-
1
-
-
0033576675
-
More than one way to die: Apoptosis, necrosis and reactive oxygen damage
-
W. Fiers, R. Beyaert, W. Declercq, P.Vandenabeele, More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 18, 7719-7730 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
2
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Y. Shi, J. E. Evans, K. L. Rock, Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425, 516-521 (2003).
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
3
-
-
0035575679
-
Programmed cell death: Alive and well in the new millennium
-
S. H. Kaufmann, M. O. Hengartner, Programmed cell death: Alive and well in the new millennium. Trends Cell Biol. 11, 526-534 (2001).
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 526-534
-
-
Kaufmann, S.H.1
Hengartner, M.O.2
-
4
-
-
54249096028
-
Caspases in apoptosis and beyond
-
J. Li, J. Yuan, Caspases in apoptosis and beyond. Oncogene 27, 6194-6206 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 6194-6206
-
-
Li, J.1
Yuan, J.2
-
5
-
-
58149464289
-
The Jekyll and Hyde functions of caspases
-
C. H. Yi, J. Yuan, The Jekyll and Hyde functions of caspases.Dev. Cell 16, 21-34 (2009).
-
(2009)
Dev. Cell
, vol.16
, pp. 21-34
-
-
Yi, C.H.1
Yuan, J.2
-
7
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
T. Burckstummer, C. Baumann, S. Blüml, E. Dixit, G. Dürnberger, H. Jahn, M. Planyavsky, M. Bilban, J. Colinge, K. L. Bennett, G. Superti-Furga, An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat. Immunol. 10, 266-272 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Blüml, S.3
Dixit, E.4
Dürnberger, G.5
Jahn, H.6
Planyavsky, M.7
Bilban, M.8
Colinge, J.9
Bennett, K.L.10
Superti-Furga, G.11
-
8
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
T. Fernandes-Alnemri, J. W. Yu, P. Datta, J. Wu, E. S. Alnemri, AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458, 509-513 (2009).
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
9
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
V. Hornung, A. Ablasser, M. Charrel-Dennis, F. Bauernfeind, G. Horvath, D. R. Caffrey, E. Latz, K. A. Fitzgerald, AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458, 514-518 (2009).
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
10
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
T. L. Roberts, A. Idris, J. A. Dunn, G. M. Kelly, C. M. Burnton, S. Hodgson, L. L. Hardy, V. Garceau, M. J. Sweet, I. L. Ross, HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA.Science 323, 1057-1060 (2009).
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
Hardy, L.L.7
Garceau, V.8
Sweet, M.J.9
Ross, I.L.10
-
11
-
-
62449317819
-
Cell death in the skin
-
S. Lippens, E. Hoste, P. Vandenabeele, P. Agostinis, W. Declercq, Cell death in the skin. Apoptosis 14, 549-569 (2009).
-
(2009)
Apoptosis
, vol.14
, pp. 549-569
-
-
Lippens, S.1
Hoste, E.2
Vandenabeele, P.3
Agostinis, P.4
Declercq, W.5
-
12
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
P. Li, H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman, J. Salfeld, E. Towne, D. Tracey, S.Wardwell, F.-Y.Wei, W. Wong, R. Kamen, T. Seshadri, Mice deficient in IL-1β- converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80, 401-411 (1995).
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
Towne, E.11
Tracey, D.12
Wardwell, S.13
Wei, F.-Y.14
Wong, W.15
Kamen, R.16
Seshadri, T.17
-
13
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
S.Wang, M. Miura, Y. K. Jung, H. Zhu, E. Li, Y.Yuan, Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92, 501-509 (1998).
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, Y.6
-
14
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin- 1β by keratinocytes
-
L. Feldmeyer, M. Keller, G. Niklaus, D. Hohl, S. Werner, H. D. Beer, The inflammasome mediates UVB-induced activation and secretion of interleukin- 1β by keratinocytes. Curr. Biol. 17, 1140-1145 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
Hohl, D.4
Werner, S.5
Beer, H.D.6
-
15
-
-
34447570932
-
Caspase-14 protects against epidermal UVB photodamage and water loss
-
G. Denecker, E. Hoste, B. Gilbert, T. Hochepied, P. Ovaere, S. Lippens, C. Van den Broecke, P. Van Damme, K. D'Herde, J. P. Hachem, G. Borgonie, R. B. Presland, L. Schoonjans, C. Libert, J. Vandekerckhove, K. Gevaert, P. Vandenabeele, W. Declercq, Caspase-14 protects against epidermal UVB photodamage and water loss. Nat. Cell Biol. 9, 666-674 (2007).
