, Issue 3. [DOI: 10.1002/14651858.CD005660.pub2] (Pubitemid 351805424)
74. Martin DJ, Shea P. Soft tissue pain and physical therapy. Anaesthesia and Intensive Care Medicine 2005;6(1):23-25
75. McClellan CM, Greenwood R, Benger JR. Effect of an extended scope physiotherapy service on patient satisfaction and the outcome of soft tissue injuries in an adult emergency department. Emergency Medicine Journal 2006;23(5):384-387 (Pubitemid 44295296)
76. McNicol ED, Strassels S, Goudas L, Lau J, Carr DB. NSAIDS or paracetamol, alone or combined with opioids, for cancer pain. Cochrane Database of Systematic Reviews 2005, Issue 2. [DOI: 10.1002/14651858.CD005180]
77. Medibank Private. Safe Sports Report 2006. http: //www.medibank.com.au/ Client/Documents/Pdfs/Medi- Safe-Sports-Report-2006.pdf (accessed 31 July 2008). [: http: //www.medibank.com.au/Client/Documents/Pdfs/Medi-Safe- Sports-Report-2006.pdf ]
78. Mehallo CJ, Drezner JA, Bytomski JR. Practical management: nonsteroidal antiinflammatory drug (NSAID) use in athletic injuries. Clinical Journal of Sports Medicine 2006;16(2):170-174
79. Merry AF, Webster CS, Holland RL, Middleton NG, Schug SA, James M, et al. Clinical tolerability of perioperative tenoxicamin 1001 patients - a prospective, controlled, double-blind, multi-centre study. Pain 2004;111(3):313-322 (Pubitemid 39201153)
80. Moore A, McQuay H, Gavaghan D. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics. Pain 1996;66(2-3):229-237 (Pubitemid 26283992)
81. Moore A, Moore O, McQuay H, Gavaghan D. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: use of pain intensity and visual analogue scales. Pain 1997;69(3):311-315 (Pubitemid 27096413)
82. Moore RA, Edwards JE, McQuay HJ. Acute pain: individual patient meta-analysis shows the impact of different ways of analysing and presenting results. Pain 2005;116(3):322-331
83. Moore A, Oxford Pain Research Group. Personal communication September 2007.
84. Motola D, Vaccheri A, Silvani MC, Poluzzi E, Bottoni A, De Ponti F, et al. Pattern of NSAID use in the Italian general population: a questionnaire-based survey. European Journal of Clinical Pharmacology 2004;60(10):731-738
85. Myles PS, Troedel S, Boquest M, Reeves M. The pain visual analog scale: Is it linear or nonlinear?. Anesthesia and Analgesia 1999;89(6): 1517-1520
86. Myles PS, Urquhart N. The linearity of the visual analogue scale in patients with severe acute pain. Anaesthesia and Intensive Care 2005; 33(1):54-58 (Pubitemid 40287596)
87. Nadarajah A, Abrahan L, Lau FL, Hwang LJ, Fakir-Bolte C. Efficacy and tolerability of celecoxib compared with diclofenac slow release in the treatment of acute ankle sprain in an Asian population. Singapore Medical Journal 2006;47(6):534-542 (Pubitemid 43900502)
88. Nicholl JP, Coleman P, Williams BT. The epidemiology of sports and exercise related injury in the United Kingdom. British Journal of Sports Medicine 1995;29(4):232-238 (Pubitemid 26020504)
89. Obremsky WT, Seaber AV, Ribbeck BM, Garrett WE Jr. Biomechanical and histologic assessment of a controlled muscle strain injury treated with piroxicam. American Journal of Sports Medicine 1994; 22(4):558-561
90. Ogilvie-Harris DJ, Gilbart M. Treatment modalities for soft tissue injuries of the ankle: a critical review. Clinical Journal of Sports Medicine 1995;5(3):175-186
91. Paoloni JA, Orchard JW. The use of therapeutic medications for softtissue injuries in sports medicine. Medical Journal of Australia 2005; 183(7):384-388
92. Partsch G, Schwarzer C, Eberl R. The effects of ibuprofen and diclofenac on the chemotaxis and adenosine triphosphate level of polymorphonuclear cells in vitro. Journal of Rheumatology 1990;17(5): 583-588 (Pubitemid 20201731)
93. Perez Gutthann S, Garcia Rodriguez LA, Raiford DS, Duque Oliart A, Ris Romeu J. Nonsteroidal anti-inflammatory drugs and the risk of hospitalization for acute renal failure. Archives of Internal Medicine 1996;156(21):2433-2439 (Pubitemid 26391472)
94. Petrella R, Ekman EF, Schuller R, Fort JG. Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial. Clinical Journal of Sports Medicine 2004;14(4):225-231 (Pubitemid 38989679)
