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Volumn 86, Issue 3, 2009, Pages 545-548

The antihypoxia-adenosinergic pathogenesis as a result of collateral damage by overactive immune cells

Author keywords

Adenosine receptors; Caffeine; HIF 1 ; Hypoxia; Inflammation; Oxygen; T cells

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 70149095024     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0908577     Document Type: Short Survey
Times cited : (12)

References (43)
  • 1
    • 34548227265 scopus 로고    scopus 로고
    • Targeting immunosupportive cancer therapies: Accentuate the positive, eliminate the negative
    • Peggs, K. S., Segal, N. H., Allison, J. P. (2007) Targeting immunosupportive cancer therapies: accentuate the positive, eliminate the negative. Cancer Cell 12, 192-199.
    • (2007) Cancer Cell , vol.12 , pp. 192-199
    • Peggs, K.S.1    Segal, N.H.2    Allison, J.P.3
  • 2
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • DOI 10.1038/414916a
    • Ohta, A., Sitkovsky, M. (2001) Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414, 916-920. (Pubitemid 34024743)
    • (2001) Nature , vol.414 , Issue.6866 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 4
    • 19544391973 scopus 로고    scopus 로고
    • The "danger" sensors that STOP the immune response: The A2 adenosine receptors?
    • Sitkovsky, M. V., Ohta, A. (2005) The "danger" sensors that STOP the immune response: the A2 adenosine receptors? Trends Immunol. 26, 299-304.
    • (2005) Trends Immunol. , vol.26 , pp. 299-304
    • Sitkovsky, M.V.1    Ohta, A.2
  • 5
    • 25444454359 scopus 로고    scopus 로고
    • Regulation of immune cells by local-tissue oxygen tension: HIF1α and adenosine receptors
    • DOI 10.1038/nri1685, PII NRI1685
    • Sitkovsky, M., Lukashev, D. (2005) Regulation of immune cells by local-tissue oxygen tension: HIF1α and adenosine receptors. Nat. Rev. Immunol. 5, 712-721. (Pubitemid 43086172)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.9 , pp. 712-721
    • Sitkovsky, M.1    Lukashev, D.2
  • 6
    • 0035966119 scopus 로고    scopus 로고
    • Differential Regulation of Two Alternatively Spliced Isoforms of Hypoxia-inducible Factor-1α in Activated T Lymphocytes
    • DOI 10.1074/jbc.M104782200
    • Lukashev, D., Caldwell, C., Ohta, A., Chen, P., Sitkovsky, M. (2001) Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 α in activated T lymphocytes. J. Biol. Chem. 276, 48754-48763. (Pubitemid 37370572)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.52 , pp. 48754-48763
    • Lukashev, D.1    Caldwell, C.2    Ohta, A.3    Chen, P.4    Sitkovsky, M.5
  • 10
    • 0030803163 scopus 로고    scopus 로고
    • Memory of extracellular adenosine A(2a) purinergic receptor-mediated signaling in murine T cells
    • DOI 10.1074/jbc.272.41.25881
    • Koshiba, M., Kojima, H., Huang, S., Apasov, S., Sitkovsky, M. V. (1997) Memory of extracellular adenosine/A2a purinergic receptor-mediated signaling in murine T cells. J. Biol. Chem. 272, 25881-25889. (Pubitemid 27438913)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.41 , pp. 25881-25889
    • Koshiba, M.1    Kojima, H.2    Huang, S.3    Apasov, S.4    Sitkovsky, M.V.5
  • 11
    • 0030878807 scopus 로고    scopus 로고
    • Role of A2a adenosine receptor-mediated signaling in inhibition of T cell activation and expansion
    • Huang, S., Koshiba, M., Apasov, S., Sitkovsky, M. (1997) Role of A2a adenosine receptor-mediated signaling in inhibition of T cell activation and expansion. Blood 90, 1600-1610.
