Telomere attrition and telomerase activity are associated with GSTM1 polymorphism in oral cancer

Cancer Biomarkers

Volumn 5, Issue 4-5, 2009, Pages 189-195

  Sainger, Rachana N ^a,c   Shah, Franky D ^a   Telang, Shaila D ^b   Shah, Pankaj M ^a   Patel, Prabhudas S ^a  

^a GUJARAT CANCER AND RESEARCH INSTITUTE   (India)

^b M S UNIVERSITY OF BARODA   (India)

^c ENH Research Institute   (United States)

Author keywords

GSTM1 polymorphism; Oral cancer; Telomerase activity; Telomere attrition

Indexed keywords

GLUTATHIONE TRANSFERASE M1; TELOMERASE;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER STAGING; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CHROMOSOME SIZE; CLINICAL FEATURE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOUTH CANCER; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING HABIT; TELOMERE; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ADULT; AGED; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; POLYMORPHISM, GENETIC; TELOMERASE; TELOMERE;

EID: 70149099374     PISSN: 15740153     EISSN: None     Source Type: Journal    
DOI: 10.3233/CBM-2009-0103     Document Type: Article

References (34)

1. C. Borras, J.M. Esteve, J.R. Vin, J Sastre, J. Vin and F.V. Pallardo, Glutathione Regulates Telomerase Activity in 3T3 Fibroblasts, J Biol Chem 279 (2004), 34332-34335.
2. E.S. Epel, E.H. Blackburn, J. Lin, F.S. Dhabhar, N.E. Adler, J.D. Morrow and R.M. Cawthon, Accelerated telomere shortening in response to life stress, Proc Natl Acad Sci U S A 101 (2004), 17323-17324.
3. R. Gertler, R. Rosenberg, D. Stricker, J. Friederichs, A. Hoos, M.Werner, K. Ulm, B. Holzmann, H. Nekarda and J.R. Siewert, Telomere Length and Human Telomerase Reverse Transcriptase expression as markers for progression and prognosis of colorectal carcinoma, J Clin Oncol 22 (2004), 1807-1814.
4. M.M. Menon and M.R. Simha, Telomerase and telomere length in normal and malignant human endometrium as prognostic markers, Indian J Pathol Microbiol 46 (2003), 394-398.
5. R.R. Plentz, M. Caselitz, J.S. Bleck, M. Gebel, P. Flemming, S. Kubicka, M.P. Manns and K.L. Rudolph, Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma, Hepatology 40 (2004), 80-86.
6. D.M. Parkin, F. Bray and P. Pisani, Global Cancer Statistics, 2002, CA Cancer J Clin 55 (2005), 74-108.
7. I.C. Paterson J.W. Eveson and S. Prime, Molecular changes in oral cancer may reflect aetiology and ethinic origin, Eur J Cancer 32 (1996), 150-153.
8. D. Saranath, Integrated Biology and Molecular Pathology of Oral Cancer, In: Contemporary issues in oral cancer. Oxford University Press New Delhi, 1999.
9. U. Nair, H. Bartsch and J. Nair, Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: A review of agents and causative mechanisms, Mutagenesis 19 (2004), 251-262.
10. B.P. Patel, U.M. Rawal, P.M. Shah, J.A. Prajapati, R.M. Rawal, T.K. Dave and P.S. Patel, Study of tobacco habits and enzymatic antioxidant system in oral cancer, Oncology 68 (2005), 511-519.
11. U.J. Nair, J. Nair, B. Mathew and H. Bartsch, Glutathione S transferase M1 and T1 null genotypes as risk factors for oral leukoplakia in ethnic Indian betel quid/tobacco chewers, Carcinogenesis 20 (1999), 743-748.
12. S.C Buch, P.N. Notani and R.A. Bhisey, Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population, Carcinogenesis 23 (2002), 803-807.
13. N.W. Kim, M.A. Piatyszek, K.R. Prowse, C.B. Harley, M.D. West, P.L. Ho, G.M. Coviello, W.E. Wright, S.L.Weinrich and J.W. Shay, Specific association of human telomerase activity with immortal cells and cancer, Science 266 (1994), 2011-2015.
14. C.B. Harley, A.B. Futcher and C.W. Greider, Telomeres shorten during ageing of human fibroblasts, Nature 345 (1990), 458-460.
