Influences of dosage regimen and co-administration of low-molecular weight proteins and basic peptides on renal accumulation of arbekacin in mice

Journal of Antimicrobial Chemotherapy

Volumn 61, Issue 3, 2008, Pages 658-664

  Murakami, Sachiko ^a   Nagai, Junya ^a   Fujii, Kenji ^a   Yumoto, Ryoko ^a   Takano, Mikihisa ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Aminoglycoside; Megalin; Nephrotoxicity; Once daily dosing; Renal uptake kinetics

Indexed keywords

CYTOCHROME C; DEXTRO AMINO ACID; FOSFOMYCIN; HABEKACIN; LYSOZYME; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN[181-200]; PSSM 8; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BOLUS INJECTION; CARBOXY TERMINAL SEQUENCE; COMBINATION CHEMOTHERAPY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG DOSE REGIMEN; DRUG HALF LIFE; DRUG INHIBITION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; KIDNEY TUBULE ABSORPTION; MALE; MONOTHERAPY; MOUSE; NEPHROTOXICITY; NONHUMAN; SINGLE DRUG DOSE; TISSUE DISTRIBUTION;

AMINOGLYCOSIDES; ANIMALS; DIBEKACIN; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; MALE; MICE; MOLECULAR WEIGHT; PEPTIDES; PROTEINS;

EID: 40049095303     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm512     Document Type: Article

References (29)