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 666-674
-
-
Denecker, G.1
Hoste, E.2
Gilbert, B.3
Hochepied, T.4
Ovaere, P.5
Lippens, S.6
Van Den Broecke, C.7
Van Damme, P.8
D'herde, K.9
Hachem, J.P.10
Borgonie, G.11
Presland, R.B.12
Schoonjans, L.13
Libert, C.14
Vandekerckhove, J.15
Gevaert, K.16
Vandenabeele, P.17
Declercq, W.18
-
16
-
-
39049098268
-
Caspase-14 reveals its secrets
-
G. Denecker, P. Ovaere, P. Vandenabeele, W. Declercq, Caspase-14 reveals its secrets. J. Cell Biol. 180, 451-458 (2008).
-
(2008)
J. Cell Biol.
, vol.180
, pp. 451-458
-
-
Denecker, G.1
Ovaere, P.2
Vandenabeele, P.3
Declercq, W.4
-
17
-
-
33846922252
-
Caspase-8 prevents sustained activation of NF-κB in monocytes undergoing macrophagic differentiation
-
C. Rébé, S. Cathelin, S. Launay, R. Filomenko, L. Prétovat, C. L'Ollivier, E. Gyan, O. Micheau, S. Grant, A. Dubart-Kupperschmitt, M. Fontenay, E. Solary, Caspase-8 prevents sustained activation of NF-κB in monocytes undergoing macrophagic differentiation. Blood 109, 1442-1450 (2007).
-
(2007)
Blood
, vol.109
, pp. 1442-1450
-
-
Rébé, C.1
Cathelin, S.2
Launay, S.3
Filomenko, R.4
Prétovat, L.5
L'ollivier, C.6
Gyan, E.7
Micheau, O.8
Grant, S.9
Dubart-Kupperschmitt, A.10
Fontenay, M.11
Solary, E.12
-
18
-
-
20044368626
-
Requirement for caspase-8 in NF-κB activation by antigen receptor
-
H. Su, N. Bidère, L. Zheng, A. Cubre, K. Sakai, J. Dale, L. Salmena, R. Hakem, S. Straus, M. Lenardo, Requirement for caspase-8 in NF-κB activation by antigen receptor. Science 307, 1465-1468 (2005).
-
(2005)
Science
, vol.307
, pp. 1465-1468
-
-
Su, H.1
Bidère, N.2
Zheng, L.3
Cubre, A.4
Sakai, K.5
Dale, J.6
Salmena, L.7
Hakem, R.8
Straus, S.9
Lenardo, M.10
-
19
-
-
63649143438
-
Dynamic expression of epidermal caspase 8 simulates a wound healing response
-
P. Lee, D. J. Lee, C. Chan, S.W. Chen, I. Ch'en, C. Jamora, Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 458, 519-523 (2009).
-
(2009)
Nature
, vol.458
, pp. 519-523
-
-
Lee, P.1
Lee, D.J.2
Chan, C.3
Chen, S.W.4
Ch'en, I.5
Jamora, C.6
-
20
-
-
0035956432
-
Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation
-
M. Chidgey, C. Brakebusch, E. Gustafsson, A. Cruchley, C. Hail, S. Kirk, A. Merritt, A. North, C. Tselepis, J. Hewitt, C. Byrne, R. Fassler, D. Garrod, Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation. J. Cell Biol. 155, 821-832 (2001).
-
(2001)
J. Cell Biol.
, vol.155
, pp. 821-832
-
-
Chidgey, M.1
Brakebusch, C.2
Gustafsson, E.3
Cruchley, A.4
Hail, C.5
Kirk, S.6
Merritt, A.7
North, A.8
Tselepis, C.9
Hewitt, J.10
Byrne, C.11
Fassler, R.12
Garrod, D.13
-
22
-
-
58849089529
-
Mechanisms of regulated unconventional protein secretion
-
W. Nickel, C. Rabouille, Mechanisms of regulated unconventional protein secretion. Nat. Rev. Mol. Cell Biol. 10, 148-155 (2009).
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 148-155
-
-
Nickel, W.1
Rabouille, C.2
-
23
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
M. Keller, A. Ruegg, S. Werner, H. D. Beer, Active caspase-1 is a regulator of unconventional protein secretion. Cell 132, 818-831 (2008).
-
(2008)
Cell
, vol.132
, pp. 818-831
-
-
Keller, M.1
Ruegg, A.2
Werner, S.3
Beer, H.D.4
-
24
-
-
37849013277
-
Sunburned skin activates inflammasomes
-
B. Faustin, J. C. Reed, Sunburned skin activates inflammasomes.Trends Cell Biol. 18, 4-8 (2008).
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 4-8
-
-
Faustin, B.1
Reed, J.C.2
-
25
-
-
0035312832
-
Paracrine regulation of keratinocyte proliferation and differentiation
-
S. Werner, H. Smola, Paracrine regulation of keratinocyte proliferation and differentiation. Trends Cell Biol. 11, 143-146 (2001).
