Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs

Molecular Medicine

Volumn 15, Issue 9-10, 2009, Pages 297-306

  Dapas, Barbara ^a   Farra, Rossella ^a   Grassi, Mario ^b   Giansante, Carlo ^a   Fiotti, Nicola ^a   Uxa, Laura ^a   Rainaldi, Giuseppe ^c   Mercatanti, Alberto ^c   Colombatti, Alfonso ^d   Spessotto, Paola ^d   Lacovich, Valentina ^a   Guarnieri, Gianfranco ^a   Grassi, Gabriele ^a,b  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c CNR   (Italy)

^d CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A2; CYCLIN E; CYCLIN E1; CYCLIN E2; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL CYCLE; CELL DEATH; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY VASCULAR SMOOTH MUSCLE CELL; DIABETES MELLITUS; DOWN REGULATION; ENZYME INHIBITION; FEMALE; HUMAN; HYPERGLYCEMIA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA SYNTHESIS; SMOOTH MUSCLE FIBER;

ADULT; ANALYSIS OF VARIANCE; CELL DEATH; CELL GROWTH PROCESSES; CELL MOVEMENT; CELLS, CULTURED; CORONARY VESSELS; CYCLIN E; CYCLINS; DOWN-REGULATION; E2F1 TRANSCRIPTION FACTOR; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; ONCOGENE PROTEINS; RNA, SMALL INTERFERING;

EID: 70149095010     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2009.00030     Document Type: Article

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