95. Philip BK. Parametric statistics for evaluation of the visual analog scale. Anesthesia and Analgesia 1990;71(6):710.
96. Powell CV, Kelly AM, Williams A. Determining the minimum clinically significant difference in visual analog pain score for children. Annals of Emergency Medicine 2001;37(1):28-31. (Pubitemid 32066336)
97. Quiding H, Haggquist SO. Visual analogue scale and the analysis of analgesic action. European Journal of Clinical Pharmacology 1983;24 (4):475-478
98. Rahusen FT, Weinhold PS, Almekinders LC. Nonsteroidal anti-in- flammatory drugs and acetaminophen in the treatment of an acute muscle injury. American Journal of Sports Medicine 2004;32(8): 1856-1859
99. Rietveld JA, Pilmore HL, Jones PG, Theis JC, Bowie DA, Dempster AG, et al. Necrotising fasciitis: a single centre's experience. New Zealand Medical Journal 1995;108(995):72-74
100. Rosen DA, Morris JL, Rosen KR, Valenzuela RC, Vidulich MG, Steelman RJ, et al. Analgesia for pediatric thoracostomy tube removal. Anesthesia and Analgesia 2000;90(5):1025-1028
101. Salo D, Eget D, Lavery RF, Garner L, Bernstein S, Tandon K. Can patients accurately read a visual analog pain scale?. American Journal of Emergency Medicine 2003;21(7):515-519 (Pubitemid 37494037)
102. Schneider S, Seither B, Tonges S, Schmitt H. Sports injuries: population based representative data on incidence, diagnosis, sequelae, and high risk groups. British Journal of Sports Medicine 2006;40(4): 334-339
103. Schnitzer TJ, Burmester GR, Mysler E, Hochberg MC, Doherty M, Ehrsam E, et al. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial. Lancet 2004;364(9435):665-674 (Pubitemid 39140622)
104. Seedat YK, Aboo N, Naicker S, Parsoo I. Acute renal failure in the "Comrades Marathon" runners. Renal Failure 1989-1990;11(4): 209-212
105. Singh G, Ramey DR, Morfeld D, Shi H, Hatoum HT, Fries JF. Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study. Archives of Internal Medicine 1996;156(14):1530-1536 (Pubitemid 126751973)
106. Svensson E. Concordance between ratings using different scales for the same variable. Statistics in Medicine 2000;19(24):3483-3496 (Pubitemid 32056698)
107. Szczeklik A. Adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs. Annals of Allergy 1987;59(5 Pt 2):113-118 (Pubitemid 18006573)
108. Todd PA, Sorkin EM. Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 1988;35(3):244-285
109. Vitting KE, Nichols NJ, Seligson GR. Naproxen and acute renal failure in a runner. Annals of Internal Medicine 1986;105(1):144. (Pubitemid 16097953)
110. Walker RJ, Fawcett JP, Flannery EM, Gerrard DF. Indomethacin potentiates exercise-induced reduction in renal hemodynamics in athletes. Medicine & Science in Sports & Exercise 1994;26(11):1302-1306
111. Warner DC, Schnepf G, Barrett MS, Dian D, Swigonski NL. Prevalence, attitudes, and behaviors related to the use of nonsteroidal antiinflammatory drugs (NSAIDs) in student athletes. Journal of Adolescent Health 2002;30(3):150-153 (Pubitemid 34175138)
112. Weiler JM. Medical modifiers of sports injury. The use of nonsteroidal anti-inflammatory drugs (NSAIDs) in sports soft-tissue injury. Clinics in Sports Medicine 1992;11(3):625-644
113. Wiffen PJ, McQuay HJ, Moore RA. Carbamazepine for acute and chronic pain. Cochrane Database of Systematic Reviews 2005, Issue 3. [DOI: 10.1002/14651858.CD005451]
114. Williams GJP, Sperryn PN. Sports Medicine. Arnold, 1981.
115. Williams ACdC, Davies HT, Chadury Y. Simple pain rating scales hide complex idiosyncratic meanings. Pain 2000;85(3):457-463 (Pubitemid 30214173)
116. Wright V. Historical overview of non-steroidal anti-inflammatory drugs. British Journal of Rheumatology 1995;34 Suppl 1:2-4.
117. Yates DW, Laing GS, Peters K, Kumar K. Mild analgesics and the accident and emergency department - cost and safetymore important than potency?. Archives of Emergency Medicine 1984;1(4):197-203. (Pubitemid 15166395)