    • (1997) Blood , vol.90 , pp. 1600-1610
    • Huang, S.1    Koshiba, M.2    Apasov, S.3    Sitkovsky, M.4
  • 12
    • 0032190614 scopus 로고    scopus 로고
    • 2 homeostasis
    • DOI 10.1016/S0959-437X(98)80016-6
    • Semenza, G. L. (1998) Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr. Opin. Genet. Dev. 8, 588-594. (Pubitemid 28477364)
    • (1998) Current Opinion in Genetics and Development , vol.8 , Issue.5 , pp. 588-594
    • Semenza, G.L.1
  • 13
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • DOI 10.1146/annurev.cellbio.15.1.551
    • Semenza, G. L. (1999) Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15, 551-578. (Pubitemid 32250386)
    • (1999) Annual Review of Cell and Developmental Biology , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 16
    • 0030747295 scopus 로고    scopus 로고
    • Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release
    • Decking, U. K., Schlieper, G., Kroll, K., Schrader, J. (1997) Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release. Circ. Res. 81, 154-164. (Pubitemid 27342482)
    • (1997) Circulation Research , vol.81 , Issue.2 , pp. 154-164
    • Decking, U.K.M.1    Schlieper, G.2    Kroll, K.3    Schrader, J.4
  • 17
    • 47049088629 scopus 로고    scopus 로고
    • HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
    • Morote-Garcia, J. C., Rosenberger, P., Kuhlicke, J., Eltzschig, H. K. (2008) HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak. Blood 111, 5571-5580.
    • (2008) Blood , vol.111 , pp. 5571-5580
    • Morote-Garcia, J.C.1    Rosenberger, P.2    Kuhlicke, J.3    Eltzschig, H.K.4
  • 18
    • 61849148133 scopus 로고    scopus 로고
    • Damage control by hypoxia-inhibited AK
    • Sitkovsky, M. V. (2008) Damage control by hypoxia-inhibited AK. Blood 111, 5424-5425.
    • (2008) Blood , vol.111 , pp. 5424-5425
    • Sitkovsky, M.V.1
  • 19
    • 33750929739 scopus 로고    scopus 로고
    • ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function
    • DOI 10.1161/01.RES.0000250174.31269.70, PII 0000301220061110000012
    • Eltzschig, H. K., Eckle, T., Mager, A., Kuper, N., Karcher, C., Weissmuller, T., Boengler, K., Schulz, R., Robson, S. C., Colgan, S. P. (2006) ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ. Res. 99, 1100-1108. (Pubitemid 44729934)
    • (2006) Circulation Research , vol.99 , Issue.10 , pp. 1100-1108
    • Eltzschig, H.K.1    Eckle, T.2    Mager, A.3    Kuper, N.4    Karcher, C.5    Weissmuller, T.6    Boengler, K.7    Schulz, R.8    Robson, S.C.9    Colgan, S.P.10
  • 20
    • 18044366362 scopus 로고    scopus 로고
    • Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation
    • DOI 10.1055/s-2005-869527
    • Robson, S. C., Wu, Y., Sun, X., Knosalla, C., Dwyer, K., Enjyoji, K. (2005) Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation. Semin. Thromb. Hemost. 31, 217-233. (Pubitemid 40605196)
    • (2005) Seminars in Thrombosis and Hemostasis , vol.31 , Issue.2 , pp. 217-233
    • Robson, S.C.1    Wu, Y.2    Sun, X.3    Knosalla, C.4    Dwyer, K.5    Enjyoji, K.6
  • 22
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
    • Fredholm, B. B., Ijzerman, A. P., Jacobson, K. A., Klotz, K-N., Linden, J. (2001) International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors. Pharmacol. Rev. 53, 527-552.
