Anti-inflammatory activity and possible mechanism of extract from Mikania laevigata in carrageenan-induced peritonitis

Journal of Pharmacy and Pharmacology

Volumn 61, Issue 8, 2009, Pages 1097-1104

  Alves, Claudiney F ^a   Alves, Vanessa B F ^a   De Assis, Izabel P ^a   Clemente Napimoga, Juliana T ^a   Uber Bucek, Elizabeth ^a   Dal Secco, Daniela ^b   Cunha, Fernando Q ^b   Rehder, Vera L G ^c   Napimoga, Marcelo H ^a  

^a UNIVERSITY OF UBERABA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Coumarin; Inflammation; Mikania laevigata; Neutrophil

Indexed keywords

AMINOGUANIDINE; ANTIINFLAMMATORY AGENT; CARRAGEENAN; COUMARIN; INTERLEUKIN 1BETA; MIKANIA LAEVIGATA EXTRACT; NITRIC OXIDE; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; COUMARIN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG MECHANISM; HARVEST PERIOD; LEUKOCYTE ADHERENCE; MALE; MASS FRAGMENTOGRAPHY; MIKANIA; MIKANIA LAEVIGATA; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PLANT LEAF; ANIMAL; BRAZIL; CELL MOTION; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; ISOLATION AND PURIFICATION; LEUKOCYTE ROLLING; METABOLISM; PATHOPHYSIOLOGY; SEASON; TRADITIONAL MEDICINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAZIL; CARRAGEENAN; CELL MOVEMENT; COUMARINS; DISEASE MODELS, ANIMAL; LEUKOCYTE ROLLING; MALE; MEDICINE, TRADITIONAL; MICE; MIKANIA; NEUTROPHILS; NITRIC OXIDE; PERITONITIS; PLANT EXTRACTS; PLANT LEAVES; SEASONS;

EID: 70249089082     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/61.08.0014     Document Type: Article

References (32)

1. Malech HL, Gallin JI. Current concepts: immunology. Neutrophils in human diseases. N Engl J Med 1987; 317: 687-694.
2. Jones AK et al. In vivo leukocyte migration in arthritis. Arthritis Rheum 1991; 34: 270-275.
3. Luster AD et al. Immune cell migration in inflammation: present and future therapeutic targets. Nature Immunol 2005; 6: 1182-1190.
4. Kasama T et al. Neutrophil derived cytokines: potential therapeutic targets in inflammation. Curr Drug Targets Inflamm Allergy 2005; 4: 273-279.
5. Palmer G et al. Leukocyte migration to rheumatoid joints: enzymes take over. Arthritis Rheum 2006; 54: 2707-2710.
6. Cattani F et al. The role of CXCR2 activity in the contact hypersensitivity response in mice. Eur Cytokine Netw 2006; 17: 42-48.
7. Kim ND et al. A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis. J Exp Med 2006; 203: 829-835.
8. Napimoga MH et al. Lonchocarpus sericeus lectin decreases leukocyte migration and mechanical hypernociception by inhibiting cytokine and chemokines production. Int Immunopharmacol 2007; 7: 824-835.
9. Dal Secco D et al. Nitric oxide inhibits neutrophil migration by a mechanism dependent on ICAM-1: role of soluble guanylate cyclase. Nitric Oxide 2006; 15: 77-86.
10. Kubes P et al. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88: 4651-4655.
11. Kubes P, Granger DN. Nitric oxide modulates vascular permeability. Am J Physiol Heart Circ Physiol 1992; 262: H611-H615.
12. Laszlo F et al. Association of microvascular leakage with induction of nitric oxide synthase: effects of nitric oxide synthase inhibitors in various organs. Eur J Pharmacol 1995; 283: 47-53.
13. Oliveira F et al. Morfodiagnose das folhas e das partes reprodutivas de Mikania laevigata Schultz Bip ex Baker. Rev Bras Farmacognosia 1986; 1: 20-34.
14. Bighetti AE et al. Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz. Phytomedicine 2005; 12: 72-77.
15. Davino SC et al. Antimicrobial activity of kaurenoic acid derivatives substituted on carbon-15. Braz J Med Biol Res 1989; 22: 1127-1129.
16. Yatsuda R et al. Effects of Mikania genus plants on growth and cell adherence of mutans streptococci. J Ethnopharmacol 2005; 97: 183-189.
17. Leite MGR et al. Estudo farmacologico comparativo de Mikania glomerata Spreng (guaco) Justicia pectoralis Jacq (anador) e Torresea cearensis Fr. All (cumarú). Rev Bras Farm 1993; 74: 12-15.
18. Suyenaga ES et al. Antiinflammatory investigation of some species of Mikania. Phytother Res 2002; 16: 519-523.
19. de Carvalho Osorio A, Martins JLS. Determination of coumarin in fluid extract and tincture of 'guaco' by first derivative spectrophotometry. Rev Bras Cienc Farmac 2004; 40: 481-486.
20. Tavares-Murta BM et al. Failure of neutrophil chemotactic function in septic patients. Crit Care Med 2002; 30: 1056-1061.
21. Green LC et al. Nitrate biosynthesis in man. Proc Natl Acad Sci USA 1981; 78: 7764-7768.
22. Thurston G et al. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 2000; 6: 460-463.
23. Baez S. Simultaneous measurements of radii and wall thickness of microvessels in the anesthetized rat. Circ Res 1969; 25: 315-329.
24. Fortes ZB et al. Direct vital microscopic study of defective leukocyte-endothelial interaction in diabetes mellitus. Diabetes 1991; 40: 1267-1273.
25. Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod 2007; 70: 461-477.
26. Calixto JB et al. Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor kappa B (NF-kappaB). Planta Med 2003; 69: 973-983.
27. dos Santos SC et al. LC characterisation of guaco medicinal extracts, Mikania laevigata and M. glomerata, and their effects on allergic pneumonitis. Planta Med 2006; 72: 679-684.
28. Silva MGV et al. Chemical variation during daytime of constituents of the essential oil Ocimum gratissimum leaves. Fitoterapia 1999; 70: 32-34.
29. Muller WA. Migration of leukocytes across endothelial junctions: some concepts and controversies. Microcirculation 2001; 8: 181-193.
30. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340: 115-126.
31. Alderton WK et al. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001; 357: 593-615.
32. Davis KL et al. Novel effects of nitric oxide. Annu Rev Pharmacol Toxicol 2001; 41: 203-236.