Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase

Journal of the American Chemical Society

Volumn 131, Issue 36, 2009, Pages 12866-12867

  Lu, Changyuan ^a   Lin, Yu ^a   Yeh, Syun Ru ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION MECHANISMS; ANTI-TUMORS; BINDING MOLECULES; CHEMOTHERAPEUTIC AGENTS; DIOXYGENASES; DRUG TARGETS; IMMUNOSUPPRESSIVE FUNCTION; INHIBITORY SUBSTRATES; L-TRYPTOPHAN; MITOMYCIN C; RATE DETERMINING STEP; RE-EVALUATION;

AMINO ACIDS; BINDING ENERGY; ETHANOL; PORPHYRINS; SUBSTRATES;

BINDING SITES;

3 INDOLE ETHANOL; INDOLE DERIVATIVE; INDOLEAMINE 2,3 DIOXYGENASE; MITOMYCIN C; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; ISOMER; MICHAELIS CONSTANT; MICHAELIS MENTEN KINETICS; STEREOCHEMISTRY;

BINDING SITES; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INDOLES; MITOMYCIN; MOLECULAR STRUCTURE; PROTEIN BINDING; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EID: 70349084620     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9029768     Document Type: Article

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