Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 34, 2009, Pages 14333-14338

  Hilge, Mark ^a   Aelen, Jan ^a   Foarce, Alice ^a   Perrakis, Anastassis ^b   Vuister, Geerten W ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Alternative splicing; Ca 2+ sensor; Ca2+ binding domain; Homeostasis

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN; ISOPROTEIN; SLC8A2 PROTEIN, MOUSE; SLC8A3 PROTEIN, MOUSE; SODIUM; SODIUM CALCIUM EXCHANGER 1; SODIUM-CALCIUM EXCHANGER 1;

ARTICLE; BINDING SITE; CALCIUM BINDING; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONFORMATIONAL TRANSITION; CYTOPLASM; ELECTRICITY; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DOG; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STATIC ELECTRICITY; THERMODYNAMICS;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCIUM; CRYSTALLOGRAPHY, X-RAY; DOGS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM; SODIUM-CALCIUM EXCHANGER; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 70149116358     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902171106     Document Type: Article

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