Odoroside A and ouabain inhibit Na+/K+-ATPase and prevent NF-κB-inducible protein expression by blocking Na+-dependent amino acid transport

Biochemical Pharmacology

Volumn 78, Issue 9, 2009, Pages 1157-1166

  Takada, Yohei ^a   Matsuo, Kentaro ^b   Ogura, Hirotsugu ^a   Bai, Liming ^c,d   Toki, Asami ^c   Wang, Liyan ^c   Ando, Masayoshi ^c   Kataoka, Takao ^a,b  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d QIQIHAR UNIVERSITY   (China)

Author keywords

Amino acid transport; ICAM 1; Na+ K+ ATPase; NF B; Odoroside A; Ouabain

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CARDENOLIDE; CYTOKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; MESSENGER RNA; ODOROSIDE A; OUABAIN; SODIUM ION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ARTICLE; CARCINOMA CELL; CELL NUCLEUS; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RNA TRANSLATION;

AMINO ACIDS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARDENOLIDES; CELL LINE, TUMOR; DNA PRIMERS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; NF-KAPPA B; OUABAIN; POLYMERASE CHAIN REACTION; PROTEINS; RNA, MESSENGER; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70249093581     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.06.027     Document Type: Article

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