    • (2001) Pharmacol. Rev. , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.-N.4    Linden, J.5
  • 23
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • Fredholm, B. B., Battig, K., Holmen, J., Nehlig, A., Zvartau, E. E. (1999) Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol. Rev. 51, 83-133. (Pubitemid 29113867)
    • (1999) Pharmacological Reviews , vol.51 , Issue.1 , pp. 83-133
    • Fredholm, B.B.1    Battig, K.2    Holmen, J.3    Nehlig, A.4    Zvartau, E.E.5
  • 24
    • 0035040532 scopus 로고    scopus 로고
    • Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection
    • DOI 10.1146/annurev.pharmtox.41.1.775
    • Linden, J. (2001) Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection. Annu. Rev. Pharmacol. Toxicol. 41, 775-787. (Pubitemid 32385906)
    • (2001) Annual Review of Pharmacology and Toxicology , vol.41 , pp. 775-787
    • Linden, J.1
  • 25
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • Jacobson, K. A., Gao, Z. G. (2006) Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5, 247-264.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 27
    • 0037441343 scopus 로고    scopus 로고
    • 2A adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo
    • DOI 10.1016/S0006-2952(02)01548-4, PII S0006295202015484
    • Sitkovsky, M. V. (2003) Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo. Biochem. Pharmacol. 65, 493-501. (Pubitemid 36144234)
    • (2003) Biochemical Pharmacology , vol.65 , Issue.4 , pp. 493-501
    • Sitkovsky, M.V.1
  • 28
    • 0032586888 scopus 로고    scopus 로고
    • Patterns of A(2A) extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A(2A) receptor monoclonal antibodies
    • Koshiba, M., Rosin, D. L., Hayashi, N., Linden, J., Sitkovsky, M. V. (1999) Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies. Mol. Pharmacol. 55, 614-624. (Pubitemid 29128120)
    • (1999) Molecular Pharmacology , vol.55 , Issue.3 , pp. 614-624
    • Koshiba, M.1    Rosin, D.L.2    Hayashi, N.3    Linden, J.4    Sitkovsky, M.V.5
  • 29
    • 0024539189 scopus 로고
    • Potential use of an antagonist of cAMP-dependent protein kinase to block inhibition and modulate T-cell receptor-triggered activation of cytotoxic T-lymphocytes
    • DOI 10.1002/jps.2600780104
    • Takayama, H., Sitkovsky, M. V. (1989) Potential use of antagonists of cAMP-dependent protein kinase to block inhibition and modulate T-cell receptor-triggered activation of cytotoxic T-lymphocytes. J. Pharm. Sci. 78, 8-10. (Pubitemid 19079802)
    • (1989) Journal of Pharmaceutical Sciences , vol.78 , Issue.1 , pp. 8-10
    • Takayama, H.1    Sitkovsky, M.V.2
  • 30
    • 0026483939 scopus 로고
    • The dual role of the cAMP-dependent protein kinase C α subunit in T-cell receptor-triggered T-lymphocytes effector functions
    • Sugiyama, H., Chen, P., Hunter, M., Taffs, R., Sitkovsky, M. (1992) The dual role of the cAMP-dependent protein kinase C α subunit in T-cell receptor-triggered T-lymphocytes effector functions. J. Biol. Chem. 267, 25256-25263.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25256-25263
    • Sugiyama, H.1    Chen, P.2    Hunter, M.3    Taffs, R.4    Sitkovsky, M.5
  • 31
    • 0036136463 scopus 로고    scopus 로고
    • Molecular mechanisms for protein kinase A-mediated modulation of immune function
    • DOI 10.1016/S0898-6568(01)00214-5, PII S0898656801002145
    • Torgersen, K. M., Vang, T., Abrahamsen, H., Yaqub, S., Tasken, K. (2002) Molecular mechanisms for protein kinase A-mediated modulation of immune function. Cell. Signal. 14, 1-9. (Pubitemid 34020823)
    • (2002) Cellular Signalling , vol.14 , Issue.1 , pp. 1-9
    • Torgersen, K.M.1    Vang, T.2    Abrahamsen, H.3    Yaqub, S.4    Tasken, K.5
  • 32
