PKCθ and Itk functionally interact during primary mouse CD3+ T cell activation

Immunology Letters

Volumn 126, Issue 1-2, 2009, Pages 54-59

  Thuille, Nikolaus ^a   Lutz Nicoladoni, Christina ^a   Letschka, Thomas ^a   Hermann Kleiter, Natascha ^a   Heit, Isabelle ^b   Baier, Gottfried ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b Nycomed GmbH   (Germany)

Author keywords

Gene ablation; Itk; Pharmacological inhibition; PKC ; T cells

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE T CELL KINASE; PROTEIN KINASE C THETA; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; CD3 ANTIGEN; CD69 ANTIGEN; EMT PROTEIN TYROSINE KINASE; EMT PROTEIN-TYROSINE KINASE; HERMES ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; ISOENZYME; LEUKOCYTE ANTIGEN; PRKCQ PROTEIN, MOUSE; PROTEIN KINASE C; T LYMPHOCYTE ANTIGEN;

ANIMAL CELL; ARTICLE; CD3+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; EX VIVO STUDY; KNOCKOUT MOUSE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSACTIVATION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; FEMALE; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENETICS; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PROTEIN BINDING; T LYMPHOCYTE; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD3; ANTIGENS, CD44; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BLOTTING, WESTERN; CELL PROLIFERATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FLOW CYTOMETRY; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; ISOENZYMES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 70249102435     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.07.014     Document Type: Article

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