15. G. Sashida, J.H. Ohyashiki, A. Nakajima, M. Sumi, K. Kawakubo, T. Tauchi and K. Ohyashiki, Telomere dynamics in myelodysplastic syndrome determined by telomere measurement of marrow metaphases, Clin Cancer Res 9 (2003), 1489-1496.
16. B.P. Patel, U.M. Rawal, R.M. Rawal, S.N. Shukla and P.S. Patel, Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer, Am J Clin Oncol 31 (2008), 454-459.
17. E.M. Sturgis, A review of social and behavioral efforts at oral cancer prevention in India, Head & Neck 26 (2004), 937-944.
18. S. Kawanishi and S. Oikawa, Mechanism of telomere shortening by oxidative stress, Ann N Y Acad Sci 1019 (2004), 278-284.
19. R. Kumaraguruparan, R. Subapriya, P. Viswanathan and S. Nagini, Tissue lipid peroxidation and antioxidant status in patients with adenocarcinoma of the breast, Clin Chin Acta 325 (2002), 165-170.
20. M. Muller, Cellular senescence: Molecular mechanisms, invivo significance, and redox considerations, Antioxid Redox Signal, 11 (2009), 59-98.
21. R.M. Rawal, D.D. Patel, B.P. Patel, M.M. Patel, M.K. Wadhwa, P.S. Patel and J.M. Bhatavdekar, Assessment of glutathione-S-transferase and glutathione reductase in patients with squamous-cell carcinoma of buccal mucosa, Int J Cancer 83 (1999), 727-731.
22. A.T.Naveen, C. Adithan, N. Padmaja, C.H. Shashindran, B.K. Abraham, K. Satyanarayanamoorthy, P. Anitha, N. Gerard and R. Krishnamoorthy, Glutathione S-transferase M1 and T1 null genotype distribution in South Indians, Eur J Clin Pharmacol 60 (2004), 403-406.
23. T.T. Sreelekha, K. Ramadas, M. Pandey, G. Thomas, K.R. Nalinakumari and M.R. Pillai, Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer, Oral Oncol 37 (2001), 593-598.
24. D. Anantharaman, P.M. Chaubal, S. Kannan, R.A. Bhisey and M.B. Mahimkar, Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: Tobacco exposure as a risk modulator, Carcinogenesis 28 (2007), 1455-1462.
25. M. Singh, P.P. Shah, A.P. Singh, M. Ruwali, N. Mathur, M.C. Pant and D. Parmar, Association of genetic polymorphisms in glutathione S-transferases and susceptibility to head and neck cancer, Mutat Res 638 (2008), 184-194.
26. M.M. Patel, D.D. Patel, L.J. Parekh, G.N. Raval, R.M. Rawal, J.M. Bhatavdekar and P.S. Patel, Evaluation of telomerase activation in head and neck cancer, Oral Oncol 35 (1999), 510-515.
27. A.K. Meeker, J.L. Hicks, A. Christine, I. Donahue, E.A. Montgomery, W.H.Westra, T.H. Chan, B.M. Ronnett and A.M. De Marzo, Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis, Clin Cancer Res 10 (2004), 3317-3326.
28. R.N. Sainger, S.D. Telang, S.N. Shukla and P.S. Patel, Clinical significance of telomere length and associated proteins in oral cancer, Biomarker Insights 2 (2007), 12-22.
29. M.M. Patel, L.J. Parekh, F.P. Jha, R.N. Sainger, J.B. Patel, D.D. Patel, P.M. Shah and P.S. Patel, Clinical usefulness of telomerase activation and telomere length in head & neck cancer, Head & Neck 24 (2002), 1060-1067.
30. R. Rosenberg, R. Gertler, D. Stricker, S. Lassmann, M.Werner, H. Nekarda and J.R. Siewert, Telomere length and hTERT expression in patients with colorectal carcinoma, Recent Results Cancer Res 162 (2003), 177-181.
31. T. Minamino, S.A. Mitsialis and S. Kourembanas, Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation, Mol Cell Biol 21 (2001), 3336-3342.
32. T. von Zglinicki, Oxidative stress shortens telomeres, Trends Biochem Sci, 27 (2002), 339-344.
33. D.Y. Liu, Z.H. Peng, G.Q. Qiu and C.Z. Zhou, Expression of telomerase activity and oxidative stress in human hepatocellular carcinoma with cirrhosis, World J Gastroenterol 9 (2003), 1859-1862.
34. V. Serra, T. von Zglinicki, M. Lorenz and G.J. Saretzki, Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening, Biol Chem 278 (2003), 6824-6830.