Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver

Drug Metabolism and Disposition

Volumn 37, Issue 9, 2009, Pages 1916-1921

  Jin, Kyung Lee ^a   Abe, Koji ^a   Bridges, Arlene S ^a   Patel, Nita J ^b   Raub, Thomas J ^b   Pollack, Gary M ^a   Brouwer, Kim L R ^a  

^a University of North Carolina   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 4; PARACETAMOL; PARACETAMOL GLUCURONIDE; PARACETAMOL SULFATE;

ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DRUG DISPOSITION; DRUG EXCRETION; FEMALE; HEPATOBILIARY SYSTEM; HYPOTHESIS; LIVER PERFUSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; WILD TYPE;

ACETAMINOPHEN; ALGORITHMS; ANALGESICS, NON-NARCOTIC; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE; BLOTTING, WESTERN; BODY WEIGHT; FEMALE; GLUCURONIDES; LIVER; MALE; MICE; MICE, INBRED C57BL; ORGAN SIZE; PERFUSION; SEX CHARACTERISTICS; SULFATES;

MUS;

EID: 70349110162     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.026815     Document Type: Article

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