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Volumn 106, Issue 34, 2009, Pages 14490-14495

Uncoupling CD21 and CD19 of the B-cell coreceptor

Author keywords

B cell memory; Complement receptors; Germinal centers; Humoral immunity

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD19 ANTIGEN; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; COMPLEMENT RECEPTOR;

EID: 70149092551     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903477106     Document Type: Article
Times cited : (33)

References (57)
  • 1
    • 0030593030 scopus 로고    scopus 로고
    • C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    • Dempsey P, Allison M, Akkaraju S, Goodnow C, Fearon D (1996) C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity. Science 271:348-350. (Pubitemid 3021509)
    • (1996) Science , vol.271 , Issue.5247 , pp. 348-350
    • Dempsey, P.W.1    Allison, M.E.2    Akkaraju, S.3    Goodnow, C.C.4    Fearon, D.T.5
  • 2
    • 0024955886 scopus 로고
    • Approaching the asymptote: Evolution and revolution in immunology
    • Janeway CA (1989) Approaching the asymptote: Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 54:1-13.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 3
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P (1994) Tolerance, danger, and the extended family. Annu Rev Immunol 12:991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 4
    • 43949157081 scopus 로고
    • The CD19/CD21 signal transduction complex of B lymphocytes
    • Tedder TF, Zhou LJ, Engel P (1994) The CD19/CD21 signal transduction complex of B lymphocytes. Immunol Today 15:437-441.
    • (1994) Immunol Today , vol.15 , pp. 437-441
    • Tedder, T.F.1    Zhou, L.J.2    Engel, P.3
  • 6
    • 0025255536 scopus 로고
    • The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1
    • Kurtz CB, O'Toole E, Christensen SM,Weis JH (1990) The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1. J Immunol 144:3581-3591. (Pubitemid 20146398)
    • (1990) Journal of Immunology , vol.144 , Issue.9 , pp. 3581-3591
    • Kurtz, C.B.1    O'Toole, E.2    Christensen, S.M.3    Weis, J.H.4
  • 7
    • 0028181481 scopus 로고
    • Binding of C3b and C4b by the CR1-like site in murine CR1
    • Kalli KR, Fearon DT (1994) Binding of C3b and C4b by the CR1-like site in murine CR1. J Immunol 152:2899-2903. (Pubitemid 24097987)
    • (1994) Journal of Immunology , vol.152 , Issue.6 , pp. 2899-2903
    • Kalli, K.R.1    Fearon, D.T.2
  • 8
    • 0025127325 scopus 로고
    • In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody
    • DOI 10.1084/jem.172.2.665
    • Heyman B, Wiersma EJ, Kinoshita T (1990) In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody. J Exp Med 172:665-668. (Pubitemid 20248411)
    • (1990) Journal of Experimental Medicine , vol.172 , Issue.2 , pp. 665-668
    • Heyman, B.1    Wiersma, E.J.2    Kinoshita, T.3
  • 9
    • 0026014521 scopus 로고
    • Inhibition of immunological memory and T-independent humoral responses by monoclonal antibodies specific for murine complement receptors
    • Wiersma EJ, Kinoshita T, Heyman B (1991) Inhibition of immunological memory and T-independent humoral responses by monoclonal antibodies specific for murine complement receptors. Eur J Immunol 21:2501-2506.
    • (1991) Eur J Immunol , vol.21 , pp. 2501-2506
    • Wiersma, E.J.1    Kinoshita, T.2    Heyman, B.3
  • 10
    • 0025936951 scopus 로고
    • Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo
    • Typhronitis G, et al. (1991) Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo. J Immunol 147:224-230.
    • (1991) J Immunol , vol.147 , pp. 224-230
    • Typhronitis, G.1
  • 11
    • 0025991505 scopus 로고
    • Suppression of the immune response by a soluble complement receptor of B lymphocytes
    • Hebell T, Ahearn JM, Fearon DT (1991) Supression of the immune response by a soluble complement receptor of B lymphocytes. Science 254:102-105. (Pubitemid 21917326)
    • (1991) Science , vol.254 , Issue.5028 , pp. 102-105
    • Hebell, T.1    Ahearn, J.M.2    Fearon, D.T.3
  • 12
    • 0034232062 scopus 로고    scopus 로고
    • Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
    • Guinamard R, Okigaki M, Schlessinger J, Ravetch JV (2000) Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat Immunol 1:31-36.
    • (2000) Nat Immunol , vol.1 , pp. 31-36
    • Guinamard, R.1    Okigaki, M.2    Schlessinger, J.3    Ravetch, J.V.4
  • 13
    • 1242341404 scopus 로고    scopus 로고