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 143-146
-
-
Werner, S.1
Smola, H.2
-
26
-
-
56049124633
-
Inflammasomes and inflammatory caspases in skin inflammation
-
L. Iversen, C. Johansen, Inflammasomes and inflammatory caspases in skin inflammation. Expert Rev. Mol. Diagn. 8, 697-705 (2008).
-
(2008)
Expert Rev. Mol. Diagn.
, vol.8
, pp. 697-705
-
-
Iversen, L.1
Johansen, C.2
-
27
-
-
3342980733
-
Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation
-
C. A. Dinarello, Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation. Curr. Opin. Pharmacol. 4, 378-385 (2004).
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 378-385
-
-
Dinarello, C.A.1
-
28
-
-
58049194057
-
Rilonacept in cryopyrin- associated periodic syndromes: The beginning of longer-acting interleukin-1 antagonism
-
L. D. Church, M. F. McDermott, Rilonacept in cryopyrin- associated periodic syndromes: The beginning of longer-acting interleukin-1 antagonism. Nat. Clin. Pract. Rheumatol. 5, 14-15 (2009).
-
(2009)
Nat. Clin. Pract. Rheumatol.
, vol.5
, pp. 14-15
-
-
Church, L.D.1
McDermott, M.F.2
-
29
-
-
66049094734
-
In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes
-
10.1084/jem.20082481
-
H. J. Lachmann, P. Lowe, S. D. Felix, C. Rordorf, K. Leslie, S. Madhoo, H. Wittkowski, S. Bek, N. Hartmann, S. Bosset, P. N. Hawkins, T. Jung., In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes. J. Exp. Med. 10.1084/jem.20082481 (2009).
-
(2009)
J. Exp. Med.
-
-
Lachmann, H.J.1
Lowe, P.2
Felix, S.D.3
Rordorf, C.4
Leslie, K.5
Madhoo, S.6
Wittkowski, H.7
Bek, S.8
Hartmann, N.9
Bosset, S.10
Hawkins, P.N.11
Jung, T.12
-
30
-
-
0034661657
-
Skin-specific caspase-1- transgenic mice show cutaneous apoptosis and pre-endotoxin shock condition with a high serum level of IL-18
-
K. Yamanaka, M. Tanaka, H. Tsutsui, T. S. Kupper, K. Asahi, H. Okamura, K. Nakanishi, M. Suzuki, N. Kayagaki, R. A. Black, D. K. Miller, K. Nakashima, M. Shimizu, H. Mizutani, Skin-specific caspase-1- transgenic mice show cutaneous apoptosis and pre-endotoxin shock condition with a high serum level of IL-18. J. Immunol. 165, 997-1003 (2000).
-
(2000)
J. Immunol.
, vol.165
, pp. 997-1003
-
-
Yamanaka, K.1
Tanaka, M.2
Tsutsui, H.3
Kupper, T.S.4
Asahi, K.5
Okamura, H.6
Nakanishi, K.7
Suzuki, M.8
Kayagaki, N.9
Black, R.A.10
Miller, D.K.11
Nakashima, K.12
Shimizu, M.13
Mizutani, H.14
-
31
-
-
0030016946
-
Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes: Evidence that IL-1- inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease
-
R. W. Groves, T. Rauschmayr, K. Nakamura, S. Sarkar, I. R. Williams, T. S. Kupper, Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes: Evidence that IL-1- inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease. J. Clin. Invest. 98, 336-344 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 336-344
-
-
Groves, R.W.1
Rauschmayr, T.2
Nakamura, K.3
Sarkar, S.4
Williams, I.R.5
Kupper, T.S.6
-
32
-
-
47949099098
-
Origin and physiological roles of inflammation
-
R. Medzhitov, Origin and physiological roles of inflammation. Nature 454, 428-435 (2008).
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
33
-
-
77953676706
-
-
We thank S.Werner (ETH Zurich) for critically reading the manuscript. This work was supported by the Swiss National Science Foundation (grant 3100A0- 104170 to H.-D.B.) and by the ETH Zurich. G.S. is a member of the Zurich graduate program in Molecular Life Science
-
We thank S.Werner (ETH Zurich) for critically reading the manuscript. This work was supported by the Swiss National Science Foundation (grant 3100A0- 104170 to H.-D.B.) and by the ETH Zurich. G.S. is a member of the Zurich graduate program in Molecular Life Science.
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