    • 0034019537 scopus 로고    scopus 로고
    • Essential role of nitric oxide and interferon-γ for tumor immunotherapy with interleukin-10
    • DOI 10.1097/00002371-200003000-00005
    • Sun, H., Gutierrez, P., Jackson, M. J., Kundu, N., Fulton, A. M. (2000) Essential role of nitric oxide and interferon-γ for tumor immunotherapy with interleukin-10. J. Immunother. 23, 208-214. (Pubitemid 30165170)
    • (2000) Journal of Immunotherapy , vol.23 , Issue.2 , pp. 208-214
    • Sun, H.1    Gutierrez, P.2    Jackson, M.J.3    Kundu, N.4    Fulton, A.M.5
  • 33
    • 0037442129 scopus 로고    scopus 로고
    • TNF plays an essential role in tumor regression after adoptive transfer of perforin/IFN-γ double knockout effector T cells
    • Poehlein, C. H., Hu, H. M., Yamada, J., Assmann, I., Alvord, W. G., Urba, W. J., Fox, B. A. (2003) TNF plays an essential role in tumor regression after adoptive transfer of perforin/IFN-γ double knockout effector T cells. J. Immunol. 170, 2004-2013. (Pubitemid 36197421)
    • (2003) Journal of Immunology , vol.170 , Issue.4 , pp. 2004-2013
    • Poehlein, C.H.1    Hu, H.-M.2    Yamada, J.3    Assmann, I.4    Gregory Alvord, W.5    Urba, W.J.6    Fox, B.A.7
  • 34
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. (2003) Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 36
    • 0035575975 scopus 로고    scopus 로고
    • Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
    • Caldwell, C. C., Kojima, H., Lukashev, D., Armstrong, J., Farber, M., Apasov, S. G., Sitkovsky, M. V. (2001) Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions. J. Immunol. 167, 6140-6149. (Pubitemid 33081540)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6140-6149
    • Caldwell, C.C.1    Kojima, H.2    Lukashev, D.3    Armstrong, J.4    Farber, M.5    Apasov, S.G.6    Sitkovsky, M.V.7
  • 37
    • 22744450934 scopus 로고    scopus 로고
    • Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
    • DOI 10.1371/journal.pbio.0030174, e174
    • Thiel, M., Chouker, A., Ohta, A., Jackson, E., Caldwell, C., Smith, P., Lukashev, D., Bittmann, I., Sitkovsky, M. V. (2005) Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury. PLoS Biol. 3, e174. (Pubitemid 41032218)
    • (2005) PLoS Biology , vol.3 , Issue.6 , pp. 1088-1100
    • Thiel, M.1    Chouker, A.2    Ohta, A.3    Jackson, E.4    Caldwell, C.5    Smith, P.6    Lukashev, D.7    Bittmann, I.8    Sitkovsky, M.V.9
  • 38
    • 0028859662 scopus 로고
    • Adenosine, adenosine receptors and the actions of caffeine
    • Fredholm, B. B. (1995) Adenosine, adenosine receptors and the actions of caffeine. Pharmacol. Toxicol. 76, 93-101.
    • (1995) Pharmacol. Toxicol. , vol.76 , pp. 93-101
    • Fredholm, B.B.1
  • 39
    • 34250703015 scopus 로고    scopus 로고
    • 2A signaling
    • DOI 10.1016/j.pneurobio.2007.07.005, PII S0301008207001311, Targeting Adenosine A2A Receptors in Parkinson's Disease and other CNS Disorders
    • Fredholm, B. B., Chern, Y., Franco, R., Sitkovsky, M. (2007) Aspects of the general biology of adenosine A2A signaling. Prog. Neurobiol. 83, 263-276. (Pubitemid 350102746)
    • (2007) Progress in Neurobiology , vol.83 , Issue.5 , pp. 263-276
    • Fredholm, B.B.1    Chern, Y.2    Franco, R.3    Sitkovsky, M.4
  • 40
    • 38849133578 scopus 로고    scopus 로고
    • 1,3,7-Trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism
    • Ohta, A., Lukashev, D., Jackson, E. K., Fredholm, B. B., Sitkovsky, M. (2007) 1,3,7-Trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism. J. Immunol. 179, 7431-7438.
    • (2007) J. Immunol. , vol.179 , pp. 7431-7438
    • Ohta, A.1    Lukashev, D.2    Jackson, E.K.3    Fredholm, B.B.4    Sitkovsky, M.5


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