    • Approaching the speed limit for Greek Key beta-barrel formation: Transition-state movement tunes folding rate of zinc-substituted azurin
    • DOI 10.1016/S1570-9639(03)00240-1
    • Pozdnyakova I, Wittung-Stafshede P (2003) Approaching the speed limit for Greek Key beta-barrel formation: Transition-state movement tunes folding rate of zinc-substituted azurin. Biochim Biophys Acta 1651:1-4. (Pubitemid 38234547)
    • (2003) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1651 , Issue.1-2 , pp. 1-4
    • Pozdnyakova, I.1    Wittung-Stafshede, P.2
  • 14
    • 0032753625 scopus 로고    scopus 로고
    • Protective T cell-independent antiviral antibody responses are dependent on complement
    • Ochsenbien A, et al. (1999) Protective T cell-independent antiviral antibody responses are dependent on complement. J Exp Med 190:1165-1174.
    • (1999) J Exp Med , vol.190 , pp. 1165-1174
    • Ochsenbien, A.1
  • 15
    • 0032562609 scopus 로고    scopus 로고
    • Dependence of germinal center B cells on expression of CD21/CD35 for survival
    • Fischer MB, et al. (1998) Dependence of germinal center B cells on expression of CD21/CD35 for survival. Science 280:582-585.
    • (1998) Science , vol.280 , pp. 582-585
    • Fischer, M.B.1
  • 18
    • 18744396051 scopus 로고    scopus 로고
    • Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses
    • Haas KM, et al. (2002) Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. Immunity 17:713-723.
    • (2002) Immunity , vol.17 , pp. 713-723
    • Haas, K.M.1
  • 19
    • 0033607253 scopus 로고    scopus 로고
    • Humoral response to herpes simplex virus is complement dependent
    • DaCosta X, et al. (1999) Humoral response to herpes simplex virus is complement dependent. Proc Natl Acad Sci USA 96:12708-12712.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12708-12712
    • DaCosta, X.1
  • 20
    • 57649146305 scopus 로고    scopus 로고
    • Complement and natural antibody are required in the long term memory response to influenza virus
    • Gonzalez SF, Jayasekera JP, Carroll MC (2008) Complement and natural antibody are required in the long term memory response to influenza virus. Vaccine 26S:186-193.
    • (2008) Vaccine , vol.26 S , pp. 186-193
    • Gonzalez, S.F.1    Jayasekera, J.P.2    Carroll, M.C.3
  • 21
    • 0032104018 scopus 로고    scopus 로고
    • Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response
    • Fang Y, Xu C, Fu Y, Holers VM,Molina H (1998) Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response. J Immunol 160:5273-5279. (Pubitemid 28267813)
    • (1998) Journal of Immunology , vol.160 , Issue.11 , pp. 5273-5279
    • Fang, Y.1    Xu, C.2    Fu, Y.-X.3    Holers, V.M.4    Molina, H.5
  • 23
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • DOI 10.1038/ni1542, PII NI1542
    • Cinamon G, Zachariah MA, Lam OM, Foss FW, Jr, Cyster JG (2008) Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol 9:54-62. (Pubitemid 350286204)
    • (2008) Nature Immunology , vol.9 , Issue.1 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3    Foss Jr., F.W.4    Cyster, J.G.5
  • 24
    • 5044252309 scopus 로고    scopus 로고
    • Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells
    • Ferguson AR, Youd ME, Corley RB (2004) Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int Immunol 16:1411-1422.
    • (2004) Int Immunol , vol.16 , pp. 1411-1422
    • Ferguson, A.R.1    Youd, M.E.2    Corley, R.B.3
  • 25
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • DOI 10.1038/ni1494, PII NI1494
    • Phan TG, Grigorova I, Okada T, Cyster JG (2007) Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol 8:992-1000. (Pubitemid 47300014)
    • (2007) Nature Immunology , vol.8 , Issue.9 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 26
    • 60149086845 scopus 로고    scopus 로고
    • Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
    • Roozendaal R, et al. (2009) Conduits mediate transport of low-molecular-weight antigen to lymph node follicles. Immunity 30:264-276.
    • (2009) Immunity , vol.30 , pp. 264-276
    • Roozendaal, R.1
  • 29
    • 34247842905 scopus 로고    scopus 로고
    • Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/Ipr mice via both complement-dependent and -independent mechanisms
    • DOI 10.2353/ajpath.2007.060601
    • Miwa T, et al. (2007) Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms. Am J Pathol 170:1258-1266. (Pubitemid 47339333)
