Cerebrospinal fluid monoamine metabolites and suicide

Nordic Journal of Psychiatry

Volumn 63, Issue 4, 2009, Pages 276-279

  Jokinen, Jussi ^a   Nordström, Anna Lena ^a   Nordström, Peter ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Biomarkers; CSF 5 HIAA; CSF HVA; Depression; Intent; Serotonin; Suicide; Violent method

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; HOMOVANILLIC ACID;

ADULT; ARTICLE; BECK SUICIDE INTENT SCALE; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FATALITY; HUMAN; LETHALITY; MALE; RATING SCALE; SUICIDAL BEHAVIOR; VIOLENCE;

ADULT; AGGRESSION; DEPRESSIVE DISORDER; HOMOVANILLIC ACID; HUMANS; HYDROXYINDOLEACETIC ACID; INTENTION; MALE; MIDDLE AGED; PERSONALITY INVENTORY; PSYCHOMETRICS; RISK ASSESSMENT; STATISTICS AS TOPIC; SUICIDE; SUICIDE, ATTEMPTED; VIOLENCE; YOUNG ADULT;

EID: 70349111852     PISSN: 08039488     EISSN: 15024725     Source Type: Journal    
DOI: 10.1080/08039480802571077     Document Type: Article

References (27)

1. Mann JJ. Neurobiology of suicidal behaviour. Nat Rev Neurosci 2003;4:819-28.
2. Sher L, Mann JJ. Neurobiology of suicide. In: Soares JC, Gershon S, editors. Textbook of medical psychiatry. New York: Marcel Dekker; 2003. p. 701-11.
3. Samuelsson M, Jokinen J, Nordström A-L, Nordström P. CSF 5-HIAA, suicide intent and hopelessness in the prediction of early suicide in male high-risk suicide attempters. Acta Psychiatr Scand 2006;113:44-7.
4. Åsberg M, Träskman L, Thorén P. 5-HIAA in the cerebrospinal fluid: A biological suicide predictor? Arch Gen Psychiatry 1976;33: 1193-7.
5. Mann JJ, Currier D. A review of prospective studies of biologic predictors of suicidal behavior in mood disorders. Arch of Suicide Res 2007;11:3-16.
6. Sher L, Mann JJ, Träskman-Bendz L, Huang Y, Fertuck EA, Stanley BH. Lower cerebrospinal fluid homovanillic acid levels in depressed suicide attempters. J Affect Disord 2006;90:83-9.
7. Sher L. Cerebrospinal fluid monoamine metabolites and suicide. Nord J Psychiatry 2007;61:233-4.
8. Träskman L, Asberg M, Bertilsson L, Sjostrand L. Monoamine metabolites in CSF and suicidal behavior. Arch Gen Psychiatry 1981;38:631-6.
9. Engström G, Alling C, Blennow K, Regnell G, Träskman-Bendz L. Reduced cerebrospinal HVA concentrations and HVA5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls. Eur Neuropsychopharmacol 1999;9: 399-405.
10. Roy A, Agren H, Pickar D, Linnoila M, Doran AR, Cutler NR et al. Reduced CSF concentrations of homovanillic acid and homovanillic acid to 5-hydroxyindoleacetic acid ratios in depressed patients: Relationship to suicidal behavior and dexamethasone nonsuppression. Am J Psychiatry 1986;143:1539-45.
11. Roy A, De Jong J, Linnoila M. Cerebrospinal fluid monoamine metabolites and suicidal behavior in depressed patients. A 5-year follow-up study. Arch Gen Psychiatry 1989;46:609-12.
12. Sher L, Carballo JJ, Grunebaum MF, Burke AK, Zalsman G, Huang YY, et al. A prospective study of the association of cerebrospinal fluid monoamine metabolite levels with lethality of suicide attempts in patients with bipolar disorder. Bipolar Disord 2006;8:543-50.
13. Beck AT, Schuyler D, Herman I. Development of suicidal intent scales, in the prediction of suicide. In: Beck AT, Resnik HL, Lettieri DJ, editors. The prediction of suicide. Bowie, MD: Charles Press; 1974. p. 45-56.
14. Suominen K, Isometsä E, Ostamo A, Lönnqvist J. Level of suicidal intent predicts overall mortality and suicide after attempted suicide: A 12-year follow-up study. BMC Psychiatry 2004;4:11.
15. Placidi GP, Oquendo MA, Malone KM, Huang YY, Ellis SP, Mann JJ. Aggressivity, suicide attempts, and depression: Relationship to cerebrospinal fluid monoamine metabolite levels. Biol Psychiatry 2001;50:783-91.
16. Agren H. Life at risk: Markers of suicidality in depression. Psychiatr Dev 1983;1:87-103.
17. Mann JJ, Malone KM, Sweeney JA, Brown RP, Linnoila M, Stanley B, et al. Attempted suicide characteristics and cerebrospinal fluid amine metabolites in depressed inpatients. Neuropsychopharmacology 1996;15:576-86.
18. Träskman L, Asberg M, Bertilsson L, Sjostrand L. Monoamine metabolites in CSF and suicidal behaviour. Arch Gen Psychiatry 1981;38:631-6.
19. Beck AT, Beck R, KovacsM. Classification of suicidal behaviors: I. Quantifying intent and medical lethality. Am J Psychiatry 1975; 132:285-7.
20. Bertilsson L. Quantitative mass fragmentography - A valuable tool in clinical pharmacology. In: Usdin E, editor. Clinical pharmacology in psychiatry. New York: Elsevier; 1981. p. 59-72.
21. Reddy PL, Khanna S, Subhash MN, Channabasavanna SM, Rao BS. CSF amine metabolites in depression. Biol. Psychiatry 1992;31: 112-8.
22. Geracioti TDJr, Keck PEJr, Ekhator NN, West SA, Baker DG, Hill KK, et al. Continuous covariability of dopamine and serotonin metabolites in human cerebrospinal fluid. Biol Psychiatry 1998;44:228-33.
23. Cremniter D, Jamain S, Kollenbach K, et al. CSF 5-HIAA levels are lower in impulsive as compared to nonimpulsive violent suicide attempters and control subjects. Biol Psychiatry 1999;45:1572-9.
24. Virkkunen M, Eggert M, Rawlings R, Linnoila M. A prospective follow-up study of alcoholic violent offenders and fire setters. Arch Gen Psychiatry 1996;53:523-9.
25. Kapur S, Mann JJ. Role of the dopaminergic system in depression. Biol Psychiatry 1992;32:1-17.
26. Jokinen J, Nordström A-L, Nordström P. The relationship between CSF HVA5-HIAA ratio and suicide intent in suicide attempters. Arch Suicide Res 2007;11:187-92.
27. Oquendo MA, Currier D, Mann JJ. Prospective studies of suicidal behavior in major depressive and bipolar disorders: What is the evidence for predictive risk factors? Acta Psychiatr Scand 2006; 114:151-8.