Effect of PEGylation of N-WASP181-200 on the inhibitory potency for renal aminoglycoside accumulation

Bioconjugate Chemistry

Volumn 20, Issue 8, 2009, Pages 1553-1558

  Fujii, Kenji ^a   Nagai, Junya ^a   Sawada, Takeshi ^a   Yumoto, Ryoko ^a   Takano, Mikihisa ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ASPARAGINYLISOLEUCYLSERYLHISTIDYLTHREONYLLYSYLGLUTAMYLLYSYLLY SYLLYSYLGLYCYLLYSYLALANYLLYSYLLYSYLLYSYLARGINYLLEUCYLTHREONYLLYSINE; GENTAMICIN; HABEKACIN; MACROGOL; N WASP 181 200; PEGASPARAGINYLISOLEUCYLSERYLHISTIDYLTHREONYLLYSYLGLUTAMYLLY SYLLYSYLLYSYLGLYCYLLYSYLALANYLLYSYLLYSYLLYSYLARGINYLLEUCYLTHREONYLLYSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRUSH BORDER; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; DRUG BINDING; DRUG INHIBITION; DRUG POTENCY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PLASMA HALF LIFE; RAT; SUSPENSION;

RATTUS;

ANIMALS; ANTI-BACTERIAL AGENTS; DIBEKACIN; GENTAMICINS; KIDNEY; MALE; MICE; MICE, INBRED STRAINS; PEPTIDE FRAGMENTS; POLYETHYLENE GLYCOLS; PROTEIN CONFORMATION; RATS; RATS, WISTAR; WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL;

EID: 70349111106     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc900094g     Document Type: Article

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