    • (2007) American Journal of Pathology , vol.170 , Issue.4 , pp. 1258-1266
    • Miwa, T.1    Maldonado, M.A.2    Zhou, L.3    Yamada, K.4    Gilkeson, G.S.5    Eisenberg, R.A.6    Song, W.-C.7
  • 30
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for murine complement regulator Crry in fetomaternal tolerance
    • DOI 10.1126/science.287.5452.498
    • Xu C, et al. (2000) A critical role for murine complement regulator crry in fetomaternal tolerance. Science 287:498-501. (Pubitemid 33595260)
    • (2000) Science , vol.287 , Issue.5452 , pp. 498-501
    • Xu, C.1    Mao, D.2    Holers, V.M.3    Palanca, B.4    Cheng, A.M.5    Molina, H.6
  • 31
    • 51549119790 scopus 로고    scopus 로고
    • Comparative functional evolution of human and mouse CR1 and CR2
    • Jacobson AC, Weis JH (2008) Comparative functional evolution of human and mouse CR1 and CR2. J Immunol 181:2953-2959.
    • (2008) J Immunol , vol.181 , pp. 2953-2959
    • Jacobson, A.C.1    Weis, J.H.2
  • 32
    • 0027218596 scopus 로고
    • Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes
    • Matsumoto AK, et al. (1993) Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes. J Exp Med 178:1407-1417.
    • (1993) J Exp Med , vol.178 , pp. 1407-1417
    • Matsumoto, A.K.1
  • 33
    • 0035884992 scopus 로고    scopus 로고
    • CD19 can regulate B lymphocyte signal transduction independent of complement activation
    • Hasegawa M, Fujimoto M, Poe JC, Steeber DA, Tedder TF (2001) CD19 can regulate B lymphocyte signal transduction independent of complement activation. J Immunol 167:3190-3200. (Pubitemid 32852558)
    • (2001) Journal of Immunology , vol.167 , Issue.6 , pp. 3190-3200
    • Hasegawa, M.1    Fujimoto, M.2    Poe, J.C.3    Steeber, D.A.4    Tedder, T.F.5
  • 34
    • 23844503253 scopus 로고    scopus 로고
    • CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses
    • Barrington RA, et al. (2005) CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses. J Immunol 175:2859-2867.
    • (2005) J Immunol , vol.175 , pp. 2859-2867
    • Barrington, R.A.1
  • 36
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow CC, et al. (1988) Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334:676-682.
    • (1988) Nature , vol.334 , pp. 676-682
    • Goodnow, C.C.1
  • 37
    • 14844351587 scopus 로고    scopus 로고
    • Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway
    • Lyubchenko T, dal Porto J, Cambier JC, Holers VM (2005) Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway. J Immunol 174:3264-3272.
    • (2005) J Immunol , vol.174 , pp. 3264-3272
    • Lyubchenko, T.1    Dal Porto, J.2    Cambier, J.C.3    Holers, V.M.4
  • 38
    • 0035399831 scopus 로고    scopus 로고
    • The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens
    • Cherukuri A, Cheng PC, Pierce SK (2001) The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens. J Immunol167:163-172. (Pubitemid 32567774)
    • (2001) Journal of Immunology , vol.167 , Issue.1 , pp. 163-172
    • Cherukuri, A.1    Cheng, P.C.2    Pierce, S.K.3
  • 40
    • 0034614896 scopus 로고    scopus 로고
    • Bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells
    • Smith KG, et al. (2000) bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells. J Exp Med 191:475-484.
    • (2000) J Exp Med , vol.191 , pp. 475-484
    • Smith, K.G.1
  • 42
    • 0028324816 scopus 로고
    • Germinal centers
    • MacLennan I (1994) Germinal centers. Ann Rev Immunol 12:117-139.
    • (1994) Ann Rev Immunol , vol.12 , pp. 117-139
    • MacLennan, I.1
  • 43
    • 0037350859 scopus 로고    scopus 로고
    • Helper T-cell-regulated B-cell immunity
    • McHeyzer-Williams M, et al. (2003) Helper T-cell-regulated B-cell immunity. Microbes Infect 5:205-212.
    • (2003) Microbes Infect , vol.5 , pp. 205-212
    • McHeyzer-Williams, M.1
  • 45
    • 20444501371 scopus 로고    scopus 로고
    • CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers
    • DOI 10.1016/j.immuni.2005.04.012, PII S1074761305001445
    • Wang Y, Carter RH (2005) CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers. Immunity 22:749-761. (Pubitemid 40814505)
    • (2005) Immunity , vol.22 , Issue.6 , pp. 749-761
    • Wang, Y.1    Carter, R.H.2
  • 46
    • 0035099092 scopus 로고    scopus 로고
    • The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts
    • Cherukuri A, Cheng PC, Sohn HW, Pierce SK (2001) The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts. Immunity 14:169-179. (Pubitemid 32206519)
