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Volumn 33, Issue 12, 2009, Pages 1581-1583

How do JAK2-inhibitors work in myelofibrosis: An alternative hypothesis

Author keywords

Cytokine; JAK2; JAK2 inhibitor; Myelofibrosis

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; ITF 2357; JANUS KINASE 2 INHIBITOR; JANUS KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 70249107079     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.06.001     Document Type: Note
Times cited : (17)

References (10)
  • 1
    • 67549114832 scopus 로고    scopus 로고
    • Hypothesis: how do jak2-inhibitors work in myelofibrosis
    • Mesa R., and Gale R.P. Hypothesis: how do jak2-inhibitors work in myelofibrosis. Leuk Res 33 (2009) 1156-1157
    • (2009) Leuk Res , vol.33 , pp. 1156-1157
    • Mesa, R.1    Gale, R.P.2
  • 2
    • 38349053791 scopus 로고    scopus 로고
    • Jak2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials
    • Pardanani A. Jak2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials. Leukemia 22 (2008) 23-30
    • (2008) Leukemia , vol.22 , pp. 23-30
    • Pardanani, A.1
  • 3
    • 62949167301 scopus 로고    scopus 로고
    • A phase i study of TG101348, an orally bioavailable JAK-selective inhibitor, in patients with myelofibrosis
    • Pardanani A., GotlIb J., Jamieson C., Cortes J., Talpaz M., and Stone R.M. A phase i study of TG101348, an orally bioavailable JAK-selective inhibitor, in patients with myelofibrosis. Blood 112 (2008) 97A
    • (2008) Blood , vol.112
    • Pardanani, A.1    GotlIb, J.2    Jamieson, C.3    Cortes, J.4    Talpaz, M.5    Stone, R.M.6
  • 4
    • 62949201160 scopus 로고    scopus 로고
    • The JAK inhibitor, INCB018424, demonstrates durable and marked clinical responses in primary myelofibrosis and post-polycythemia/essential thrombocythemia myelofibrosis
    • Verdstovsek S., Kantarjian H.M., Pardanani A.D., Thomas D., Cortes J., and Mesa R.A. The JAK inhibitor, INCB018424, demonstrates durable and marked clinical responses in primary myelofibrosis and post-polycythemia/essential thrombocythemia myelofibrosis. Blood (2008) 1762A
    • (2008) Blood
    • Verdstovsek, S.1    Kantarjian, H.M.2    Pardanani, A.D.3    Thomas, D.4    Cortes, J.5    Mesa, R.A.6
  • 5
    • 23044445190 scopus 로고    scopus 로고
    • Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease
    • Vannucchi A.M., Migliaccio A.R., Paoletti F., Chagraoui H., and Wendling F. Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease. Semin Oncol 32 (2005) 365-372
    • (2005) Semin Oncol , vol.32 , pp. 365-372
    • Vannucchi, A.M.1    Migliaccio, A.R.2    Paoletti, F.3    Chagraoui, H.4    Wendling, F.5
  • 6
    • 54049138867 scopus 로고    scopus 로고
    • Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence
    • Lataillade J.J., Pierre-Louis O., Hasselbalch H.C., Uzan G., Jasmin C., and Martyre M.C. Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence. Blood 112 (2008) 3026-3035
    • (2008) Blood , vol.112 , pp. 3026-3035
    • Lataillade, J.J.1    Pierre-Louis, O.2    Hasselbalch, H.C.3    Uzan, G.4    Jasmin, C.5    Martyre, M.C.6
  • 7
    • 57649137956 scopus 로고    scopus 로고
    • Leptin stimulates both JAK2_dependent and JAK2-independent signaling pathways
    • Jiang L., Li Z., and Rui L. Leptin stimulates both JAK2_dependent and JAK2-independent signaling pathways. J Biol Chem (2008)
    • (2008) J Biol Chem
    • Jiang, L.1    Li, Z.2    Rui, L.3
  • 8
    • 52949089050 scopus 로고    scopus 로고
    • Jaks in pathology: role of janus kinases in hematopoietic malignancies and immunodeficiencies
    • Vainchenker W., Dusa A., and Constantinescu S.N. Jaks in pathology: role of janus kinases in hematopoietic malignancies and immunodeficiencies. Semin Cell Dev Biol 19 (2008) 385-393
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 385-393
    • Vainchenker, W.1    Dusa, A.2    Constantinescu, S.N.3
  • 9
    • 67549145773 scopus 로고    scopus 로고
    • A phase 2a study of the histone-deacetylase inhibitor ITF2357 in patients with JAK2V617F positive chronic myeloproliferative neoplasms
    • Rambaldi A., Dellacasa C.M., Salmoiraghi S., Spinelli O., Ferrari M.L., and Gattoni E. A phase 2a study of the histone-deacetylase inhibitor ITF2357 in patients with JAK2V617F positive chronic myeloproliferative neoplasms. Blood 112 (2008) 100A
    • (2008) Blood , vol.112
    • Rambaldi, A.1    Dellacasa, C.M.2    Salmoiraghi, S.3    Spinelli, O.4    Ferrari, M.L.5    Gattoni, E.6
  • 10
    • 42349087790 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor ITF 2357 selectively targets cells bearing mutated JAK2(V617F)
    • Guerini V., Barbui V., Spinelli O., Salvi A., Dellacasa C., and Carobbio A. The histone deacetylase inhibitor ITF 2357 selectively targets cells bearing mutated JAK2(V617F). Leukemia 22 (2008) 740-747
    • (2008) Leukemia , vol.22 , pp. 740-747
    • Guerini, V.1    Barbui, V.2    Spinelli, O.3    Salvi, A.4    Dellacasa, C.5    Carobbio, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.