    • (2001) Immunity , vol.14 , Issue.2 , pp. 169-179
    • Cherukuri, A.1    Cheng, P.C.2    Sohn, H.W.3    Pierce, S.K.4
  • 47
    • 0347994950 scopus 로고    scopus 로고
    • The Tetraspanin CD81 Is Necessary for Partitioning of Coligated CD19/ CD21-B Cell Antigen Receptor Complexes into Signaling-Active Lipid Rafts
    • Cherukuri A, et al. (2004) The tetraspanin CD81 is necessary for partitioning of coligated CD19/CD21-B cell antigen receptor complexes into signaling-active lipid rafts. J Immunol 172:370-380. (Pubitemid 38020491)
    • (2004) Journal of Immunology , vol.172 , Issue.1 , pp. 370-380
    • Cherukuri, A.1    Shoham, T.2    Sohn, H.W.3    Levy, S.4    Brooks, S.5    Carter, R.6    Pierce, S.K.7
  • 48
    • 0030948267 scopus 로고    scopus 로고
    • Normal lymphocyte development but delayed humoral immune response in CD81-null mice
    • Maecker HT, Levy S (1997) Normal lymphocyte development but delayed humoral immune response in CD81-null mice. J Exp Med 185:1505-1510.
    • (1997) J Exp Med , vol.185 , pp. 1505-1510
    • Maecker, H.T.1    Levy, S.2
  • 49
    • 0030886882 scopus 로고    scopus 로고
    • Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice
    • Tsitsikov EN, Gutierrez-Ramos JC, Geha RS (1997) Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice. Proc Natl Acad Sci USA 94:10844-10849.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10844-10849
    • Tsitsikov, E.N.1    Gutierrez-Ramos, J.C.2    Geha, R.S.3
  • 50
    • 0029064680 scopus 로고
    • Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
    • Rickert RC, Rajewsky K, Roes J (1995) Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature 376:352-355.
    • (1995) Nature , vol.376 , pp. 352-355
    • Rickert, R.C.1    Rajewsky, K.2    Roes, J.3
  • 51
    • 0033561682 scopus 로고    scopus 로고
    • Cutting edge: Recruitment of the CD19/CD21 coreceptor to B cell antigen receptor is required for antigen-mediated expression of Bcl-2 by resting and cycling hen egg lysozyme transgenic B cells
    • Roberts T, Snow EC (1999) Recruitment of the CD19/CD21 Coreceptor to B cell antigen receptor is required for antigen-mediated expression of B cl-2 by resting and cycling hen egg lysozyme transgenic B cells. J Immunol 162:4377-4380. (Pubitemid 29314831)
    • (1999) Journal of Immunology , vol.162 , Issue.8 , pp. 4377-4380
    • Roberts, T.1    Snow, E.C.2
  • 52
  • 53
    • 17144418984 scopus 로고    scopus 로고
    • Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1
    • DOI 10.1084/jem.20042239
    • Gatto D, et al. (2005) Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1. J Exp Med 201:993-1005. (Pubitemid 40524468)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.6 , pp. 993-1005
    • Gatto, D.1    Pfister, T.2    Jegerlehner, A.3    Martin, S.W.4    Kopf, M.5    Bachmann, M.F.6
  • 54
    • 0042422053 scopus 로고    scopus 로고
    • The B cell receptor itself can activate complement to provide the complement receptor 1/2 ligand required to enhance B cell immune responses in vivo
    • DOI 10.1084/jem.20022042
    • Rossbacher J, Shlomchik MJ (2003) The B cell receptor itself can activate complement to provide the complement receptor 1/2 ligand required to enhance B cell immune responses in vivo. J Exp Med 198:591-602. (Pubitemid 37040393)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.4 , pp. 591-602
    • Rossbacher, J.1    Shlomchik, M.J.2
  • 56
    • 0032525007 scopus 로고    scopus 로고
    • Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM
    • Boes M, et al. (1998) Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM. J Immunol 160:4776-4787. (Pubitemid 28215311)
    • (1998) Journal of Immunology , vol.160 , Issue.10 , pp. 4776-4787
    • Boes, M.1    Esau, C.2    Fischer, M.B.3    Schmidt, T.4    Carroll, M.5    Chen, J.6
  • 57
    • 0035545679 scopus 로고    scopus 로고
    • Generation of recombinant human C3dg tetramers for the analysis of CD21 binding and function
    • DOI 10.1016/S0022-1759(01)00471-9, PII S0022175901004719
    • Henson SE, Smith D, Boackle SA, Holers VM, Karp DR (2001) Generation of recombinant human C3dg tetramers for the analysis of CD21 binding and function. J Immunol Methods 258:97-109. (Pubitemid 33016530)
    • (2001) Journal of Immunological Methods , vol.258 , Issue.1-2 , pp. 97-109
    • Henson, S.E.1    Smith, D.2    Boackle, S.A.3    Holers, V.M.4    Karp, D.R.5


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